Reported direct and indirect contact with dromedary camels among laboratory-confirmed MERS-CoV cases

Viruses

Volumn 10, Issue 8, 2018, Pages

  Conzade, Romy ^a,b   Grant, Rebecca ^a,c   Malik, Mamunur Rahman ^a   Elkholy, Amgad ^a   Elhakim, Mohamed ^a   Samhouri, Dalia ^a   Ben Embarek, Peter K ^a   Van Kerkhove, Maria D ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c INSTITUT PASTEUR   (France)

Author keywords

Dromedary camels; MERS CoV; Zoonotic transmission

Indexed keywords

ARTICLE; DROMEDARY; HUMAN; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MILK; NONHUMAN; WORLD HEALTH ORGANIZATION; ADULT; AGED; ANIMAL; CAMEL; CORONAVIRUS INFECTION; DISEASE CARRIER; FEMALE; ISOLATION AND PURIFICATION; MALE; MIDDLE AGED; RETROSPECTIVE STUDY; SAUDI ARABIA; TRANSMISSION; VETERINARY MEDICINE; VIROLOGY; ZOONOSIS;

ADULT; AGED; ANIMALS; CAMELUS; CORONAVIRUS INFECTIONS; DISEASE RESERVOIRS; FEMALE; HUMANS; MALE; MIDDLE AGED; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; RETROSPECTIVE STUDIES; SAUDI ARABIA; WORLD HEALTH ORGANIZATION; ZOONOSES;

EID: 85052061506     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v10080425     Document Type: Article

References (48)

1. Zaki, A.M.; van Boheemen, S.; Bestebroer, T.M.; Osterhaus, A.D.; Fouchier, R.A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 2012, 367, 1814-1820.
2. WHO. WHO MERS-CoV Global Summary and Assessment of risk. 21 July 2017. Available online: http://www.who.int/emergencies/mers-cov/risk-assessment-july-2017.pdf?ua=1 (accessed on 30 July 2018).
3. Arwady, M.A.; Alraddadi, B.; Basler, C.; Azhar, E.I.; Abuelzein, E.; Sindy, A.I.; Sadiq, B.M.; Althaqafi, A.O.; Shabouni, O.; Banjar, A. et al. Middle East Respiratory Syndrome Coronavirus Transmission in Extended Family, Saudi Arabia, 2014. Emerg. Infect. Dis. 2016, 22, 1395-1402.
4. Hijawi, B.; Abdallat, M.; Sayaydeh, A.; Alqasrawi, S.; Haddadin, A.; Jaarour, N.; Alsheikh, S.; Alsanouri, T. Novel coronavirus infections in Jordan, April 2012: Epidemiological findings from a retrospective investigation. East. Mediterr. Health J. 2013, 19 (Suppl. 1), S12-S18.
5. Assiri, A.; McGeer, A.; Perl, T.M.; Price, C.S.; Al Rabeeah, A.A.; Cummings, D.A.; Alabdullatif, Z.N.; Assad, M.; Almulhim, A.; Makhdoom, H. et al. Hospital outbreak of Middle East respiratory syndrome coronavirus. N. Engl. J. Med. 2013, 369, 407-416.
6. Al-Abdallat, M.M.; Payne, D.C.; Alqasrawi, S.; Rha, B.; Tohme, R.A.; Abedi, G.R.; Al Nsour, M.; Iblan, I.; Jarour, N.; Farag, N.H. et al. Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: A serologic, epidemiologic, and clinical description. Clin. Infect. Dis. 2014, 59, 1225-1233.
7. Drosten, C.; Muth, D.; Corman, V.M.; Hussain, R.; Al Masri, M.; HajOmar, W.; Landt, O.; Assiri, A.; Eckerle, I.; Al Shangiti, A. et al. An observational, laboratory-based study of outbreaks of middle East respiratory syndrome coronavirus in Jeddah and Riyadh, kingdom of Saudi Arabia, 2014. Clin. Infect. Dis. 2015, 60, 369-377.
8. Al Hosani, F.I.; Pringle, K.; Al Mulla, M.; Kim, L.; Pham, H.; Alami, N.N.; Khudhair, A.; Hall, A.J.; Aden, B.; El Saleh, F. et al. Response to Emergence of Middle East Respiratory Syndrome Coronavirus, Abu Dhabi, United Arab Emirates, 2013-2014. Emerg. Infect. Dis. 2016, 22, 1162-1168.
9. Ki, M. 2015 MERS outbreak in Korea: Hospital-to-hospital transmission. Epidemiol. Health 2015, 37, e2015033.
10. Park, H.Y.; Lee, E.J.; Ryu, Y.W.; Kim, Y.; Kim, H.; Lee, H.; Yi, S.J. Epidemiological investigation of MERS-CoV spread in a single hospital in South Korea, May to June 2015. Euro Surveill. 2015, 20, 1-6.
11. Al-Tawfiq, J.A.; Auwaerter, P.G. Healthcare-associated Infections: The Hallmark of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) With Review of the Literature. J. Hosp. Infect. 2018.
12. Reusken, C.B.; Raj, V.S.; Koopmans, M.P.; Haagmans, B.L. Cross host transmission in the emergence of MERS coronavirus. Curr. Opin. Virol. 2016, 16, 55-62.
13. Wernery, U.; Corman, V.M.; Wong, E.Y.; Tsang, A.K.; Muth, D.; Lau, S.K.; Khazanehdari, K.; Zirkel, F.; Ali, M.; Nagy, P. et al. Acute middle East respiratory syndrome coronavirus infection in livestock Dromedaries, Dubai, 2014. Emerg. Infect. Dis. 2015, 21, 1019-1022.
14. Alagaili, A.N.; Briese, T.; Mishra, N.; Kapoor, V.; Sameroff, S.C.; Burbelo, P.D.; de Wit, E.; Munster, V.J.; Hensley, L.E.; Zalmout, I.S. et al. Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia. mBio 2014, 5, e01002-14.
15. Hemida, M.G.; Chu, D.K.; Poon, L.L.; Perera, R.A.; Alhammadi, M.A.; Ng, H.Y.; Siu, L.Y.; Guan, Y.; Alnaeem, A.; Peiris, M. MERS coronavirus in dromedary camel herd, Saudi Arabia. Emerg. Infect. Dis. 2014, 20, 1231-1234.
16. Chu, D.K.; Poon, L.L.; Gomaa, M.M.; Shehata, M.M.; Perera, R.A.; Abu Zeid, D.; El Rifay, A.S.; Siu, L.Y.; Guan, Y.; Webby, R.J. et al. MERS coronaviruses in dromedary camels, Egypt. Emerg. Infect. Dis. 2014, 20, 1049-1053.
17. Haagmans, B.L.; Al Dhahiry, S.H.; Reusken, C.B.; Raj, V.S.; Galiano, M.; Myers, R.; Godeke, G.J.; Jonges, M.; Farag, E.; Diab, A. et al. Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation. Lancet Infect. Dis. 2014, 14, 140-145.
18. Nowotny, N.; Kolodziejek, J. Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels, Oman, 2013. Euro Surveill. 2014, 19, 20781.
19. Raj, V.S.; Farag, E.A.; Reusken, C.B.; Lamers, M.M.; Pas, S.D.; Voermans, J.; Smits, S.L.; Osterhaus, A.D.; Al-Mawlawi, N.; Al-Romaihi, H.E. et al. Isolation of MERS coronavirus from a dromedary camel, Qatar, 2014. Emerg. Infect. Dis. 2014, 20, 1339-1342.
20. Adney, D.R.; van Doremalen, N.; Brown, V.R.; Bushmaker, T.; Scott, D.; de Wit, E.; Bowen, R.A.; Munster, V.J. Replication and shedding of MERS-CoV in upper respiratory tract of inoculated dromedary camels. Emerg. Infect. Dis. 2014, 20, 1999-2005.
21. Azhar, E.I.; El-Kafrawy, S.A.; Farraj, S.A.; Hassan, A.M.; Al-Saeed, M.S.; Hashem, A.M.; Madani, T.A. Evidence for camel-to-human transmission of MERS coronavirus. N. Engl. J. Med. 2014, 370, 2499-2505.
22. Memish, Z.A.; Cotten, M.; Meyer, B.; Watson, S.J.; Alsahafi, A.J.; Al Rabeeah, A.A.; Corman, V.M.; Sieberg, A.; Makhdoom, H.Q.; Assiri, A. et al. Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013. Emerg. Infect. Dis. 2014, 20, 1012-1015.
23. Drosten, C.; Kellam, P.; Memish, Z.A. Evidence for camel-to-human transmission of MERS coronavirus. N. Engl. J. Med. 2014, 371, 1359-1360.
24. Farag, E.A.; Reusken, C.B.; Haagmans, B.L.; Mohran, K.A.; Stalin Raj, V.; Pas, S.D.; Voermans, J.; Smits, S.L.; Godeke, G.J.; Al-Hajri, M.M. et al. High proportion of MERS-CoV shedding dromedaries at slaughterhouse with a potential epidemiological link to human cases, Qatar 2014. Infect. Ecol. Epidemiol. 2015, 5, 28305.
25. Hemida, M.G.; Perera, R.A.; Al Jassim, R.A.; Kayali, G.; Siu, L.Y.; Wang, P.; Chu, K.W.; Perlman, S.; Ali, M.A.; Alnaeem, A. et al. Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity. Euro Surveill. 2014, 19, 20828.
26. Miguel, E.; Chevalier, V.; Ayelet, G.; Ben Bencheikh, M.N.; Boussini, H.; Chu, D.K.; El Berbri, I.; Fassi-Fihri, O.; Faye, B.; Fekadu, G. et al. Risk factors for MERS coronavirus infection in dromedary camels in Burkina Faso, Ethiopia, and Morocco, 2015. Euro Surveill. 2017, 22, 30498.
27. Ali, M.; El-Shesheny, R.; Kandeil, A.; Shehata, M.; Elsokary, B.; Gomaa, M.; Hassan, N.; El Sayed, A.; El-Taweel, A.; Sobhy, H. et al. Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016. Euro Surveill. 2017, 22, 30487.
28. Reusken, C.B.; Ababneh, M.; Raj, V.S.; Meyer, B.; Eljarah, A.; Abutarbush, S.; Godeke, G.J.; Bestebroer, T.M.; Zutt, I.; Muller, M.A. et al. Middle East Respiratory Syndrome coronavirus (MERS-CoV) serology in major livestock species in an affected region in Jordan, June to September 2013. Euro Surveill. 2013, 18, 20662.
29. Van Doremalen, N.; Hijazeen, Z.S.; Holloway, P.; Al Omari, B.; McDowell, C.; Adney, D.; Talafha, H.A.; Guitian, J.; Steel, J.; Amarin, N. et al. High Prevalence of Middle East Respiratory Coronavirus in Young Dromedary Camels in Jordan. Vector Borne Zoonotic Dis. 2017, 17, 155-159.
30. Miguel, E.; Perera, R.A.; Baubekova, A.; Chevalier, V.; Faye, B.; Akhmetsadykov, N.; Ng, C.Y.; Roger, F.; Peiris, M. Absence of Middle East Respiratory Syndrome Coronavirus in Camelids, Kazakhstan, 2015. Emerg. Infect. Dis. 2016, 22, 555-557.
31. Corman, V.M.; Jores, J.; Meyer, B.; Younan, M.; Liljander, A.; Said, M.Y.; Gluecks, I.; Lattwein, E.; Bosch, B.J.; Drexler, J.F. et al. Antibodies against MERS coronavirus in dromedary camels, Kenya, 1992-2013. Emerg. Infect. Dis. 2014, 20, 1319-1322.
32. Hemida, M.G.; Al-Naeem, A.; Perera, R.A.; Chin, A.W.; Poon, L.L.; Peiris, M. Lack of middle East respiratory syndrome coronavirus transmission from infected camels. Emerg. Infect. Dis. 2015, 21, 699-701.
33. Falzarano, D.; Kamissoko, B.; de Wit, E.; Maiga, O.; Cronin, J.; Samake, K.; Traore, A.; Milne-Price, S.; Munster, V.J.; Sogoba, N. et al. Dromedary camels in northern Mali have high seropositivity to MERS-CoV. One Health 2017, 3, 41-43.
34. Reusken, C.B.; Messadi, L.; Feyisa, A.; Ularamu, H.; Godeke, G.J.; Danmarwa, A.; Dawo, F.; Jemli, M.; Melaku, S.; Shamaki, D. et al. Geographic distribution of MERS coronavirus among dromedary camels, Africa. Emerg. Infect. Dis. 2014, 20, 1370-1374.
35. Reusken, C.B.; Farag, E.A.; Jonges, M.; Godeke, G.J.; El-Sayed, A.M.; Pas, S.D.; Raj, V.S.; Mohran, K.A.; Moussa, H.A.; Ghobashy, H. et al. Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels, Qatar, April 2014. Euro Surveill. 2014, 19, 20829.
36. Saqib, M.; Sieberg, A.; Hussain, M.H.; Mansoor, M.K.; Zohaib, A.; Lattwein, E.; Muller, M.A.; Drosten, C.; Corman, V.M. Serologic Evidence for MERS-CoV Infection in Dromedary Camels, Punjab, Pakistan, 2012-2015. Emerg. Infect. Dis. 2017, 23, 550-551.
37. Muller, M.A.; Corman, V.M.; Jores, J.; Meyer, B.; Younan, M.; Liljander, A.; Bosch, B.J.; Lattwein, E.; Hilali, M.; Musa, B.E. et al. MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997. Emerg. Infect. Dis. 2014, 20, 2093-2095.
38. Muhairi, S.A.; Hosani, F.A.; Eltahir, Y.M.; Mulla, M.A.; Yusof, M.F.; Serhan, W.S.; Hashem, F.M.; Elsayed, E.A.; Marzoug, B.A.; Abdelazim, A.S. Epidemiological investigation of Middle East respiratory syndrome coronavirus in dromedary camel farms linked with human infection in Abu Dhabi Emirate, United Arab Emirates. Virus Genes 2016, 52, 848-854.
39. Gossner, C.; Danielson, N.; Gervelmeyer, A.; Berthe, F.; Faye, B.; Kaasik Aaslav, K.; Adlhoch, C.; Zeller, H.; Penttinen, P.; Coulombier, D. Human-Dromedary Camel Interactions and the Risk of Acquiring Zoonotic Middle East Respiratory Syndrome Coronavirus Infection. Zoonoses Public Health 2016, 63, 1-9.
40. Alraddadi, B.M.; Watson, J.T.; Almarashi, A.; Abedi, G.R.; Turkistani, A.; Sadran, M.; Housa, A.; Almazroa, M.A.; Alraihan, N.; Banjar, A. et al. Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014. Emerg. Infect. Dis. 2016, 22, 49-55.
41. Widagdo, W.; Okba, N.M.A.; Stalin Raj, V.; Haagmans, B.L. MERS-coronavirus: From discovery to intervention. One Health 2017, 3, 11-16.
42. WHO. Laboratory Testing for Middle East Respiratory Syndrome Coronavirus, Interim Guidance; WHO/MERS/LAB/15.1/Rev1/2018. Licence: CC BY-NC-SA 3.0 IGO; World Health Organization: Geneva, Switzerland, 2018. Available online: http://www.who.int/csr/disease/coronavirus_infections/merslaboratory-testing/en/(accessed on 30 July 2018).
43. Jiang, L.; Wang, N.; Zuo, T.; Shi, X.; Poon, K.M.; Wu, Y.; Gao, F.; Li, D.; Wang, R.; Guo, J. et al. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci. Transl. Med. 2014, 6, 234ra259.
44. WHO. Update on Mers-cov Transmission from Animals to Humans, and Interim Recommendations for At-Risk Groups: Updated on 26 January 2018. Available online: http://www.Who.Int/csr/disease/coronavirus_infections/transmission-and-recommendations/en/ (accessed on 30 July 2018).
45. Chu, D.K.W.; Hui, K.P.Y.; Perera, R.; Miguel, E.; Niemeyer, D.; Zhao, J.; Channappanavar, R.; Dudas, G.; Oladipo, J.O.; Traore, A. et al. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc. Natl. Acad. Sci. USA 2018, 115, 3144-3149.
46. Sikkema, R.S.; Farag, E.; Himatt, S.; Ibrahim, A.K.; Al-Romaihi, H.; Al-Marri, S.A.; Al-Thani, M.; El-Sayed, A.M.; Al-Hajri, M.; Haagmans, B.L. et al. Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Infection in Camel Workers in Qatar During 2013-2014: A Case-Control Study. J. Infect. Dis. 2017, 215, 1702-1705.
47. WHO. WHO Updated Guidance: Investigation of Cases of Human Infection with MERS-CoV, Updated June 2018. Available online: http://www.who.int/csr/disease/coronavirus_infections/mers-investigationcases/en/ (accessed on 30 July 2018).
48. WHO. WHO Guidance: MERS-CoV Intitial Interview Questionnaire of Cases, Updated 24 May 2017. Available online: http://www.who.int/csr/disease/coronavirus_infections/MERS_case_investigation_questionnaire.pdf?ua=1 (accessed on 30 July 2018).