Minireview: Inhibin binding protein (InhBP/p120), betaglycan, and the continuing search for the inhibin receptor

Molecular Endocrinology

Volumn 16, Issue 2, 2002, Pages 207-212

  Bernard, Daniel J ^a,c   Chapman, Stacey C ^a   Woodruff, Teresa K ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c POPULATION COUNCIL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; GLYCAN DERIVATIVE; INHIBIN; INHIBIN RECEPTOR; PROTEIN P120; RECEPTOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG; ACTIVIN; ACTIVIN RECEPTOR; BETAGLYCAN; PROTEOGLYCAN; RECEPTOR;

ANIMAL CELL; HYPOPHYSIS GONAD SYSTEM; LEYDIG CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; RECEPTOR BINDING; SHORT SURVEY; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; ENZYME SPECIFICITY; FEMALE; HUMAN; HYPOPHYSIS; MALE; METABOLISM; OVARY; REVIEW;

ANIMALIA;

ACTIVIN RECEPTORS; ACTIVINS; ANIMALS; FEMALE; HUMANS; LEYDIG CELLS; MALE; OVARY; PITUITARY GLAND; PROTEOGLYCANS; RECEPTORS, PEPTIDE; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY;

EID: 85047683466     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.16.2.0783     Document Type: Short Survey

References (41)

1. The transcriptional co-activator P/CAF potentiates TGF-β/Smad signaling
2. Transcriptional control by the TGF-β/Smad signaling system
3. Activin signal transduction pathways
4. Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP
5. Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro
6. Hope, hypothesis, and the inhibin receptor. Does specific inhibin binding suggest there is a specific inhibin receptor?
7. Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
8. Activin and inhibin have antagonistic effects on ligand-dependent heteromerization of the type I and type II activin receptors and human erythroid differentiation
9. Expression cloning of an activin receptor, a predicted transmembrane serine kinase
10. Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells
11. Inhibin antagonizes inhibition of liver cell growth by activin by a dominant-negative mechanism
12. Inhibins, activins, and follistatins: Gonadal proteins modulating the secretion of follicle-stimulating hormone
13. Inhibin, activin, and follistatin: Regulation of follicle-stimulating hormone messenger ribonucleic acid levels
14. Effect of recombinant activin-A on gonadotropin secretion in the female rat
15. Perifusion of rat pituitary cells with gonadotropin-releasing hormone, activin, and inhibin reveals distinct effects on gonadotropin gene expression and secretion
16. Activin-A inhibits proopiomelanocortin messenger RNA accumulation and adrenocorticotropin secretion of AtT20 cells
17. 125I]inhibin-A to the adult rat ovary
18. Localization of inhibin and activin binding sites in the testis during development by in situ ligand binding
19. Identification of an inhibin receptor in gonadal tumors from inhibin α-subunit knock-out mice
20. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
21. Structure and expression of a membrane component of the inhibin receptor system
22. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system
23. Expression cloning and characterization of the TGF-β type III receptor
24. Betaglycan presents ligand to the TGF β signaling receptor
25. Expression of transforming growth factor type III receptor in vascular endothelial cells increases their responsiveness to transforming growth factor β 2
26. Type III TGF-β receptor-independent signalling of TGF-β2 via TβRII-B, an alternatively spliced TGF-β type II receptor
27. Inhibin binding protein in rats: Alternative transcripts and regulation in the pituitary across the estrous cycle
28. Antagonism of activin by inhibin and inhibin receptors: A functional role for betaglycan
29. Identification of high affinity binding sites for inhibin on ovine pituitary cells in culture
30. Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells
31. Production and actions of inhibin and activin during folliculogenesis in the rat
32. Identification of specific inhibin A-binding proteins on mouse Leydig (TM3) and sertoli (TM4) cell lines
33. Ligand binding and functional properties of betaglycan, a co-receptor of the transforming growth factor-β superfamily. Specialized binding regions for transforming growth factor-β and inhibin A
34. Modulation of activin signal transduction by inhibin B and inhibin-binding protein (InhBP)
35. Is the action of inhibin mediated via a unique receptor?
36. Characterization of activin A binding sites on the human leukemia cell line K562
37. Identification of a specific receptor for erythroid differentiation factor on follicular granulosa cell
38. GDNF family neurotrophic factor signaling: Four masters, one servant?
39. GDNF recruits the signaling crew into lipid rafts
40. Functional roles for the cytoplasmic domain of the type III transforming growth factor β receptor in regulating transforming growth factor β signaling
41. Requirement of type III TGF-β receptor for endocardial cell transformation in the heart