Long-term outcomes following first short-term clinically important deterioration in COPD

Respiratory Research

Volumn 19, Issue 1, 2018, Pages

  Naya, Ian P ^a   Tombs, Lee ^a   Muellerova, Hana ^a   Compton, Christopher ^a   Jones, Paul W ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Clinically important deterioration; Composite measures; COPD; Mortality

Indexed keywords

CORTICOSTEROID; FLUTICASONE PROPIONATE; FLUTICASONE PROPIONATE PLUS SALMETEROL; PLACEBO; SALMETEROL; BRONCHODILATING AGENT;

ADULT; AGED; ALL CAUSE MORTALITY; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DETERIORATION; DISEASE EXACERBATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HAZARD RATIO; HEALTH STATUS; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREDICTION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK ASSESSMENT; ST. GEORGE RESPIRATORY QUESTIONNAIRE; SURVIVOR; VERY ELDERLY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; TIME FACTOR; TREATMENT OUTCOME;

AGED; BRONCHODILATOR AGENTS; CLINICAL DETERIORATION; DISEASE PROGRESSION; DOUBLE-BLIND METHOD; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RETROSPECTIVE STUDIES; SURVEYS AND QUESTIONNAIRES; TIME FACTORS; TREATMENT OUTCOME;

EID: 85056727798     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-018-0928-3     Document Type: Article

References (38)

1. Casanova C, Aguirre-Jaime A, de Torres JP, Pinto-Plata V, Baz R, Marin JM, et al. Longitudinal assessment in COPD patients: multidimensional variability and outcomes. Eur Respir J. 2014;43:745-53.
2. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med. 2004;350:1005-12.
3. GOLD. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Updated 2018. http://goldcopd.org. Accessed 21 May 2018.
4. Jones PW, Donohue JF, Nedelman J, Pascoe S, Pinault G, Lassen C. Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis. Respir Res. 2011;12:161.
5. Westwood M, Bourbeau J, Jones PW, Cerulli A, Capkun-Niggli G, Worthy G. Relationship between FEV1 change and patient-reported outcomes in randomised trials of inhaled bronchodilators for stable COPD: a systematic review. Respir Res. 2011;12:40.
6. Calverley PM, Postma DS, Anzueto AR, Make BJ, Eriksson G, Peterson S, et al. Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations. Int J Chron Obstruct Pulmon Dis. 2016;11:381-90.
7. Martin AL, Marvel J, Fahrbach K, Cadarette SM, Wilcox TK, Donohue JF. The association of lung function and St. George's respiratory questionnaire with exacerbations in COPD: a systematic literature review and regression analysis. Respir Res. 2016;17:40.
8. Agusti A, Calverley PM, Celli B, Coxson HO, Edwards LD, Lomas DA, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res. 2010;11:122.
9. Oga T, Tsukino M, Hajiro T, Ikeda A, Koyama H, Mishima M, et al. Multidimensional analyses of long-term clinical courses of asthma and chronic obstructive pulmonary disease. Allergol Int. 2010;59:257-65.
10. Singh D, Maleki-Yazdi MR, Tombs L, Iqbal A, Fahy WA, Naya I. Prevention of clinically important deteriorations in COPD with umeclidinium/vilanterol. Int J Chron Obstruct Pulmon Dis. 2016;11:1413-24.
11. Donohue JF. Minimal clinically important differences in COPD lung function. COPD. 2005;2:111-24.
12. Jones PW. St. George's respiratory questionnaire: MCID. COPD. 2005;2:75-9.
13. Anzueto AR, Kostikas K, Mezzi K, Shen S, Larbig M, Patalano F, et al. Indacaterol/glycopyrronium versus salmeterol/fluticasone in the prevention of clinically important deterioration in COPD: results from the FLAME study. Respir Res. 2018;19:121.
14. Anzueto AR, Vogelmeier CF, Kostikas K, Mezzi K, Fucile S, Bader G, et al. The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD. Int J Chron Obstruct Pulmon Dis. 2017;12:1325-37.
15. Buhl R, McGarvey L, Korn S, Ferguson GT, Gronke L, Hallmann C, et al. Benefits of tiotropium + olodaterol over tiotropium at delaying clinically significant events in patients with COPD classified as GOLD B. Am J Respir Crit Care Med. 2016;193:A6779.
16. Maleki-Yazdi MR, Singh D, Anzueto A, Tombs L, Fahy WA, Naya I. Assessing short-term deterioration in maintenance-naive patients with COPD receiving umeclidinium/vilanterol and tiotropium: a pooled analysis of three randomized trials. Adv Ther. 2016;33(12):2188-99.
17. Naya I, Compton C, Ismaila A, Birk R, Brealey N, Tabberer M, et al. Preventing clinically important deterioration with single-inhaler triple therapy in COPD. ERJ Open Res. 2018; In press.
18. Naya I, Tombs L, Lipson D, Compton C. Preventing clinically important deterioration of COPD with addition of umeclidinium to inhaled corticosteroid/long-acting β2-agonist therapy:an integrated post hoc analysis. Adv Ther. 2018; In press.
19. Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med. 2007;356:775-89.
20. Vestbo J, Anderson W, Coxson HO, Crim C, Dawber F, Edwards L, et al. Evaluation of COPD longitudinally to identify predictive surrogate end-points (ECLIPSE). Eur Respir J. 2008;31:869-73.
21. Vestbo J. The TORCH (towards a revolution in COPD health) survival study protocol. Eur Respir J. 2004;24:206-10.
22. Spencer S, Calverley PM, Sherwood Burge P, Jones PW, Disease ISGISiOL. Health status deterioration in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001;163:122-8.
23. Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M. Exercise capacity deterioration in patients with COPD: longitudinal evaluation over 5 years. Chest. 2005;128:62-9.
24. Waschki B, Kirsten AM, Holz O, Mueller KC, Schaper M, Sack AL, et al. Disease progression and changes in physical activity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015;192:295-306.
25. Nagai K, Makita H, Suzuki M, Shimizu K, Konno S, Ito YM, et al. Differential changes in quality of life components over 5 years in chronic obstructive pulmonary disease patients. Int J Chron Obstruct Pulmon Dis. 2015;10:745-57.
26. Celli BR, Thomas NE, Anderson JA, Ferguson GT, Jenkins CR, Jones PW, et al. Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study. Am J Respir Crit Care Med. 2008;178:332-8.
27. Han MK, Halpin DMG, Martinez FJ, Miravitlles M, Singh D, de la Hoz A, et al. A composite endpoint of clinically important deterioration in chronic obstructive pulmonary disease and its association with increased mortality: a post hoc analysis of the UPLIFT study. Am J Respir Crit Care Med. 2018;197:A4245.
28. Naya I, Driessen MT, Paly V, Gunsoy N, Risebrough N, Briggs A, et al. Long-term consequences of clinically important deterioration in patients with chronic obstructive pulmonary disease treated with twice-daily inhaled corticosteroid/long-acting β2-agonist therapy: results from the TORCH study. Am J Respir Crit Care Med. 2018;197:A3042.
29. Wilke S, Jones PW, Mullerova H, Vestbo J, Tal-Singer R, Franssen FM, et al. One-year change in health status and subsequent outcomes in COPD. Thorax. 2015;70:420-5.
30. Naya I, Tombs L, Jones P. Short-term clinically important deterioration predicts long-term clinical outcome in COPD patients: a post-hoc analysis of the TORCH trial. Thorax. 2015;70:A34-5.
31. Naya I, Tombs L, Jones P. Combination therapy with inhaled salmeterol plus fluticasone propionate is more effective than salmeterol alone in reducing the risk of clinically important deterioration in COPD: a post-hoc analysis of the TORCH trial. Thorax. 2015;70:A136-A37.
32. Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N. Development and first validation of the COPD assessment test. Eur Respir J. 2009;34:648-54.
33. Kon SS, Canavan JL, Jones SE, Nolan CM, Clark AL, Dickson MJ, et al. Minimum clinically important difference for the COPD assessment test: a prospective analysis. Lancet Respir Med. 2014;2:195-203.
34. Lipson DA, Barnacle H, Birk R, Brealey N, Locantore N, Lomas DA, et al. FULFIL trial: once-daily triple therapy for patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2017;196:438-46.
35. Lipson DA, Barnhart F, Brealey N, Brooks J, Criner GJ, Day NC, et al. Once-daily single-inhaler triple versus dual therapy in patients with COPD. N Engl J Med. 2018;378:1671-80.
36. Rabe KF, Halpin D, Martinez F, Singh D, Han MK, Zehendner CM, et al. Relative timing of clinically important deterioration and related long-term outcomes in copd: a post hoc analysis of the uplift study. Pneumologie. 2018;72:86-7.
37. Naya I, Tombs L, Mullerova H, Compton C, Jones P. Long-term outcome following first clinically important deterioration in COPD. Eur Respir J. 2016;48:PA304.
38. Vestbo J, Anderson JA, Calverley PM, Celli B, Ferguson GT, Jenkins C, et al. Bias due to withdrawal in long-term randomised trials in COPD: evidence from the TORCH study. Clin Respir J. 2011;5:44-9.