-
1
-
-
85037364376
-
Recent and future directions in immunotherapy of cutaneous melanoma
-
Sadozai H, Gruber T, Hunger RE, et al. Recent and future directions in immunotherapy of cutaneous melanoma. Front Immunol. 2017;8:1617
-
(2017)
Front Immunol
, vol.8
, pp. 1617
-
-
Sadozai, H.1
Gruber, T.2
Hunger, R.E.3
-
2
-
-
84896714827
-
Safety and efficacy of vemurafenib in BRAF (V600E) and BRAF (V600F) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomized, open-label study
-
Mar
-
McArthur GA, Chapman PB, Robert C, et al. Safety and efficacy of vemurafenib in BRAF (V600E) and BRAF (V600F) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomized, open-label study. Lancet Oncol. 2014 Mar;15(3):323–332
-
(2014)
Lancet Oncol
, vol.15
, Issue.3
, pp. 323-332
-
-
McArthur, G.A.1
Chapman, P.B.2
Robert, C.3
-
3
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open- label, phase 3 randomised controlled trial
-
Jul
-
Hauschild A, Grob JJ, Demidov LV, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open- label, phase 3 randomised controlled trial. Lancet. 2012 Jul 28;380(9839):358–365
-
(2012)
Lancet
, vol.380
, Issue.9839
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
-
4
-
-
84938739283
-
Dabrafenib and trametinib versus dabrafenib and placebo for val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
-
Aug
-
Long GV, Stroyakovsky DL, Gogas H, et al. Dabrafenib and trametinib versus dabrafenib and placebo for val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial. Lancet. 2015 Aug 1;386(9992):444–451
-
(2015)
Lancet
, vol.386
, Issue.9992
, pp. 444-451
-
-
Long, G.V.1
Stroyakovsky, D.L.2
Gogas, H.3
-
5
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Sep
-
Hodi FS, O’Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010 Sep 23;363(13):1290
-
(2010)
N Engl J Med
, vol.363
, Issue.13
, pp. 1290
-
-
-
6
-
-
34548240159
-
Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer
-
Jul
-
Ribas A, Hanson DC, Noe DA, et al. Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer. Oncologist. 2007 Jul;12(7):873–883
-
(2007)
Oncologist
, vol.12
, Issue.7
, pp. 873-883
-
-
Ribas, A.1
Hanson, D.C.2
Noe, D.A.3
-
7
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4-treatment (checkmate 037): a randomised, controlled, open-label, phase 3 trial
-
Apr
-
Weber JS, D’Angelo SP, Minor D, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4-treatment (checkmate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 2015 Apr;16(4):375–384
-
(2015)
Lancet Oncol
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D’Angelo, S.P.2
Minor, D.3
-
8
-
-
84929481481
-
Pembrolizumab versus ipilimumab in advanced melanoma
-
Jun
-
Robert C, Schachter J, Long GV, et al. Pembrolizumab versus ipilimumab in advanced melanoma. N Engl J Med. 2015 Jun;372(26):2521–2532
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
-
9
-
-
85030460514
-
Overall survival with combined nivolumab and ipilimumab in advanced melanoma
-
Oct
-
Wolchok JD, Chiarion-Sileni V, Gonzalez R, et al. Overall survival with combined nivolumab and ipilimumab in advanced melanoma. N Engl J Med. 2017 Oct 5;377(14):1345–1356
-
(2017)
N Engl J Med
, vol.377
, Issue.14
, pp. 1345-1356
-
-
Wolchok, J.D.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
10
-
-
85007598523
-
Durable, long-term survival in previously treated patients with advanced melanoma (MEL) who received nivolumab (NIVO) monotherapy in a phase I trial
-
Jul
-
Hodi FS, Kluger H, Sznol M, et al. Durable, long-term survival in previously treated patients with advanced melanoma (MEL) who received nivolumab (NIVO) monotherapy in a phase I trial. Cancer Res. 2016 Jul;76(14 Suppl):abstr CT001
-
(2016)
Cancer Res
, vol.76
, Issue.14
, pp. CT001
-
-
Hodi, F.S.1
Kluger, H.2
Sznol, M.3
-
11
-
-
84867370942
-
Thymosin α1 in melanoma: from the clinical trial setting to the daily practice and beyond
-
Danielli R, Fonsatti E, Calabrò L, et al. Thymosin α1 in melanoma: from the clinical trial setting to the daily practice and beyond. Ann N Y Acad Sci. 2012;1270:8–12
-
(2012)
Ann N Y Acad Sci
, vol.1270
, pp. 8-12
-
-
Danielli, R.1
Fonsatti, E.2
Calabrò, L.3
-
12
-
-
0025696176
-
Combination treatment using thymosin alpha one and interferon after cyclophosphamide is able to cure lewis lung carcinoma in mice
-
Garaci E, Mastino A, Pica F, et al. Combination treatment using thymosin alpha one and interferon after cyclophosphamide is able to cure lewis lung carcinoma in mice. Cancer Immunol Immunother. 1990;32(3):154–160
-
(1990)
Cancer Immunol Immunother
, vol.32
, Issue.3
, pp. 154-160
-
-
Garaci, E.1
Mastino, A.2
Pica, F.3
-
13
-
-
0028287389
-
Anti-tumor effect of combined treatment with thymosin alpha 1 and interleukin-2 after 5-fluorouracil in liver metastases from colorectal cancer in rats
-
Jun
-
Rasi G, Silecchia G, Sinibaldi-Vallebona P, et al. Anti-tumor effect of combined treatment with thymosin alpha 1 and interleukin-2 after 5-fluorouracil in liver metastases from colorectal cancer in rats. Int J Cancer. 1994 Jun 1;57(5):701–705
-
(1994)
Int J Cancer
, vol.57
, Issue.5
, pp. 701-705
-
-
Rasi, G.1
Silecchia, G.2
Sinibaldi-Vallebona, P.3
-
14
-
-
0033621845
-
Thymosin alpha 1 regulates MHC expression in FRTL-5 cells at trascriptional level
-
Mar
-
Giuliani C, Napolitano G, Mastino A, et al. Thymosin alpha 1 regulates MHC expression in FRTL-5 cells at trascriptional level. Eur JImmunol. 2000 Mar;30(3):778–786
-
(2000)
Eur JImmunol
, vol.30
, Issue.3
, pp. 778-786
-
-
Giuliani, C.1
Napolitano, G.2
Mastino, A.3
-
15
-
-
0037905334
-
Thymalfasin up-regulates tumor antigen expression in colorectal cancer cells
-
Sinibaldi Vallebona P, Pierimarchi P, Moroni G, et al. Thymalfasin up-regulates tumor antigen expression in colorectal cancer cells. Tumor Biol. 2002;23:45
-
(2002)
Tumor Biol
, vol.23-45
-
-
Sinibaldi Vallebona, P.1
Pierimarchi, P.2
Moroni, G.3
-
16
-
-
77950469665
-
Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma
-
Apr
-
Maio M, Mackiewicz A, Testori A, et al. Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma. J Clin Oncol. 2010 Apr;28(10):1780–1787
-
(2010)
J Clin Oncol
, vol.28
, Issue.10
, pp. 1780-1787
-
-
Maio, M.1
Mackiewicz, A.2
Testori, A.3
-
17
-
-
67651249513
-
Effect of Ipilimumab treatment on 18-months survival: update of patients (pts) with advanced melanoma treated with 10mg/Kg ipilimumab in three phase II clinical trials
-
O’Day S, Weber J, Lebbe C, et al. Effect of Ipilimumab treatment on 18-months survival: update of patients (pts) with advanced melanoma treated with 10mg/Kg ipilimumab in three phase II clinical trials. J Clin Oncol. 2009;27(15 suppl):9033
-
(2009)
J Clin Oncol
, vol.27
, Issue.15
, pp. 9033
-
-
-
18
-
-
84886119112
-
Clinical experience with ipilimumab 10 mg/Kg in patients with melanoma treated at Italian centres as part of a european expanded access programme
-
Oct
-
Altomonte M, Di Giacomo A, Queirolo P, et al. Clinical experience with ipilimumab 10 mg/Kg in patients with melanoma treated at Italian centres as part of a european expanded access programme. J Exp Clin Cancer Res. 2013 Oct 25;32:82
-
(2013)
J Exp Clin Cancer Res
, vol.32
, pp. 82
-
-
Altomonte, M.1
Di Giacomo, A.2
Queirolo, P.3
-
19
-
-
84901246811
-
Clinical experience with ipilimumab 3 mg/Kg: real-world efficacy and safety data from an expanded access programme cohort
-
May
-
Ascierto PA, Simeone E, Sileni VC, et al. Clinical experience with ipilimumab 3 mg/Kg: real-world efficacy and safety data from an expanded access programme cohort. J Transl Med. 2014 May 7;12:116
-
(2014)
J Transl Med
, vol.12
, pp. 116
-
-
Ascierto, P.A.1
Simeone, E.2
Sileni, V.C.3
-
20
-
-
79959772576
-
Ipilimumab plus dacarbazine for previiously untreated metastatic melanoma
-
June
-
Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previiously untreated metastatic melanoma. N Engl J Med. 2011 June 30;364(26):2517–2526
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
21
-
-
84928917822
-
Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma
-
Jun
-
Schadendorf D, Hodi FS, Robert C, et al. Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma. J Clin Oncol. 2015 Jun 10;33(17):1889–1894
-
(2015)
J Clin Oncol
, vol.33
, Issue.17
, pp. 1889-1894
-
-
Schadendorf, D.1
Hodi, F.S.2
Robert, C.3
-
22
-
-
84878875962
-
Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10 mg/Kg within an expanded access programme
-
Jun
-
Di Giacomo AM, Calabrò L, Danielli R, et al. Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10 mg/Kg within an expanded access programme. Cancer Immunol Immunother. 2013 Jun;62(6):1021–1028
-
(2013)
Cancer Immunol Immunother
, vol.62
, Issue.6
, pp. 1021-1028
-
-
Di Giacomo, A.M.1
Calabrò, L.2
Danielli, R.3
-
23
-
-
84930872031
-
Baseline neutrophil-to-lymphocyte ratio is associated with outcome of ipilimumab-treated metastatic melanoma patients
-
Jun
-
Ferrucci PF, Gandini S, Battaglia A, et al. Baseline neutrophil-to-lymphocyte ratio is associated with outcome of ipilimumab-treated metastatic melanoma patients. Br J Cancer. 2015 Jun;112(12):1904–1910
-
(2015)
Br J Cancer
, vol.112
, Issue.12
, pp. 1904-1910
-
-
Ferrucci, P.F.1
Gandini, S.2
Battaglia, A.3
-
24
-
-
85030472711
-
Baseline relative eosinophil count as a predictive biomarker for ipilimumab treatment in advanced melanoma
-
Aug
-
Ferrucci PF, Gandini S, Cocorocchio E, et al. Baseline relative eosinophil count as a predictive biomarker for ipilimumab treatment in advanced melanoma. Oncotarget. 2017 Aug 1;8(45):79809–79815
-
(2017)
Oncotarget
, vol.8
, Issue.45
, pp. 79809-79815
-
-
Ferrucci, P.F.1
Gandini, S.2
Cocorocchio, E.3
-
25
-
-
85016813132
-
Ipilimumab 10 mg/Kg versus ipilimumab 3mg/Kg in patients with unresectable or metastatic melanoma: a randomized, double blind, multicentre, phase 3 trial
-
Apr
-
Ascierto PA, Del Vecchio M, Robert C, et al. Ipilimumab 10 mg/Kg versus ipilimumab 3mg/Kg in patients with unresectable or metastatic melanoma: a randomized, double blind, multicentre, phase 3 trial. Lancet Oncol. 2017 Apr;18(5):611–622
-
(2017)
Lancet Oncol
, vol.18
, Issue.5
, pp. 611-622
-
-
Ascierto, P.A.1
Del Vecchio, M.2
Robert, C.3
|