Probiotic Bacillus enhance the intestinal epithelial cell barrier and immune function of piglets

Beneficial Microbes

Volumn 9, Issue 5, 2018, Pages 743-754

  Du, W ^a   Xu, H ^a   Mei, X ^a   Cao, X ^a   Gong, L ^a   Wu, Y ^a   Li, Y ^a   Yu, D ^a   Liu, S ^b   Wang, Y ^a   Li, W ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b National Animal Husbandry Service   (China)

Author keywords

Bacillus amyloliquefaciens SC06; Gut immunity; Intestinal barrier; Tight junction; TLRs

Indexed keywords

ALPHA INTERFERON; BINDING PROTEIN; CHLORTETRACYCLINE; CLAUDIN 3; CLAUDIN 4; DEFENSIN; DEFENSIN 1; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MUCIN 1; MYELOID DIFFERENTIATION FACTOR 88; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN CONTAINING PROTEIN 1; PROBIOTIC AGENT; TIGHT JUNCTION PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VILLIN; CYTOKINE;

ANIMAL CELL; ARTICLE; BACILLUS AMYLOLIQUEFACIENS; BACTERIUM ISOLATION; CELL COUNT; CELL STRUCTURE; CONTROLLED STUDY; CRYPT CELL; CYTOKINE RELEASE; DOWN REGULATION; GENE EXPRESSION; GOBLET CELL; IMMUNE SYSTEM; INTESTINAL EPITHELIAL CELL BARRIER; INTESTINE VILLUS; NONHUMAN; PERMEABILITY BARRIER; PIGLET; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; DRUG EFFECT; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; MALE; MICROBIOLOGY; PHYSIOLOGY; PIG; PRECLINICAL STUDY;

ANIMALS; BACILLUS AMYLOLIQUEFACIENS; CLAUDIN-3; CLAUDIN-4; CYTOKINES; DEFENSINS; DRUG EVALUATION, PRECLINICAL; EPITHELIAL CELLS; INTESTINAL MUCOSA; MALE; PROBIOTICS; SWINE;

EID: 85054530544     PISSN: 18762883     EISSN: 18762891     Source Type: Journal    
DOI: 10.3920/BM2017.0142     Document Type: Article

References (40)

1. Adrew, S., Mark, H. and Yoichi, C., 2007. The effects of acute psychological stress on circulating inflammatory factors in humans: A review and meta-Analysis. Brain, Behavior, and Immunity 21: 901-912.
2. Bodera, P. and Chcialowski, A., 2009. Immunomodulatory effect of probiotic bacteria. Recent Patents on Inflammation and Allergy Drug Discovery 3: 58-64.
3. Borg, B.S., Libal, G.M. and Wahlstrom, R.C., 1987. Tryptophan and threonine requirements of young pigs and their effects on serum calcium, phosphorus and zinc concentrations. Journal of Animal Science 64: 1070-1078.
4. Bowie, A.G. and Haga, I.R., 2005. The role of Toll-like receptors in the host response to viruses. Molecular Immunology 42: 859-867.
5. Buzza, M.S., Johnson, T.A., Conway, G.D., Martin, E.W., Mukhopadhyay, S., Shea-Donohue, T. and Antalis, T.M., 2017. Inflammatory cytokines down-regulate the barrier protective prostasin-matriptase proteolytic cascade early in experimental colitis. Journal of Biological Chemistry 292: 10801-10812.
6. Castillo, N.A., Perdigón, G. and de Moreno de Leblanc, A., 2011. Oral administration of a probiotic Lactobacillus modulates cytokine production and TLR expression improving the immune response against Salmonella enterica serovar Typhimurium infection in mice. BMC Microbiology 11: 177-188.
7. Chen, Z., Xie, J., Hu, M.Y., Tang, J., Shao, Z.F. and Li, M.H., 2015. Protective effects of γ-Aminobutyric acid (GABA) on the small intestinal mucosa in heat-stressed Wenchang chicken. Journal of Animal and Plant Sciences 25: 78-87.
8. Chu, G.M., Jung, C.K., Kim, H.Y., Ha, J.H., Kim, J.H., Jung, M.S., Lee, S.J., Song, Y., Ibrahim, R.I.H., Cho, J.H., Lee, S.S. and Song, Y.M., 2013. Effects of bamboo charcoal and bamboo vinegar as antibiotic alternatives on growth performance, immune responses and fecal microflora population in fattening pigs. Animal Science Journal 84: 113-120.
9. Collado, M.C., Grzekowiak, U. and Salminen, S., 2007. Probiotic strains and their combination inhibit in vitro adhesion of pathogens to pig intestinal mucosa. Current Microbiology 55: 260.
10. Dai, C., Zhao, D.H. and Jiang, M., 2012. VSL# 3 probiotics regulate the intestinal epithelial barrier in vivo and in vitro via the p38 and ERK signaling pathways. International Journal of Molecular Medicine 29: 202-208.
11. De LeBlanc, A.M. and LeBlanc, J.G., 2014. Effect of probiotic administration on the intestinal microbiota, current knowledge and potential applications. World Journal of Gastroenterology 20: 16518.
12. Fasano, A., 2011. Zonulin and its regulation of intestinal barrier function: The biological door to inflammation, autoimmunity, and cancer. Physiological Reviews 91: 151-175.
13. Ghadimi, D., Vrese, M., Heller, K.J. and Schrezenmeir, J., 2010. Effect of natural commensal-origin DNA on Toll-like receptor 9 (TLR9) signaling cascade, chemokine IL-8 expression, and barrier integritiy of polarized intestinal epithelial cells. Inflammatory Bowel Diseases 16: 410-427.
14. Han, X., Fink, M.P. and Delude, R.L., 2003. Proinflammatory cytokines cause NO-dependent and-independent changes in expression and localization of tight junction proteins in intestinal epithelial cells. Shock 19: 229-237.
15. Harata, G., He, F. and Kawase, M., 2009. Differentiated implication of Lactobacillus GG and L. gasseri TMC0356 to immune responses of murine Peyer's patch. Microbiology and Immunology 53: 475-480.
16. He, Y., Franchi, L. and Núñez, G., 2012. TLR agonists stimulate Nlrp3- dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo. Journal of Immunology 190: 334-339.
17. Hemaiswarya, S., Raja, R., Ravikumar, R. and Carvalho, I.S., 2013. Mechanism of action of probiotics. Brazilian Archives of Biology and Technology 56: 113-119.
18. Jiang, Y., Lü, X., Man, C., Han, L., Shan, Y., Qu, X., Liu, Y., Yang, S., Xue, Y. and Zhang, Y., 2012. Lactobacillus acidophilus induces cytokine and chemokine production via NF-κB and p38 mitogen-Activated protein kinase signaling pathways in intestinal epithelial cells. Clinical and Vaccine Immunology 19: 603-608.
19. Johnson-Henry, K.C., Donato, K.A., Shen-Tu, G., Gordanpour, M. and Sherman, P.M., 2008. Lactobacillus rhamnosus strain GG prevents enterohemorrhagic Escherichia coli O157: H7-induced changes in epithelial barrier function. Infection and Immunity 76: 1340-1348.
20. Kang, Y.J., Seit-Nebi, A., Davis, R.J. and Han, J., 2006. Multiple activation mechanisms of p38alpha mitogen-Activated protein kinase. Journal of Biological Chemistry 281: 26225-26234.
21. Liu, F.N., Li, G.H., Wen, K., Bui, T. and Cao, Y.M., 2010. Porcine small intestinal epithelial cell line (IPEC-J2) of rotavirus infection as a new model for the study of innate immune responses to rotaviruses and probiotics. Viral Immunology 23: 135-149.
22. Liu, Z., Shen, T., Zhang, P., Ma, Y. and Qin, H., 2011. Lactobacillus plantarum surface layer adhesive protein protects intestinal epithelial cells against tight junction injury induced by enteropathogenic Escherichia coli. Molecular Biology Reports 38: 3471-3480.
23. Mennigen, R., Nolte, K. and Rijcken, E., 2009. Probiotic mixture VSL# 3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis. American Journal of Physiology - Gastrointestinal and Liver Physiology 296: G1140-G1149.
24. Moeser, A.J., Ryan, K.A., Nighot, P.K. and Blikslager, A.T., 2007. Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs. American Journal of Physiology - Gastrointestinal and Liver Physiology 293: G413-G421.
25. Mohamadzadeh, M. and Klaenhammer, T.R., 2008. Specific Lactobacillus species differentially activate Toll-like receptors and downstream signals in dendritic cells. Expert Review Vaccines 7: 1155-1164.
26. Moorthy, G., Murali, M.R. and Devaraj, S.N., 2009. Lactobacilli facilitate maintenance of intestinal membrane integrity during Shigella dysenteriae 1 infection in rats. Nutrition 25: 350-358.
27. National Research Council (NRC), 1998. Nutrient requirements of swine. National Academies Press, Washington, DC, USA.
28. Nissen, L., Chingwaru, W., Sgorbati, B., Biavati, B. and Cencic, A., 2009. Gut health promoting activity of new putative probiotic/protective Lactobacillus spp. strains: A functional study in the small intestinal cell model. International Journal of Food Microbiology 135: 288-294.
29. Oelschlaeger, T.A., 2010. Mechanisms of probiotic actions -A review. International Journal of Medical Microbiology 300: 57-62.
30. Pagnini, C., Saeed, R., Bamias, G., Arseneau, K.O., Pizarro, T.T. and Cominelli, F., 2010. Probiotics promote gut health through stimulation of epithelial innate immunity. Proceedings of the National Academy of Sciences of the USA 107: 454-459.
31. Rahn, E., Thier, K., Petermann, P., Rübsam, M., Staeheli, P., Iden, S., Niessen, C.M. and Knebel-Mörsdorf, D., 2017. Epithelial barriers in murine skin during herpes simplex virus 1 infection: The role of tight junction formation. Journal of Investigative Dermatology 137: 884-893.
32. Robinson, K., Deng, Z., Hou, Y. and Zhang, G., 2015. Regulation of the intestinal barrier function by host defense peptides. Frontiers in Veterinary Science 2: 57.
33. Suzuki, T., 2013. Regulation of intestinal epithelial permeability by tight junctions. Cellular and Molecular Life Sciences 70: 631-659.
34. Tsukita, S., Furuse, M. and Itoh, M., 2001. Multifunctional strands in tight junctions. Nature Reviews Molecular Cell Biology 2: 285-293.
35. Wang, Y., Wu, Y., Wang, B., Cao, X., Fu, A., Li, Y. and Li, W., 2017. Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets. AMB Express 7: 52.
36. West, N.P., Pyne, D.B., Peake, J.M. and Cripps, A.W., 2009. Probiotics, immunity and exercise: A review. Exercise Immunology Review 15: 107-126.
37. Wu, Y., Wang, Y., Zou, H., Wang, B., Sun, Q., Fu, A., Wang, Y., Wang, Y., Xu, X. and Li, W. 2017. Probiotic Bacillus amyloliquefaciens SC06 induces autophagy to protect against pathogens in macrophages. Frontiers in Microbiology 8: 469.
38. Yang, F., Wang, A., Zeng, X., Hou, C., Liu, H. and Qiao, S., 2015. Lactobacillus reuteri I5007 modulates tight junction protein expression in IPEC-J2 cells with LPS stimulation and in newborn piglets under normal conditions. BMC Microbiology 15: 32.
39. Zanello, G., Berri, M., Dupont, J., Sizaret, P.Y., D'Inca, R., Salmon, H. and Meurens, F., 2011. Saccharomyces cerevisiae modulates immune gene expressions and inhibits ETEC-mediated ERK1/2 and p38 signaling pathways in intestinal epithelial cells. PLoS One 6: 18573.
40. Zoumpopoulou, G., Foligne, B. and Christodoulou, K., 2008. Lactobacillus fermentum ACA-DC 179 displays probiotic potential in vitro and protects against trinitrobenzene sulfonic acid (TNBS)- induced colitis and Salmonella infection in murine models. International Journal of Food Microbiology 121: 18-26.