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Volumn 110, Issue , 2011, Pages 147-150

Clazosentan: Prevention of cerebral vasospasm and the potential to overcome infarction

Author keywords

Aneurysmal subarachnoid hemorrhage; Cerebral vasospasm; Clazosentan; CONSCIOUS 1 study

Indexed keywords

CLAZOSENTAN; NIMODIPINE; PLACEBO;

EID: 85052608970     PISSN: 00651419     EISSN: 00016268     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0356-2_26     Document Type: Conference Paper
Times cited : (6)

References (10)
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  • 2
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    • New insights into the causes and therapy of cerebral vasospasm following subarachnoid hemorrhage
    • Crowley RW, Medel R, Kassell NF, Dumont AS. New insights into the causes and therapy of cerebral vasospasm following subarachnoid hemorrhage. Drug Discov Today. 2008;13:254-260
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    • Crowley, R.W.1    Medel, R.2    Kassell, N.F.3    Dumont, A.S.4
  • 3
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    • Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage
    • Keyrouz SG, Diringer MN. Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage. Critical Care. 2007;11:220
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    • Keyrouz, S.G.1    Diringer, M.N.2
  • 5
    • 34248524672 scopus 로고    scopus 로고
    • Cerebral vasospasm after subarachnoid hemorrhage: The emerging revolution
    • Macdonald RL, Pluta RM, Zhang JH. Cerebral vasospasm after subarachnoid hemorrhage: The emerging revolution. Nat Clin Pract Neurol. 2007;3:256-263
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    • Macdonald, R.L.1    Pluta, R.M.2    Zhang, J.H.3
  • 6
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    • Conscious-1 investigators clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (conscious-1): Randomized double-Blind placebo-controlled phase 2 dose-finding trial
    • Macdonald RL, Kassell NF, Mayer S, Ruefenacht D, Schmiedek P, Weidauer S, et al.; CONSCIOUS-1 Investigators. Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): Randomized, double-Blind, placebo-controlled phase 2 dose-finding trial. Stroke 2008;39:3015-3021
    • (2008) Stroke , vol.39 , pp. 3015-3021
    • Macdonald, R.L.1    Kassell, N.F.2    Mayer, S.3    Ruefenacht, D.4    Schmiedek, P.5    Weidauer, S.6
  • 8
    • 24944512347 scopus 로고    scopus 로고
    • Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: Results of a randomized, double-Blind, placebo-controlled, multicenter phase IIa study
    • Vajkoczy P, Meyer B, Weidauer S, Raabe A, Thome C, Ringel F, et al. Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: Results of a randomized, double-Blind, placebo-controlled, multicenter phase IIa study. J Neurosurg. 2005;103:9-17
    • (2005) J Neurosurg , vol.103 , pp. 9-17
    • Vajkoczy, P.1    Meyer, B.2    Weidauer, S.3    Raabe, A.4    Thome, C.5    Ringel, F.6
  • 9
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    • Influence of ethnic origin and sex on the pharmacokinetics of clazosentan
    • van Giersbergen PL, Gunawardena KA, Dingemanse J. Influence of ethnic origin and sex on the pharmacokinetics of clazosentan. J Clin Pharmacol. 2007;47:1374-1380
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    • Impairment of cerebral perfusion and infarct patterns attributable to vasospasm after aneurysmal subarachnoid hemorrhage
    • Weidauer S, Lanfermann H, Raabe A, Zanella F, Seifert V, Beck J. Impairment of cerebral perfusion and infarct patterns attributable to vasospasm after aneurysmal subarachnoid hemorrhage. Stroke. 2007;38:1831-1836
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    • Weidauer, S.1    Lanfermann, H.2    Raabe, A.3    Zanella, F.4    Seifert, V.5    Beck, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.