Caveolin-1 immmunohistochemical analysis in differentiating chromophobe renal cell carcinoma from renal oncocytoma

American Journal of Clinical Pathology

Volumn 125, Issue 3, 2006, Pages 392-398

  Garcia, Ediberto ^a   Li, Maomi ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Caveolin 1; Chromophobe renal cell carcinoma; Cytokeratin 7; Kidney; Oncocytoma

Indexed keywords

CAVEOLIN 1; CYTOKERATIN 7; KERATIN; KRT7 PROTEIN, HUMAN; TUMOR MARKER;

ARTICLE; BLOOD VESSEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CAPSULE; KIDNEY CARCINOMA; KIDNEY CORTEX; KIDNEY TUBULE EPITHELIUM; ONCOCYTOMA; PRIORITY JOURNAL; CELL COUNT; CHEMISTRY; KIDNEY; KIDNEY TUMOR; PATHOLOGY;

ADENOMA, OXYPHILIC; CARCINOMA, RENAL CELL; CAVEOLIN 1; CELL COUNT; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; KERATIN-7; KERATINS; KIDNEY; KIDNEY NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 85047691003     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AMDENQCHTMNFC7U3     Document Type: Article

References (22)

1. Murphy WM, Grignon DJ, Perlman EJ. Tumors of the Kidney, Bladder, and Related Urinary Structures. Washington, DC: Armed Forces Institute of Pathology; 2004:101-174. Atlas of Tumor Pathology; Fourth Series, Fascicle 1.
2. Tickoo SK, Amin MB, Zarbo RJ. Colloidal iron staining in renal epithelial neoplasms, including chromophobe renal cell carcinoma. Am J Surg Pathol. 1998;22:419-424.
3. Leroy X, Moukassa D, Copin MC, et al. Utility of cytokeratin 7 for distinguishing chromophobe renal cell carcinoma from renal oncocytoma. Eur Urol. 2000;37:484-487.
4. Mathers ME, Pollock AM, March C, et al. Cytokeratin 7: a useful adjunct in the diagnosis of chromophobe renal cell carcinoma. Histopathology. 2002;40:563-567.
5. Wu SL, Kothari P, Wheeler TM, et al. Cytokeratin 7 and 20 immunoreactivity in chromophobe renal cell carcinomas and renal oncocytomas. Mod Pathol. 2002;15:712-717.
6. Abrahams NA, MacLennan GT, Khoury JD, et al. Chromophobe renal cell carcinoma: a comparative study of histological, immunohistochemical and ultrastructural features using high throughput tissue microarray. Hstopathology. 2004;45;593-602.
7. Cohen AW, Hnasko R, Schubert W, et al. Role of caveolae and caveolins in health and disease. Physiol Rev. 2004;84:1341-1379.
8. Yang G, Truong LD, Timme TL, et al. Elevated expression of caveolin is associated with prostate and breast cancer. Clin Cancer Res. 1998;4:1873-1880.
9. Kato K, Hida Y, Miyamoto M, et al. Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Cancer. 2002;94:929-933.
10. Fine SW, Lisanti MP, Galbiati F, et al. Elevated expression of caveolin-1 in adenocarcinoma of the colon. Am J Clin Pathol. 2001;115:719-724.
11. Rajjayabun PH, Garg S, Durkan GC, et al. Caveolin-1 expression is associated with high grade bladder cancer. Urology. 2001;58:811-814.
12. Fong A, Garcia, E, Gwynn L, et al. Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation. Am J Clin Pathol 2003;120:93-100.
13. Langner C, Wegscheider BJ, Ratschek M, et al. Keratin immunohistochemistry in renal cell carcinoma subtypes and renal oncocytomas: a systemic analysis of 233 tumors. Virchows Arch. 2004;444:127-134.
14. Chu P, Weiss LM. Cytokeratin 14 immunoreactivity distinguishes oncocytic tumor from its renal mimics: an immunohistochemical study of 63 cases. Histopathology. 2001;39:455-462.
15. Mazal PR, Exner M, Haitel A, et al. Expression of kidney-specific cadherin distinguishes chromophobe renal cell carcinoma from renal oncocytoma. Hum Pathol. 2005;36:22-28.
16. Shen SS, Krishna B, Chirala R, et al. Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms. Mod Pathol. 2005;18:933-940.
17. Pan CC, Chen PCH, Ho DMT. The diagnostic utility of MOC31, BerEP4, RCC marker and CD10 in the classification of renal cell carcinoma and renal oncocytoma: an immunohistochemical analysis of 328 cases. Histopathology. 2004;45:452-459.
18. Avery AK, Beekstead J, Renshaw AA, et al. Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms. Am J Surg Pathol. 2000;24:203-210.
19. Pan CC, Chen PC, Chiang H. Overexpression of KIT (CD117) in chromophobe renal cell carcinoma and renal oncocytoma. Am J Clin Pathol. 2004;121:878-883.
20. Patton KT, Tretiakova MS, Yao JL, et al. Expression of RON proto-oncogene in renal oncocytoma and chromophobe renal cell carcinoma. Am J Surg Pathol. 2004;28:1045-1050.
21. Campbell L, Gumbleton M, Griffiths DFR. Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma. Br J Cancer. 2003;89:1909-1913.
22. Carrion R, Morgan BE, Tannenbaum M, et al. Caveolin expression in adult renal tumors. Urol Oncol. 2003;21:191-196.