Age-dependent decrease of polymeric Ig receptor expression and IgA elevation in ddY mice: A possible cause of IgA nephropathy

Laboratory Investigation

Volumn 84, Issue 1, 2004, Pages 63-70

  Yanagihara, Takeshi ^a   Kumagai, Yoshihiro ^a   Norose, Yoshihiko ^a   Moro, Itaru ^b   Nanno, Masanobu ^c   Murakami, Mutsumi ^a   Takahashi, Hidemi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

ddY mice; IgA nephropathy; Mucosal immunity; plgR; RT PCR

Indexed keywords

IMMUNOGLOBULIN A; SECRETORY COMPONENT; MESSENGER RNA;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLEARANCE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; KIDNEY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; TRANSCYTOSIS; AGING; ANIMAL; BAGG ALBINO MOUSE; COMPARATIVE STUDY; DIMERIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; GERMFREE ANIMAL; IMMUNOLOGY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY CORTEX; METABOLISM; PATHOLOGY; PHYSIOLOGY; SPECIES DIFFERENCE;

AGING; ANIMALS; DIMERIZATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION; GLOMERULONEPHRITIS, IGA; IMMUNOGLOBULIN A; INJECTIONS, INTRAVENOUS; INTESTINE, SMALL; KIDNEY CORTEX; MICE; MICE, INBRED BALB C; RECEPTORS, POLYMERIC IMMUNOGLOBULIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIES SPECIFICITY; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 85047692821     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700012     Document Type: Article

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