Transdermal versus oral estrogen: clinical outcomes in patients undergoing frozen-thawed single blastocyst transfer cycles without GnRHa suppression, a prospective randomized clinical trial

Journal of Assisted Reproduction and Genetics

Volumn 36, Issue 3, 2019, Pages 453-459

  Kahraman, Semra ^a   Çetinkaya, Caroline Pirkevi ^a   Sahin, Yucel ^a   Oner, Gokalp ^a  

^a MEMORIAL HOSPITAL   (Turkey)

Author keywords

Cycle outcomes; Endometrial thickness; Oral estrogen; Transdermal estrogen

Indexed keywords

ESTRADIOL; ESTRADIOL VALERATE; PROGESTERONE; ESTROGEN; GONADORELIN;

ADULT; ANOVULATION; ARTICLE; BLASTOCYST; CLINICAL OUTCOME; COMPARATIVE STUDY; CONTROLLED STUDY; ECHOGRAPHY; EMBRYO TRANSFER; ENDOMETRIAL THICKNESS; ESTROGEN THERAPY; FEMALE; FREEZE THAWING; FROZEN THAWED EMBRYO TRANSFER; HUMAN; INFERTILITY THERAPY; MAJOR CLINICAL STUDY; MENSTRUATION; PREGNANCY RATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TRANSVAGINAL ECHOGRAPHY; VITRIFICATION; CRYOPRESERVATION; CUTANEOUS DRUG ADMINISTRATION; ENDOMETRIUM; METABOLISM; NIDATION; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PREGNANCY; PROCEDURES;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ADULT; CRYOPRESERVATION; EMBRYO IMPLANTATION; EMBRYO TRANSFER; ENDOMETRIUM; ESTRADIOL; ESTROGENS; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; PREGNANCY; PREGNANCY RATE; PROGESTERONE;

EID: 85058056558     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-018-1380-5     Document Type: Article

References (18)

1. Wong KM, Mastenbroek S, Repping S. Cryopreservation of human embryos and its contribution to in vitro fertilization success rates. Fertil Steril. 2014;102(1):19–26.
2. Roque M, Lattes K, Serra S, Solà I, Geber S, Carreras R, et al. Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles: a systematic review and meta-analysis. Fertil Steril. 2013;99(1):156–62.
3. Roque M, Valle M, Guimarães F, Sampaio M, Geber S. Freeze-all policy: fresh vs. frozen-thawed embryo transfer. Fertil Steril. 2015;103(5):1190–3.
4. Zhu Q, Chen Q, Wang L, Lu X, Lyu Q, Wang Y, et al. Live birth rates in the first complete IVF cycle among 20 687 women using a freeze-all strategy. Hum Reprod. 2018;33(5):924–9.
5. Madero S, Rodriguez A, Vassena R, Vernaeve V. Endometrial preparation: effect of estrogen dose and administration route on reproductive outcomes in oocyte donation cycles with fresh embryo transfer. Hum Reprod. 2016;31(8):1755–64.
6. Glujovsky D, Pesce R, Fiszbajn G, Sueldo C, Hart RJ, Ciapponi A. Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes. Cochrane Database Syst Rev. 2010;(1):CD006359.
7. Ebner T, Vanderzwalmen P, Shebl O, Urdl W, Moser M, Zech NH, et al. Morphology of vitrified/warmed day-5 embryos predicts rates of implantation, pregnancy and live birth. Reprod BioMed Online. 2009;19(1):72–8.
8. Shahrokh Tehraninejad E, Kabodmehri R, Hosein Rashidi B, Jafarabadi M, Keikha F, Masomi M, et al. Transdermal estrogen (oestrogel) for endometrial preparation in freeze embryo transfer cycle: An RCT. Int J Reprod Biomed (Yazd). 2018;16(1):51–6.
9. Patel SS, Carr BR. Oocyte quality in adult polycystic ovary syndrome. Semin Reprod Med. 2008;26(2):196–203.
10. Dumesic DA, Padmanabhan V, Abbott DH. Polycystic ovary syndrome and oocyte developmental competence. Obstet Gynecol Surv. 2008;63(1):39–48.
11. Qiao J, Feng HL. Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence. Hum Reprod Update. 2011;17(1):17–33.
12. Davar R, Janati S, Mohseni F, Khabazkhoob M, Asgari SA. Comparison of the effects of transdermal estradiol and estradiol valerate on endometrial receptivity in frozen-thawed embryo transfer cycles: a randomized clinical trial. J Reprod Infertil. 2016;17(2):97–103.
13. Ghobara T, Gelbaya TA, Ayeleke RO. Cycle regimens for frozen-thawed embryo transfer. Cochrane Database Syst Rev. 2017;7:CD003414.
14. Powers MS, Schenkel L, Darley PE, Good WR, Balestra JC, Place VA. Pharmacokinetics and pharmacodynamics of transdermal dosage forms of 17β-estradiol: comparison with conventional oral estrogens used for hormone replacement. Am J Obstet Gynecol. 1985;152:1099–106.
15. Burks H, Paulson R. Cryopreserved embryo transfer: endometrial preparation and timing. Semin Reprod Med. 2015;33(2):145–52.
16. Krasnow JS, Lessey BA, Naus G, Hall LL, Guzick DS, Berga SL. Comparison of transdermal versus oral estradiol on endometrial receptivity. Fertil Steril. 1996;65(2):332–6.
17. Mackens S, Santos-Ribeiro S, van de Vijver A, Racca A, Van Landuyt L, Tournaye H, et al. Frozen embryo transfer: a review on the optimal endometrial preparation and timing. Hum Reprod. 2017;32(11):2234–42.
18. Wilcox AJ, Baird DD, Weinberg CR. Time of implantation of the conceptus and loss of pregnancy. N Engl J Med. 1999;340:1796–9.