Anemia in hospitalized patients: an overlooked risk in medical care

Transfusion

Volumn 58, Issue 11, 2018, Pages 2522-2528

  Krishnasivam, Deepan ^a   Trentino, Kevin M ^b,d   Burrows, Sally ^c   Farmer, Shannon L ^d,e   Picardo, Sherman ^f   Leahy, Michael F ^g,h   Halder, Abir ^f   Chamberlain, Jenny ⁱ   Swain, Stuart ^j   Muthucumarana, Kalindu ^g   Waterer, Grant ^d  

^a After hours Unit (SAFE)   (Australia)

^b University of Western   (Australia)

^c School of Medicine   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e CURTIN UNIVERSITY   (Australia)

^f Department of Gastroenterology ^*  (Australia)

^g ROYAL PERTH HOSPITAL   (Australia)

^h UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁱ Paediatric Intensive Care Unit   (Australia)

^j HealthBench   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANEMIA; ARTICLE; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE TRANSFUSION; FEMALE; HOSPITAL ADMISSION; HOSPITAL MORTALITY; HOSPITAL PATIENT; HUMAN; INCIDENCE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; ODDS RATIO; OUTCOME ASSESSMENT; PREVALENCE; RETROSPECTIVE STUDY; RISK ASSESSMENT; TERTIARY CARE CENTER; VERY ELDERLY; WESTERN AUSTRALIA; HOSPITALIZATION; MIDDLE AGED; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; AGED, 80 AND OVER; ANEMIA; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; ODDS RATIO; RETROSPECTIVE STUDIES;

EID: 85054186329     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/trf.14877     Document Type: Article

References (35)

1. Kassebaum NJ, GBD 2013 Anemia Collaborators. The global burden of anemia. Hematol Oncol Clin North Am 2016;30:247-308
2. Martin ND, Scantling D. Hospital-acquired anemia: a contemporary review of etiologies and prevention strategies. J Infus Nurs 2015;38:330-8
3. Musallam KM, Tamim HM, Richards T, et al. Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet 2011;378:1396-407
4. National Blood Authority (Australia). Patient Blood Management Guidelines: Module 2 - Perioperative 2012 [cited Oct 2012]. Available
5. Li Z, Zhou T, Li Y, et al. Anemia increases the mortality risk in patients with stroke: a meta-analysis of cohort studies. Sci Rep 2016;6:26636
6. Martinez-Rivera C, Portillo K, Munoz-Ferrer A, et al. Anemia is a mortality predictor in hospitalized patients for COPD exacerbation. COPD 2012;9:243-50
7. Nissenson AR, Wade S, Goodnough T, et al. Economic burden of anemia in an insured population. J Manag Care Pharm 2005;11:565-74
8. Trentino KM, Farmer SL, Swain SG, et al. Increased hospital costs associated with red blood cell transfusion. Transfusion 2015;55:1082-9
9. Ferraris VA, Davenport DL, Saha SP, et al. Surgical outcomes and transfusion of minimal amounts of blood in the operating room. Arch Surg 2012;147:49-55
10. Whitlock EL, Kim H, Auerbach AD. Harms associated with single unit perioperative transfusion: retrospective population based analysis. BMJ 2015;350:h3037
11. Calderaro D, Gualandro DM, Caramelli B. Perioperative anemia: how low can we tolerate? JAMA Surg 2016;151:395-6
12. Kougias P, Orcutt S, Pak T, et al. Impact of postoperative nadir hemoglobin and blood transfusion on outcomes after operations for atherosclerotic vascular disease. J Vasc Surg 2013;57:1331-7
13. Quan H, Sundararajan V, Halfon P, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 2005;43:1130-9
14. Fowler AJ, Ahmad T, Phull MK, et al. Meta-analysis of the association between preoperative anaemia and mortality after surgery. Br J Surg 2015;102:1314-24
15. Karkouti K, Wijeysundera DN, Beattie WS. Reducing bleeding in cardiac surgery I. Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study. Circulation 2008;117:478-84
16. Koch CG, Li L, Sun Z, et al. Magnitude of anemia at discharge increases 30-day hospital readmissions. J Patient Saf 2017;13:202-6
17. Koch CG, Li L, Sun Z, et al. From bad to worse: anemia on admission and hospital-acquired anemia. J Patient Saf 2017;13:211-6
18. Kwok CS, Tiong D, Pradhan A, et al. Meta-analysis of the prognostic impact of anemia in patients undergoing percutaneous coronary intervention. Am J Cardiol 2016;118:610-20
19. Salisbury AC, Amin AP, Reid KJ, et al. Hospital-acquired anemia and in-hospital mortality in patients with acute myocardial infarction. Am Heart J 2011;162:300-9.e3
20. Isbister JP. The contracted plasma volume syndromes (relative polycythaemias) and their haemorheological significance. Baillieres Clin Haematol 1987;1:665-93
21. Le CH. The prevalence of anemia and moderate-severe anemia in the US population (NHANES 2003-2012). PLoS One 2016;11:e0166635
22. Riva E, Tettamanti M, Mosconi P, et al. Association of mild anemia with hospitalization and mortality in the elderly: the health and anemia population-based study. Haematologica 2009;94:22-8
23. Maiden MJ, Finnis ME, Peake S, et al. Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial. Crit Care 2018;22:118
24. Goodnough LT. Iron deficiency syndromes and iron-restricted erythropoiesis (CME). Transfusion 2012;52:1584-92
25. Pasricha SR, Flecknoe-Brown SC, Allen KJ, et al. Diagnosis and management of iron deficiency anaemia: a clinical update. Med J Aust 2010;193:525-32
26. Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005;352:1011-23
27. Leahy MF, Hofmann A, Towler S, et al. Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals. Transfusion 2017;57:1582-7
28. Faraoni D, DiNardo JA, Goobie SM. Relationship between preoperative anemia and in-hospital mortality in children undergoing noncardiac surgery. Anesth Analg 2016;123:1582-7
29. Shander A, Javidroozi M, Ozawa S, et al. What is really dangerous: anaemia or transfusion? Br J Anaesth 2011;107(Suppl 1):i41-59
30. Ranucci M, Baryshnikova E, Castelvecchio S, et al. Major bleeding, transfusions, and anemia: the deadly triad of cardiac surgery. Ann Thorac Surg 2013;96:478-85
31. Holcomb JB. Minimal transfusions: comment on "Surgical outcomes and transfusion of minimal amounts of blood in the operating room". Arch Surg 2012;147:55-6
32. Shander A. Financial and clinical outcomes associated with surgical bleeding complications. Surgery 2007;142(4 Suppl):S20-5
33. Munoz M, Gomez-Ramirez S, Kozek-Langeneker S, et al. 'Fit to Fly': overcoming barriers to preoperative haemoglobin optimization in surgical patients. BJA 2015;115:15-24
34. Zarychanski R, Houston DS. Anemia of chronic disease: a harmful disorder or an adaptive, beneficial response? CMAJ 2008;179:333-7
35. Fraenkel PG. Anemia of inflammation: a review. Med Clin North Am 2017;101:285-96