Effect of dimethyl sulfoxide on blood-brain barrier integrity following middle cerebral artery occlusion in the rat

Acta Neurochirurgica, Supplementum

Volumn , Issue 96, 2006, Pages 258-262

  Kleindienst, A ^a   Dunbar, J G ^a   Glisson, R ^a   Okuno, K ^a   Marmarou, A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

blood brain barrier; brain edema; Dimethyl sulfoxide; Evans blue extravasation; middle cerebral artery occlusion

Indexed keywords

DIMETHYL SULFOXIDE;

ANIMAL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; CEREBRAL ARTERY DISEASE; DOSE RESPONSE; DRUG EFFECT; MALE; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; DIMETHYL SULFOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85052608946     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-211-30714-1_55     Document Type: Article

References (19)

1. Beaumont A, Marmarou A, Hayasaki K, Barzo P, Fatouros P, Corwin F, Marmarou C, Dunbar J (2000) The permissive nature of blood brain barrier (BBB) opening in edema formation following traumatic brain injury. Acta Neurochir [Suppl] 76:125-129
2. Belayev L, Alonso OF, Busto R, Zhao W, Ginsberg MD (1996) Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 27:1616-1623
3. Brink JJ, Stein DG (1967) Pemoline levels in brain: enhancement by dimethyl sulfoxide. Science 158:1479-1480
4. Broadwell RD, Salcman M, Kaplan RS (1982) Morphologic effect of dimethyl sulfoxide on the blood-brain barrier. Science 217:164-166
5. De La Torre JC (1970) Relative penetration of L-dopa and 5-HTP through the brain barrier using dimethyl sulfoxide. Experientia 26:1117-1118
6. De La Torre JC, Kawanaga HM, Johnson CM, Goode DJ, Kajihara K, Mullan S (1975) Dimethyl sulfoxide in central nervous system trauma. Ann N Y Acad Sci 243:362-389
7. Ginsberg MD, Becker DA, Busto R, Belayev A, Zhang Y, Khoutorova L, Ley JJ, Zhao W, Belayev L (2003) Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia. Ann Neurol 54:330-342
8. Gollan F (1967) Effect of DMSO and THAM on ionizing radiation in mice. Ann N Y Acad Sci 141:63-64
9. Gotoh O, Asano T, Koide T, Takakura K (1985) Ischemic brain edema following occlusion of the middle cerebral artery in the rat. I: The time courses of the brain water, sodium and potassium contents and blood-brain barrier permeability to 125I-albumin. Stroke 16:101-109
10. Greig NH, Sweeney DJ, Rapoport SI (1985) Inability of dimethyl sulfoxide to increase brain uptake of water-soluble compounds: implications to chemotherapy for brain tumors. Cancer Treat Rep 69:305-312
11. Johnson M, Jessup R, Ramwell PW (1974) The significance of protein disulfide and sulfhydryl groups in prostaglandin action. Prostaglandins 5:125-136
12. Kolb KH, Jaenicke G, Kramer M, Schulz PE (1967) Absorption, distribution and elimination of labeled dimethyl sulfoxide in man and animals. Ann N Y Acad Sci 141:85-95
13. Little JR, Cook A, Lesser RP (1981) Treatment of acute focal cerebral ischemia with dimethyl sulfoxide. Neurosurgery 9:34-39
14. Little JR, Spetzler RF, Roski RA, Selman WR, Zabramski J, Lesser RP (1983) Ineffectiveness of DMSO in treating experimental brain ischemia. Ann N Y Acad Sci 411:269-277
15. Loo DD, Zeuthen T, Chandy G, Wright EM (1996) Cotransport of water by the Na+/glucose cotransporter. Proc Natl Acad Sci U S A 93:13367-13370
16. Panganamala RV, Sharma HM, Heikkila E, Geer JC, Cornwell DG (1976) Role of hydroxyl radical scavengers dimethyl sulfoxide, alcohols and methional in the inhibition of prostaglandin biosynthesis. Prostaglandins 11:599-607
17. Rammler DH (1967) The effect of DMSO on several enzyme systems. Ann N Y Acad Sci 141:291-299
18. Ruigrok TJ, de Moes D, Slade AM, Nayler WG (1981) The effect of dimethylsulfoxide on the calcium paradox. Am J Pathol 103:390-403
19. Wright EM, Loo DD (2000) Coupling between Na+, sugar, and water transport across the intestine. Ann N Y Acad Sci 915:54-66