Mpl and the hematopoietic stem cell

Leukemia

Volumn 16, Issue 4, 2002, Pages 738-739

  Kaushansky, K ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CYTOKINES; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, CYTOKINE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, THROMBOPOIETIN; THROMBOCYTOPENIA; THROMBOPOIETIN;

PADGEM PROTEIN; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD TRANSFUSION; BONE MARROW CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL FEATURE; CONGENITAL AMEGAKARYOCYTIC THROMBOCYTOPENIA; DISEASE COURSE; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENE THERAPY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; THROMBOCYTOPENIA;

EID: 85047696981     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402398     Document Type: Article

References (5)

1. The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells
2. Role of c-Mpl in early hematopoiesis
3. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl
4. c-Mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia
5. Defective response to thrombopoietin and impaired expression of c-Mpl mRNA of bone marrow cells in congenital amegakaryocytic thrombocytopenia