Patterns of response to crizotinib in recurrent glioblastoma according to ALK and MET molecular profile in two patients

CNS oncology

Volumn 4, Issue 6, 2015, Pages 381-386

  Le Rhun, Emilie ^a   Chamberlain, Marc C ^b   Zairi, Fahed ^a   Delmaire, Christine ^a   Idbaih, Ahmed ^a   Renaud, Florence ^a,b   Maurage, Claude A lain ^a   Grégoire, Valérie ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

ALK; crizotinib; glioblastoma; MET; MET amplification; targeted therapy

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ANTINEOPLASTIC AGENT; CRIZOTINIB; DNA LIGASE; DNA METHYLTRANSFERASE; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE; MET PROTEIN, HUMAN; MGMT PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; SCATTER FACTOR RECEPTOR; TUMOR SUPPRESSOR PROTEIN;

ADULT; BRAIN; BRAIN NEOPLASMS; CASE REPORT; DRUG EFFECTS; FEMALE; FOLLOW UP; GENETICS; GLIOBLASTOMA; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY;

ADULT; ANTINEOPLASTIC AGENTS; BRAIN; BRAIN NEOPLASMS; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; FOLLOW-UP STUDIES; GLIOBLASTOMA; HUMANS; IMMUNOHISTOCHEMISTRY; ISOCITRATE DEHYDROGENASE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-MET; PYRAZOLES; PYRIDINES; RECEPTOR PROTEIN-TYROSINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 85050577857     PISSN: None     EISSN: 20450915     Source Type: Journal    
DOI: 10.2217/cns.15.30     Document Type: Article

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