Soy saponin

Soy in Health and Disease Prevention

Volumn , Issue , 2005, Pages 155-172

  Tsukamoto, Chigen ^a   Yoshiki, Yumiko ^b  

^a IWATE UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85057680549     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (50)

1. Fenwick, G.R., Price, K.R., Tsukamoto, C., and Okubo, K., Saponins, in Toxic Substances in Crop Plants, D’Mollo, J.P.F., Duffus, C.M., and Duffus, J.H., Eds., Royal Society of Chemistry, Cambridge, UK, 1991, pp. 285-327, 1991.
2. Tsukamoto, C., Kikuchi, A., Harada, K., Kitamura, K., and Okubo, K., Genetic and chemical polymorphisms of saponins in soybean seed, Phytochemistry, 34, 1351-1356, 1993.
3. Kudou, S., Tonomura, M., Tsukamoto, C., Uchida, T., Sakabe, T., Tamura, N., and Okubo, K., Isolation and structural elucidation of DDMP-conjugated soyasaponins as genuine saponins from soybean seeds, Biosci. Biotechnol. Biochem., 57, 546-550, 1993.
4. Shimoyamada, M., Kudo, S., Okubo, K., Yamauchi, F., and Harada, K., Distribution of saponins constituents in some varieties of soybean plant, Agric. Biol. Chem., 54, 77-81, 1990.
5. Tsukamoto, C., Kikuchi, A., Kudou, S., Harada, K., Kitamura, K., and Okubo, K., Group A acetyl saponin-deficient mutant from the wild soybean, Phytochemistry, 31, 4139-4142, 1992.
6. Tsukamoto, C., Kikuchi, A., Takada, Y., Kono, Y., Harada, K., Kitamura, K., and Okubo, K., Genetic improvement of soybean saponins, in Proceedings of IV International Soybean Processing and Utilization Conference, PR, Brazil, 822-829, 2004.
7. Shiraiwa, M., Yamauchi, F., Harada, K., and Okubo, K., Inheritance of “Group A saponin” in soybean seed, Agric. Biol. Chem., 54, 1347-1352, 1990.
8. Kikuchi, A., Tsukamoto, C., Tabuchi, K., Adachi, T., and Okubo, K., Inheritance and characterization of a null allele for Group A acetyl saponins found in a mutant soybean (Glycine max (L.) Merrill), Breed. Sci., 49, 167-171, 1999.
9. Shiraiwa, M., Kudo, S., Shimoyamada, M., Harada, K., and Okubo, K., Composition and structure of “Group A saponin” in soybean seed, Agric. Biol. Chem., 55, 315-322, 1991.
10. Tsukamoto, C., Kikuchi, A., Kudou, S., Harada, K., Iwasaki T., and Okubo, K., Genetic improvement of saponin components in soybean, in ACS Symposium Series 546, Food Phytochemicals for Cancer Prevention I, Huang, M.T., Osawa, T., Ho, C.T., and Rosen, R.T., Eds., American Chemical Society, Washington, DC, 1994, pp. 372-379.
11. Gestetner, B., Birk, Y., and Tencer, Y., Soybean saponins: fate of ingested soybean saponins and the physiological aspect of their hemolytic activity, J. Agric. Food Chem., 16, 1031-1035, 1968.
12. Yoshikoshi, M., Kahara, T., Yoshiki, Y., Ito, M., Furukawa, Y., Okubo, K., and Amarowicz, R., Metabolism and nonabsorption of soybean hypocotyls saponins in the rat model, Acta Aliment., 24, 355-364, 1995.
13. Ono, R. and Yamaguchi, M., Anabolic effect of soybean saponin on bone components in the femoral tissues of rats, J. Health Sci., 45, 251-255, 1999.
14. Oakenfull, D.G. and Topping, L.D., Saponins and plasma cholesterol, Atherosclerosis, 48, 301-303, 1983.
15. Pathirana, C., Gibney, M.J., and Taylar, T.G., The effect of dietary protein source and saponins on serum lipids and the excretion of bile acids and neutral sterols in rabbits, Br. J. Nutr., 46, 421-430, 1981.
16. Ueda, H. and Matsumoto, A., Effects of soybean saponin and soybean protein on serum cholesterol concentration in cholesterol-fed chicks, Anim. Sci. Technol. Jpn., 67, 415-422, 1996.
17. Oakenfull, D.G. and Fenwick, D.E., Adsorption of bile salts from aqueous solution by plant fibre and cholestyramine, Br. J. Nutr., 10, 299-309, 1978.
18. Oakenfull, D.G., Fenwick, D.E., Hood, R.L., Topping, D.L., Illman, R.L., and Storer, G.B., Effects of saponins on bile acids and plasma lipids in the rat, Br. J. Nutr., 42, 209-216, 1979.
19. Topping, D.L., Storer, G.B., Calvert, G.D., Illman, R.J., Oakenfull, D.G., and Weller, R.A., Effects of dietary saponins on fecal bile acids and neutral sterols, plasma lipids, and lipoprotein turnover in the pig, Am. J. Clin. Nutr., 33, 783-786, 1980.
20. Messina, M.J., Persky, V., Setchell, K.D.R., and Barnes, S., Soy intake and cancer risk: a review of the in vitro and in vivo data, Nutr. Cancer, 21, 113-131, 1994.
21. Koshimizu, K., Ohigashi, H., Tokuda, H., Kondo, A., and Yamaguchi, K., Screening of edible plants against possible anti-tumor promoting activity, Cancer Lett., 39, 247-257, 1988.
22. Maeda, H., Katsuki, T., Akaike, T., and Yasutake, R., High correlation between lipid peroxide radical and tumor-promoter effect: suppression of tumor promotion in the Epstein-Barr virus/B-lymphocyte system and scavenging of alkyl peroxide radicals by various vegetable extracts, Jpn. J. Cancer Res., 83, 923-928, 1992.
23. Konoshima, T., Kozuka, M., Haruna, M., and Ito, K., Constituents of leguminous plants. XIII. New triterpenoid saponins from Wistaria brachybotry, J. Nat. Prod., 54, 830-836, 1991.
24. Konoshima, T., Antitumor-promoting activities of triterpenoid glycosides: cancer chemoprevention by saponins, in Saponins Used in Traditional and Modern Medicine: Advances in Experimental Medicine and Biology, Waller, G.R. and Yamasaki, K., Eds., Plenum Press, New York, 1996, pp. 87-100.
25. Sung, M., Kendall, C.W.C., Koo, M.M., and Rao, A.V., Effect of soybean saponins and gypsophilla saponin on growth and viability of colon carcinoma cells in culture, Nutr. Cancer, 23, 259-270, 1995.
26. Oh, Y. and Sung, M., Soybean saponins inhibit cell proliferation by suppressing PKC activation and induce differentiation of HT-29 human colon adenocarcinoma cells, Nutr. Cancer, 39, 132-138, 2001.
27. Shiraiwa, M., Harada, K., and Okubo, K., Composition and content of saponins in soybean seed according to variety, cultivation year and maturity, Agric. Biol. Chem., 55, 323-331, 1991.
28. Hausen, H., Viruses in human cancers, Science, 254, 1167-1173, 1991.
29. Varmus, H., Retroviruses, Science, 240, 1427-1435, 1988.
30. Nakashima, K., Okubo, K., Honda, Y., Tamura, T., Matsuda, S., and Yamamoto, N., Inhibitory effect of glycosides like saponin from soybean on the infectivity of HIV in vitro, AIDS, 3, 655-658, 1989.
31. Hayashi, K., Hayashi, H., Hiraoka, N., and Ikeshiro, Y., Inhibitory activity of soyasaponin II on virus replication in vitro, Planta Med., 63, 102-105, 1997.
32. Namba, T., Yoshizaki, M., Tomimori, T., Kobashi, K., Mitsui, K., and Hase, J., Hemolytic and its protective activity of ginseng saponins, Chem. Pharm. Bull., 21, 459-461, 1973.
33. Hilf, R., Goldenberg, H., Michel, I., Orlando, R.A., and Archer, F.L., Enzymes, nucleic acids, and lipids in human breast cancer and normal breast tissue, Cancer Res., 30, 1874-1882, 1970.
34. Birk, Y., Bondi, A., Gestetner, B., and Ishaaya, I., A thermostable maemolytic factor in soybeans, Nature, 197, 1089-1090, 1963.
35. Massiot, G., Dijoux, M., and Lavaud, C., Saponins and artifacts, in Saponins Used in Food and Agriculture: Advances in Experimental Medicine and Biolgy, Waller, G.R. and Yamasaki, K., Eds., Plenum Press, New York, 1996, pp. 183-192.
36. Ohminami, H., Kimura, Y., Okuda, H., Arichi, S., Yoshikawa, M., and Kitagawa, I., Effects of soyasaponins on liver injury induced by highly peroxidized fat in rats, Planta Med., 50, 440-441, 1984.
37. Miyao, H., Arao, T., Udayama, M., Kinjo, J., and Nohara, T., Kaikasaponin III and soyasaponin I, major triterpene saponins of Abrus cantoniensis, act on GOT and GPT: influence on transaminase elevation of rat liver cells concomitantly exposed to CCl4 for one hour, Planta Med., 64, 5-7, 1998.
38. Kinjo, J., Udayama, M., Hatakeyama, M., Ikeda, T., Sohno, Y., Yoshiki, Y., Okubo, K., and Nohara, T., Hepatoprotective effects of oleanene glucuronides in several edible beans, Nat. Med., 53, 141-144, 1999.
39. Kinjo, J., Imagire, M., Udayama, M., Arao, T., and Nohara, T., Structurehepatoprotective relationships study of soyasaponins I-IV having soyasapogenol B as aglycone, Planta Med., 64, 233-236, 1998.
40. Yoshikoshi, M., Yoshiki, Y., Okubo, K., Seto, J., and Sasaki, Y., Prevention hydrogen peroxide damage by soybean saponins to mouse fibroblasts, Planta Med., 62, 252-255, 1996.
41. Halliwell, B. and Gutteridge, J.M.C., The antioxidants of human extracellular fluids, Arch. Biochem. Biophys., 280, 1-8, 1990.
42. Tsujino, Y., Tsurumi, S., Yoshida, Y., and Niki, E., Antioxidative effects of dihydro-γ-pyronyl-triterpenoid saponin (chromosaponin I), Biosci. Biotechnol. Biochem., 58, 1731-1732, 1994.
43. Nishida, K., Ohta, Y., Araki, Y., Ito, M., Nagamura, Y., and Ishiguro, I., Inhibitory effects of “group A saponin” and “group B saponin” fractions from soybean seed hypocotyls on radical-initiated lipid peroxidation in mouse liver microsomes, J. Clin. Biochem. Nutr., 15, 175-184, 1993.
44. Kudou, S., Tonomura, M., Tsukamoto, C., Shimoyamada, M., and Okubo, K., Isolation and structural elucidation of the major genuine soybean saponin, Biosci. Biotechnol. Biochem., 56, 142-143, 1992.
45. Massiot, J., Lavaud, C., Venkhaled, M., and LeMen-Olivier, L., Saponin VI, a new maltol conjugate from alfalfa and soybean, J. Nat. Prod., 55, 1339-1342, 1992.
46. Tsurumi, S., Takagi, T., and Hashimoto, T., A γ-pyronyl-triterpennoid saponin from Pisum sativum, Phytochemistry, 31, 2435-2438, 1992.
47. Yoshiki, Y. and Okubo, K., Active oxygen scavenging activity of DDMP (2,3- dihydro-2,5-dihydroxy-6-methyl-4H-pyran-4-one) saponin in soybean seed, Biosci. Biotechnol. Biochem., 59, 1556-1557, 1995.
48. Yoshiki, Y., Kahara, T., Okubo, K., Sakabe, T., and Yamasaki, T., Superoxide- and 1,1-diphenyl-2-picrylhydrazyl radical-scavenging activities of soyasaponin βg related to gallic acid. Biosci. Biotechnol. Biochem., 65, 2162-2165, 2001.
49. Yoshiki, Y., Kudou, S., and Okubo, K., Relationship between chemical structures and biological activities of triterpenoid saponins from soybean, Biosci. Biotechnol. Biochem., 62, 2291-2299, 1998.
50. Kitagawa, I., Saito, M., Taniyama, T., and Yoshikawa, M., Saponin and sapogenol. XXXVIII. Structure of soyasaponin A2, a bisdesmoside of soysapogenol A, from soybean, the seeds of Glycine max MERRILL, Chem. Pharm. Bull., 33, 598-608, 1985.