Murine models of Pneumocystis infection recapitulate human primary immune disorders

JCI insight

Volumn 3, Issue 12, 2018, Pages

  Elsegeiny, Waleed ^a,b,c   Zheng, Mingquan ^a,b   Eddens, Taylor ^a,b,c   Gallo, Richard L ^d   Dai, Guixiang ^e   Trevejo Nunez, Giraldina ^a,b   Castillo, Patricia ^a,b,c   Kracinovsky, Kara ^a,b   Cleveland, Hillary ^a,b   Horne, William ^a   Franks, Jonathan ^f   Pociask, Derek ^e   Pilarski, Mark ^a   Alcorn, John F ^b   Chen, Kong ^a,b   Kolls, Jay K ^a,b,e  

^a Richard King Mellon Foundation Institute for Pediatric Research and

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Cytokines; Fungal infections; Immunology; Infectious disease; T cells

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CSF2 PROTEIN, HUMAN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IL21R PROTEIN, HUMAN; INTERLEUKIN 21 RECEPTOR ALPHA; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE;

ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CD4+ T LYMPHOCYTE; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOPATHOLOGY; KNOCKOUT MOUSE; METABOLISM; MOUSE; PATHOLOGY; PNEUMOCYSTIS; PNEUMOCYSTOSIS; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNE SYSTEM DISEASES; INTERLEUKIN-21 RECEPTOR ALPHA SUBUNIT; INTERLEUKINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PNEUMOCYSTIS; PNEUMOCYSTIS INFECTIONS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 85057912311     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.91894     Document Type: Article

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