Correlation of clinical illness with viremia in Zika virus disease during an outbreak in Singapore

BMC Infectious Diseases

Volumn 18, Issue 1, 2018, Pages

  Ng, Deborah H L ^a   Ho, Hanley J ^b   Chow, Angela ^b,c,d   Wong, Joshua ^b   Kyaw, Win Mar ^b   Tan, Adriana ^b   Chia, Po Ying ^a   Choy, Chiaw Yee ^a   Tan, Glorijoy ^a   Yeo, Tsin Wen ^a,d   Leo, Yee Sin ^a,c,d  

^a NATIONAL CENTRE FOR INFECTIOUS DISEASES   (Singapore)

^b TAN TOCK SENG HOSPITAL   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Outbreak; Singapore; Viremia; Zika

Indexed keywords

ABDOMINAL PAIN; ADULT; ARTHRALGIA; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; CONJUNCTIVITIS; CONTROLLED STUDY; CRACKLE; DIARRHEA; DISEASE ASSOCIATION; DISEASE DURATION; DISORIENTATION; EPIDEMIC; FEMALE; FEVER; HEADACHE; HOSPITAL ADMISSION; HUMAN; HYPOKALEMIA; JAUNDICE; LEUKOPENIA; LONGITUDINAL STUDY; LYMPHADENOPATHY; MALE; MYALGIA; NAUSEA AND VOMITING; PHARYNGITIS; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; RASH; SINGAPORE; THROMBOCYTOPENIA; VIREMIA; WHEEZING; ZIKA FEVER; BLOOD; EPIDEMIOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; VIROLOGY; ZIKA VIRUS;

ADULT; COHORT STUDIES; DISEASE OUTBREAKS; EXANTHEMA; FEMALE; FEVER; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; SINGAPORE; VIREMIA; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85049534799     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-018-3211-9     Document Type: Article

References (12)

1. World Health Organisation. WHO Director-General summarizes the outcome of the Emergency Committee regarding clusters of microcephaly and Guillain-Barré syndrome. http://www.who.int/mediacentre/news/statements/2016/emergency-committee-zika-microcephaly/en/. Accessed 14th Sept 2016.
2. Musso D, Gubler DJ. Zika virus. Clin Microbiol Rev. 2016;29:487-524.
3. Leo Y, Chow A. Zika virus has arrived in Singapore. Lancet Inf Dis. 2016;16(12):1317-9.
4. The Singapore Zika Study Group. Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis. Lancet Inf Dis. 2017;17(8):813-21.
5. Duffy MR, Chen T-H, Hancock WT, Powers AM, Kool JL, Lanciotti RS, et al. Zika virus outbreak on Yap Island, Federated States of Micronesia. N Engl J Med. 2009;360:2536-43.
6. Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, et al. Genetic and serologic properties of Zika virus associated with an epidemic, yap state, Micronesia, 2007. Emerg Inf Dis. 2008;14(8):1232-9. https://doi.org/10.3201/eid1408.080287.
7. Cerbino-Neto J, Mesquita EC, Souza TM, Parreira V, Wittlin BB, Durovni B, et al. Clinical manifestations of Zika virus infection, Rio de Janeiro, Brazil. 2015 Emerg Infect Dis. 2016;22(7):1318-20. https://doi.org/10.3201/eid2207.160375
8. Vaughn DW, Green S, Kalayanarooj S, Innis BL, Nimmanitya S, Suntayakorn S, et al. Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis. 1997;176:322-30.
9. D'Ortenzio E, Matheron S, Yazdanpanah Y, de Lamballerie X, Hubert B, Piorkowski G, et al. Evidence of sexual transmission of Zika virus. N Engl J Med. 2016;374(22):2195-8.
10. Plourde AR, Bloch EM. A literature review of Zika virus. Emerg Infect Dis. 2016;22(7):1185-92.
11. Lizarraga KJ, Nayer A. Dengue-associated kidney disease. J Nephropathol. 2014;3(2):57-62. https://doi.org/10.12860/jnp.2014.13. Epub 2013 Dec 28
12. Alcendor DJ. Zika virus infection of the human glomerular cells: implications for viral reservoirs and renal pathogenesis. J Infect Dis. 2017;216(2):162-71. https://doi.org/10.1093/infdis/jix171.