Neurophysiological basis and clinical applications of the H-reflex as an adjunct for evaluating response to intrathecal baclofen for spasticity

Acta Neurochirurgica, Supplementum

Volumn , Issue 97 PART 1, 2007, Pages 231-241

  Stokic, Dobrivoje S ^a   Yablon, S A ^a  

^a METHODIST REHABILITATION CENTER   (United States)

Author keywords

Baclofen; brain; H reflex; injury; intrathecal drug infusion; spasticity; spinal cord

Indexed keywords

BACLOFEN; CENTRAL MUSCLE RELAXANT;

DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECT; EVALUATION; HOFFMANN REFLEX; HUMAN; PATHOPHYSIOLOGY; REVIEW; SPASTICITY;

BACLOFEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; H-REFLEX; HUMANS; MUSCLE RELAXANTS, CENTRAL; MUSCLE SPASTICITY;

EID: 85052609469     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-211-33079-1_32     Document Type: Review

References (29)

1. Akman MN, Loubser PG, Donovan WH, O'Neill ME, Rossi CD (1993) Intrathecal baclofen: does tolerance occur? Paraplegia 31:516-520
2. Azouvi P, Roby-Brami A, Biraben A, Thiebaut JB, Thurel C, Bussel B (1993) Effect of intrathecal baclofen on the monosynaptic reflex in humans: evidence for a postsynaptic action. J Neurol Neurosurg Psychiatry 56:515-519
3. Becher JG, Lankhorst GJ, van Bennekom CA, Vogelaar TW (1999) Measurement of the effect of a bolus dose of intrathecal baclofen by a repetitive movement test. J Neurol 246:1080-1085
4. Christie A, Lester S, La Pierre D, Gabriel DA (2004) Reliability of a new measure of H-reflex excitability. Clin Neurophysiol 115:116-123
5. Dachy B, Dan B (2002) Electrophysiological assessment of the effect of intrathecal baclofen in spastic children. Clin Neurophysiol 113:336-340
6. Dawes WJ, Drake JM, Fehlings D (2003) Microfracture of a baclofen pump catheter with intermittent under-and overdose. Pediatr Neurosurg 39:144-148
7. Detrembleur C, Plaghki L (2000) Quantitative assessment of intrathecally administered baclofen in spasticity. Arch Phys Med Rehabil 81:279-284
8. Galiana L, Fung J, Kearney R (2005) Identification of intrinsic and reflex ankle stiffness components in stroke patients. Exp Brain Res 165:422-434
9. Latash ML, Penn RD, Corcos DM, Gottlieb GL (1989) Short-term effects of intrathecal baclofen in spasticity. Exp Neurol 103:165-172
10. Lazorthes Y, Sallerin-Caute B, Verdie JC, Bastide R, Carillo JP (1990) Chronic intrathecal baclofen administration for control of severe spasticity. J Neurosurg 72:393-402
11. Levin MF, Hui-Chan C (1993) Are H and stretch reflexes in hemiparesis reproducible and correlated with spasticity? J Neurol 240:63-71
12. Lew SM, Psaty EL, Abbott R (2005) An unusual cause of overdose after baclofen pump implantation: case report. Neurosurgery 56: E624
13. Lexell JE, Downham DY (2005) How to assess the reliability of measurements in rehabilitation. Am J Phys Med Rehabil 84:719-723
14. Macdonell RA, Talalla A, Swash M, Grundy D (1989) Intrathecal baclofen and the H-reflex. J Neurol Neurosurg Psychiatry 52:1110-1112
15. Misiaszek JE (2003) The H-reflex as a tool in neurophysiology: its limitations and uses in understanding nervous system function. Muscle Nerve 28:144-160
16. Morris S (2002) Ashworth and Tardieu scales: their clinical relevance for measuring spasticity in adult and paediatric neurological populations. Physical Therapy Reviews 7:53-62
17. Nielsen JF, Hansen HJ, Sunde N, Christensen JJ (2002) Evidence of tolerance to baclofen in treatment of severe spasticity with intrathecal baclofen. Clin Neurol Neurosurg 104:142-145
18. Nielsen JF, Sinkjaer T (1996) A comparison of clinical and laboratory measures of spasticity. Mult Scler 1:296-301
19. Orsnes G, Crone C, Krarup C, Petersen N, Nielsen J (2000) The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. Clin Neurophysiol 111:1372-1379
20. Pandyan AD, Johnson GR, Price CI, Curless RH, Barnes MP, Rodgers H (1999) A review of the properties and limitations of the Ashworth and modified Ashworth scales as measures of spasticity. Clin Rehabil 13:373-383
21. Pohl M, Rockstroh G, Ruckriem S, Mehrholz J, Pause M, Koch R, Strik H (2003) Time course of the effect of a bolus dose of intrathecal baclofen on severe cerebral spasticity. J Neurol 250:1195-1200
22. Sallerin-Caute B, Lazorthes Y, Monsarrat B, Cros J, Bastide R (1991) CSF baclofen levels after intrathecal administration in severe spasticity. Eur J Clin Pharmacol 40:363-365
23. Schurch B (1993) Errors and limitations of the multimodality checking methods of defective spinal intrathecal pump systems. Case report. Paraplegia 31:611-615
24. Sinkjaer T, Magnussen I (1994) Passive, intrinsic and reflexmediated stiffness in the ankle extensors of hemiparetic patients. Brain 117:355-363
25. Soni BM, Mani RM, Oo T, Vaidyanathan S (2003) Treatment of spasticity in a spinal cord-injured patient with intrathecal morphine due to intrathecal baclofen tolerance-a case report and review of literature. Spinal Cord 41:586-589
26. Stokic DS, Yablon SA, Hayes A (2005) Comparison of clinical and neurophysiologic responses to intrathecal baclofen bolus administration in moderate-to-severe spasticity after acquired brain injury. Arch Phys Med Rehabil 86:1801-1806
27. Stokic DS, Yablon SA, Hayes A, Vesovic-Potic V, Olivier J (2006) Dose-response relationship between the H-reflex and continuous intrathecal baclofen administration for anagement of spasticity. Clin Neurophysiol 117:1283-1289
28. Uyttenboogaart M, Stewart RE, Vroomen PC, De Keyser J, Luijckx GJ (2005) Optimizing cutoff scores for the Barthel index and the modified Rankin scale for defining outcome in acute stroke trials. Stroke 36:1984-1987
29. Yablon SA, Stokic DS (2004) Neurophysiologic evaluation of spastic hypertonia: implications for management of the patient with the intrathecal baclofen pump. Am J Phys Med Rehabil 83: S10-S18