The challenge of liposome targeting in vivo

Liposome Technology Volume III: Targeted Drug Delivery and Biological Interaction

Volumn , Issue , 2018, Pages 1-28

  Poste, George ^a   Kirsh, Richard ^b   Koestler, Thomas ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85053093423     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9781351074117     Document Type: Chapter

References (80)

1. Poste, G., Liposome targeting in vivo: problems and opportunities, in Liposomes In Vivo. Supplement to Biologie Cellulaire, Nicolau, C., and Poste, G., Eds., in press.
2. Ehrlich, P., Collected SlUdies on lmmunitr, Vol. 2, Reprinted, Wiley and Sons, New York, 1906, 442.
3. Bundgaard, M., Bagger Hansen, A., and Kofod, H., Eds., Optimization of Drug Delivery, Alfred Benzon Symposium No. 17, Munksgaard, Copenhagen. 1982.
4. Gregoriadis, G. and Allison, A. C., Eds., Liposomes in Biological Systems, John Wiley and Sons, New York, 1980.
5. Kaye, S. B., Liposomes- problems and promise a; selective drug carriers, Cancer Treat. Rev., 8, 27, 1981.
6. Anon., Drug delivery aims for a bull's eye, High Technol., 2, 81, 1982.
7. Poste, G., The interaction of lipid vesicles (liposomes) with cultured cells and their use as carriers for drugs and macromolecules, in Liposomes in Biological Systems, Gregoriadis, G. and Allison, A. C., Eds., John Wiley and Sons, New York, 1980, 101.
8. Poste, G., Bucana, C., Raz, A., Bugelski, P., Kirsh, R., and Fidler, I. J, Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery, Cancer Res., 42, 1412, 1982.
9. Senior, J, and Gregoriadis, G., Stability of small unilamellar liposomes in serum and clearance from the circulation: the effect of the phospholipid and cholesterol components, Life Sci., 30, 2123, 1982.
10. Weiss, L. and Greep, R. O., Histology, 4th ed., McGraw-Hill, San Francisco, 1977. 11
11. Altura, B. M., Reticuloendothelial cells and host defence, Adv. Microcirc., 9, 252, 1980.
12. Motta, P. and Makable, S., Foetal and adult liver sinusoids and Kupffer cells as revealed by scanning electron microscopy, in The Reticuloendothelial System and the Pathogenesis of Liver Disease, Liehr, H. and Grun, M., Eds., Elsevier, Amsterdam, 1980, 11.
13. Crone, C., Adriadne's thread - an autobiographical essay on capillary permeability, Microvm Res., 20,133,1980.
14. Dawson, C.A., Linehan, J.H., and Rickahy, D.A., Pulmonary microcirculatory dynamics, Ann. N.Y. Acad. Sci., 384, 90, 1982.
15. Wolff, J.R., Ultrastructure of the terminal vascular bed as related to function, in Microcirculation, Vol. 1, Kaley, G. and Altura, B.M., Eds., Cniversity Park Press, Baltimore, 1977, 95.
16. Paaske, W.P., Capillary permeability in skeletal muscle, Acta Physiol. Scand., 101, I, 1977.
17. Gabbiani, G. and Majno, G., Pathophysiology of small vessel permeability, in Microcirculation, Vul.3, Kaley, G. and Altura, B. M., Eds., University Park Press, Baltimore, 1980, 143.
18. Bundgaard, M., Transport pathways in capillaries- in search of pores, Ann. Rev. Physiol., 42, 325, 1980.
19. Paste, G., Kirsh, R., Koestler, T., Bugelski, P., and Lewis, H., Analysis of the interaction ofliposomes with mononuclear phagocytes in the liver, spleen and bone marrow, submitted for publication.
20. Poste, G., Kirsh, R., and Lewis, H., The effect of repeated long-term intravenous administration of liposomes on the reticuloendothelial system, submitted for publication.
21. Scherphof, G. L., Interaction of liposomes with biological fluids and fate of liposomes in vivo, in Liposome Methodology. Leserman. L. D. and Barbel, J., Eds., Inserm, Paris, 1982, 79.
22. Roerdink, F., Diikstra, J, Hartman, G., Bolscher, B., and Scherphof, G., The involvement of parenchymal, Kupffer and endothelial liver cells in the hepatic uptake of intravenously injected liposomes. Effects of lanthanum and gadolinium salts, Biochim. Biophys. Acta, 667, 79, 1981.
23. Abra, R. M. and Hunt, C. A., Liposomcs disposition in vivo. Ill. Dose and vesicle-size effects, Biochim. Biophys. Acta, 666, 493, 1981.
24. Abra, R. M. and Hunt, C. A., Liposome disposition in vivo. IV. The interaction of sequential doses of liposomes having different diameters. Res. Comm. Chern. Pathol. Pharmacal., 36, 17, 1982.
25. Abra, R. M., Bosworth, M. E., and Hunt, C. A., Liposome disposition in vivo: effects of pre-dosing with liposomes, Res. Comm. Chern. Pathol. Pharmacal., 29, 349, 1980.
26. Freise, J, Muller, W. H., and Magerstedt, P., Uptake of liposomes and sheep red blood cells by the liver and spleen of rats with normal or decreased function of the reticuloendothelial system, Exp. Med., 178, 263, 1981.
27. Kao, Y. J, and Juliano, R. L., Interactions of liposomes with the reticuloendothelial system. Effects of reticuloendothelial blockade on the clearance of large unilamellar vesicles, Biochim. Biophys. Acta, 677, 453, 1981.
28. Bosworth, M. E. and Hunt, C. A., Liposome disposition in vivo. II. Dose dependency, J. Phnrm. Sci., 71, 100, 1982.
29. Ellens, H., Mayhew, E., and Rustum, Y. M., Reversible depression <>f the reticuloendothelial system by liposomes, Biochim. Biophys. Acta, 714, 479, 1982.
30. Souhami, R. L., Patel, H. M., and Ryman, B. E., The effect of reticuloendothelial blockade on the blood clearance and tissue distribution of liposomcs, Bimhim. BiophYs. Acta. 674, 354, 1981
31. Poste, G., Experimental systems for analysis of the malignant phenotype, Cancer Met. Rev., 1, 141, 1982.
32. Carr, I. and Daems, W. T., Eds., The Reticuloendothelial System: A Comprehensive Treatise. Vol. 1, Plenum Press,:New York, 1980.
33. Fidler, I. J. and Poste, G., Functional activity of macrophages in vivo: destruction of micrometastases, in Manual of Macrophaf?e Methodology. Herscowitz, H. B., Holden, H. T., Bellanti, J. A., and Ghaffcr, A., Eds., Marcel Dekker. New York, 1981, 431.
34. Fidler, I. J. and Poste, G., Treatment of spontaneous murine metastases hy the systemic administration of liposomes containing macrophage·activating agents, in Cancer: Achievements, Challenges and Prospects forthe 1980's, Burchenall, J. H. and Oettgen, H. F., Eds., Grune and Stratton, New York, Vol. 2, 1981, 77.
35. Fidler, I. J, Raz, A., Fogler, W. E., Kirsh, R., Bugelski, P., and Poste, G., Design of liposomes to improve delivery of macrophage-augmenting agents to alveolar macrophages, Cancer Res., 40, 4460, 1980.
36. Fidler, I. J., Raz, A., Fogler, W. E., Hoyer, L. C., and Postc, G., The role of plasma membrane receptors and the kinetics of macrophage activation by lymphokincs encapsulated in liposomes, Cancer Res., 41, 495, 1981.
37. Fidler, L J., Barnes, Z., Fogler, W E., Kirsh, R., Bugelski, P., and Poste, G., Involvement of rnacrophages in the eradication of estabJished metastases following intravenous injection of liposomes containing macrophage activators, Cancer Res., 42, 496, 1982.
38. Poste, G. and Fidler, I. J, Stimulation of macrophage-mediated destruction of lung metastases by administration of immunomodulators encapsulated in liposomes, in Liposomes, Drugs and Immunocompetent Cell Functions, Nicolau, C. and Paraf, A., Eds., Academic Press, New York, 1981, 147.
39. Poste, G. and Fidler, I. J, Active non-specific immunotherapy of lung metastases by macrophage activating agents encapsulated in liposomes, in Optimization of Drug Delivery, Aljred Benzon Symposium No. H. Bundgaard, H., Bagger Hansen, A., and Kofod, H., Eds., Munksgaard, Copenhagen, 1982, 418.
40. Poste, G. and Kirsh, R., Rapid decay of tumoricidal activity and loss of responsiveness to lymphokines in inflammatory macrophages, Cancer Res., 39, 2582, 1979.
41. Poste, G., Kirsh, R., Fogler, W., and Fidler, L.I., Activation of tumoricidal propenies in mouse macrophages by lymphokines encapsulated in liposomes, Cancer Res.. 39, 881, 1979.
42. Poste, G., Kirsh, R., Raz, A., Sone, S., Bucana, C., Fogler, W. E., and Fidler, I. J., Activation of tumoricidal propenies in macrophages by liposome-encapsulated lymphokines: in-vitro studies, in Liposomes in lmmunobiology, Tom, B. and Six, H., Eds., Elsevier, Amsterdam, 1980, 93.
43. Liehr, H. and Grun, M., Eds., The Reticuloendothelial Srstem and the Pathogenesis of Liver Disease, Elsevier, Amsterdam, 1980.
44. Alving, C. R. and Steck, E. A., The use of liposome-encapsulated drugs in leishmaniasis, Trends Biochem. Sci., 4, N175, 1979.
45. New, R. R. C., Antileishmanial activity of amphotericin and other antifungal agents entrapped in liposomes, J. Antimicrob. Chemother., 8, 371, 1981.
46. New, R. R. C., Chance, M. L., and Heath, S., The treatment of experimental cutaneous leishmaniasis with liposome-entrapped Pentostam, Parasitology, 83, 519, 1981.
47. Fountain, M. W., Dees, C., and Schultz, R. D., Enhanced intracellular killing of Staphylococcus aureus by canine monocytes treated with liposomes containing amikacin, gentamicin, kanamycin, and tobramycin, Curr. Microbial., 6, 373, 1981.
48. Taylor, R. L., Williams, D. M., Craven, P. C., Graybill, J. R., Drutz, D. J., and Magee, W. E., Amphotericin Bin liposomes: a novel therapy for histoplasmosis, Am. Rev. Respir. Dis., 125, 610, 1982.
49. Rahman, Y. E., Rosenthal, M. W., and Cerny, E. A., Intracellular plutonium: removal by liposome· encapsulated chelating agent, Science, 108, 300, 1973.
50. Lau, E. H., Cerny, E. A., and Rahman, Y. E., Liposome-encapsulated desferrioxamine in experimental iron overload, Br. J. Haematol., 47, 505, 1981.
51. Ahn, Y. S. and Harrington, W. J, Clinical uses of macrophage inhibitors, Adv. Int. Med., 25, 453, 1980.
52. Hart, I. R., Fogler, W. E., Poste, G., and Fidler, I. J, Toxicity studies of liposome-encapsulated immunomodulators administered intravenously to dogs and mice, Canar Immunol. Jmmunother., 10, 157, 1981.
53. Kennett, R. H., McKearn, T. J, and Bechtol, K. B., Eds., Monoclonal Antibodies, Plenum Press, New York, 1980.
54. Greaves, M., Delia, D., Sutherland, R., Rao, J., Verbi, W., Kemshead, J., Hariri, G., Goldstein, G., and Kung, P., Expression of the OKT monoclonal antibody defined antigenic determinants in malignancy, Int. J. lmmunopharmacol., 3, 283, 1981.
55. Youle, R. J. and Neville, D. M., Anti·Thy 1.2 monoclonal antibody linked to ricin is a potent cell-typespecific toxin, Proc. Nutl. Acad. Sci. U.S.A., 77, 5483, 1980.
56. Raso, V., Ritz, J., Basala, M., and Schlossman, S. T., Monoclonal antibody-ricin A chain conjugate selectively cytotoxic for cells bearing the common acute l'mphohlastic leukemia ant1gcn, Cancer Res., 42, 457, 1982.
57. Cosimi, A. B., Colvin, R. B., Burton, R. C., Rubin, R. H., Goldstein, G., Kung, P. C., Hansen, W. P., Delmonico, F. L., and Russell, P. S., Use of monoclonal antibodies toT-cell subsets for immunologic monitoring and treatment in recipients of renal allografts, N. Engl. J. Med., 305, 308, 1981.
58. Machy, P., Barbel, J, and Leserman, L. D., Differential endocytosis ofT and B lymphocyte surface molecules evaluated with antibody-bearing fluorescent liposomes containing methotrexate, Proc. Natl. A cad. Sci. U.SA., 79, 4148, 1982.
59. Andersen, R. G. W., Cell surface membrane structure and the function of endothehal cells, in Structure and Functionol the Circulation, Vol. 3, Schwartz, C. I. Werthessen, N. T.. Wolf, S., Eds., Plenum Press, New York, 1981, 239.
60. Lee, H. M., Waldrep, J C., Mandez-Picon, G., and Mohanakumar, T., Antibodies eluted from rejected human renal allografts: specificity to B lymphocytes, monocytes, primary kidney cells and endothelial cells, in Transplantation Today, Monaco, A. P., Wood, M. L., and Rapoport, F. T., Eds., Grunc and Stratton, New York, 1981, 108.
61. Ghandour, S., Lingley, K., Gombos, G., Hirn, M., Hirsch, M.-R., and Goridis, C., A surface marker for murine vascular endothelial cells defined by monoclonal antibody, j. Histochem. Cvrochem., 30, 165, 1982.
62. Nakatsu, K. and Cameron, D. A., Uptake ofliposome-entrapped mannitol by diaphragm, Can. J. Physiol. Pharmacol., 57, 756, 1979.
63. Ellens, H., Morselt, H., and Scherphof, G., In-vivo of large unilamcllar sphingomyelin-cholesterol liposomes after intraperitoneal and intravenous injection into rats, Biochim. Biophys. Acta, 674, 10, 1981
64. Parker, R. J, Sieber, S. M., and Weinstein, J. N., Effect of liposome encapsulation of a fluorescent dye on its uptake by the lymphatics of the rat, Pharmacologv. 23, 128, 1981.
65. Rusznyak, I., Foldi, M., and Szabo, G., Lymphatics and Lymph Circulmion, 2nd ed., Pergamon Press, New York, 1967, 155.
66. Casley-Smith, J.R., Lymphand lymphatics, in Microcirculation. Vol. I, Kaley, G. and Altura, B.~., Eds., University Park Press, Baltimore, 1977, 423.
67. Segal, A. W., Gregoriadis, G., and Black, C. D. V., Liposomes as vehicles for the local release of drugs, Clin. Sci. Mol. Med., 49, 99, 1975.
68. Shinozawa, S., Araki, Y., and Oda, T., Distribution of -'H-prednisolone entrapped in lipid layer of liposome after intramuscular administration in rats, Res. Comm. Chern. Mathol. Pharmacal., 24, 223, 1979.
69. Jackson A. J., The effect of route of administration on the disposition of inulin encapsulated in multi lamellar vesicles of defined particle size, Res. Comm. Chem. Pathol. Pharmacol., 27, 293, 1980.
70. Khato, J., Priester, E. R., and Sieber, S. M., Enhanced lymph node uptake of melphalan following iiposomal entrapment and effects on lymph node metastasis in rats, Cancer Treat. Rep. 66 517, 1982.
71. Richardson, V. J., Ryman, B. E., Jewkes, R. F., Jeyasingh, K., Tattersall, M. N.H., Newlands, E. S., and Kaye, S. B., Tissue distribution and tumor localization of 99m-technetium-labelled liposomes in cancer patients, Br. J. Cancer, 40, 35, 1979.
72. Peterson, H.-I., Tumor Blood Circulation, CRC Press, Boca Raton, 1979.
73. Poste, G. and Fidler, I. J, The pathogenesis of cancer metastasis. Nature (London), 283, 139, 1980.
74. Pimm, M. V., Embleton, M. J, and Baldwin, R. W., Multiple antigenic specificities within primary 3-methylcholanthrenc-induced rat sarcomas and metastases, Int..J. Cancer, 25, 621, 1980.
75. Albino, A. P., Lloyd, K. O., Houghton, A. N., Oettgen, H. F., and Old, L. J., Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient, J. Exp. Med., 154, 1764, 1981.
76. Mazauric, T., Mitchell, K. F., Letchworth, G. J., III, Koprowski, H., and Steplewski, Z., Monoclonal antibody-defined human lung cell surface protein antigens, Cancer Res., 42, 150, 1982.
77. Staub, N. C., Bland, R. D., Brigham, K. L., Demling, R., Erdmann, J. A., and Woolverton, W. C., Preparation of chronic lung fistulas in sheep, J. Surg. Res., 19, 315, 1975.
78. Murota, S. and lkuo, M., Effect of prostaglandin 1, and related compounds on vascular permeability response in granuloma tissues, Prostuxlandins, 15, 297, 1978.
79. Poste, G., Kirsh, R., and Koestler, T., unpublished observations.
80. Poste, G., unpublished observations.