Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing T reg cells through modification of the intestinal microbiota

Nature Immunology

Volumn 19, Issue 7, 2018, Pages 755-765

  Tang, Ce ^a,b   Kakuta, Shigeru ^b,c   Shimizu, Kenji ^a,b,d   Kadoki, Motohiko ^a,b,e   Kamiya, Tomonori ^a,b,f   Shimazu, Tomoyuki ^a,g   Kubo, Sachiko ^a,b   Saijo, Shinobu ^b,h   Ishigame, Harumichi ^b,i   Nakae, Susumu ^b   Iwakura, Yoichiro ^a,b  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g MIYAGI UNIVERSITY   (Japan)

^h CHIBA UNIVERSITY   (Japan)

ⁱ Institute of Physical and Chemical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 17F; ANG4 PROTEIN, MOUSE; BETA DEFENSIN; PANCREATIC RIBONUCLEASE; PHOSPHOLIPASE A2;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLOSTRIDIUM; COLITIS; COLON CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; INTESTINE FLORA; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INTESTINE; ISOLATION AND PURIFICATION; KNOCKOUT MOUSE; PHYSIOLOGY; PREVOTELLA;

ANIMALS; BETA-DEFENSINS; CELLS, CULTURED; CLOSTRIDIUM; COLITIS; GASTROINTESTINAL MICROBIOME; INTERLEUKIN-17; INTESTINES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOLIPASES A2; PREVOTELLA; RIBONUCLEASE, PANCREATIC; T-LYMPHOCYTES, REGULATORY;

EID: 85048696117     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/s41590-018-0134-y     Document Type: Article

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