The inflammasome potentiates influenza/Staphylococcus aureus superinfection in mice

JCI insight

Volumn 3, Issue 7, 2018, Pages

  Robinson, Keven M ^a   Ramanan, Krishnaveni ^a   Clay, Michelle E ^b   McHugh, Kevin J ^c   Pilewski, Matthew J ^a   Nickolich, Kara L ^a   Corey, Catherine ^a,d   Shiva, Sruti ^a,d   Wang, Jieru ^c   Muzumdar, Radhika ^c   Alcorn, John F ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d Department of Pharmacology and Chemical Biology ^*

Author keywords

Bacterial infections; Immunology; Influenza; Pulmonology

Indexed keywords

CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; FURAN DERIVATIVE; IL1B PROTEIN, MOUSE; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MCC950; PYCARD PROTEIN, MOUSE; SULFONAMIDE;

ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECT; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA; KNOCKOUT MOUSE; LUNG; MALE; METABOLISM; MICROBIOLOGY; MORTALITY; MOUSE; PATHOLOGY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SUPERINFECTION; VIROLOGY;

ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; DISEASE MODELS, ANIMAL; FURANS; HUMANS; INFLAMMASOMES; INFLUENZA, HUMAN; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, INTERLEUKIN-1; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SULFONAMIDES; SUPERINFECTION;

EID: 85048930815     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.97470     Document Type: Article

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