Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides

Nucleic acids research

Volumn 46, Issue 7, 2018, Pages 3579-3594

  Wang, Shiyu ^a   Allen, Nickolas ^a   Vickers, Timothy A ^a   Revenko, Alexey S ^a   Sun, Hong ^a   Liang, Xue Hai ^a   Crooke, Stanley T ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MEMBRANE PROTEIN; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; PROTEIN BINDING;

CELL MEMBRANE; CHEMISTRY; ENDOCYTOSIS; ENDOSOME; GENETIC TRANSFECTION; GENETICS; HELA CELL LINE; HUMAN; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CELL MEMBRANE; ENDOCYTOSIS; ENDOSOMES; EPIDERMAL GROWTH FACTOR; ERBB RECEPTORS; HELA CELLS; HUMANS; MEMBRANE PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 85055401883     PISSN: None     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gky145     Document Type: Article

References (0)