A single residue (Arg46) located within the N-terminus of the V1a vasopressin receptor is critical for binding vasopressin but not peptide or nonpeptide antagonists

Molecular Endocrinology

Volumn 16, Issue 3, 2002, Pages 600-609

  Hawtin, Stuart R ^a   Wesley, Victoria J ^a   Parslow, Rosemary A ^a   Simms, John ^a   Miles, Alice ^a   McEwan, Kim ^a   Wheatley, Mark ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (BETA MERCAPTO BETA,BETA CYCLOPENTAMETHYLENEPROPIONIC ACID); ALANINE; ARGININE; EPITOPE; G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; GLYCINE; LEUCINE; LYSINE; NEUROHYPOPHYSIS HORMONE; PEPTIDE; PROPIONIC ACID DERIVATIVE; RELCOVAPTAN; UNCLASSIFIED DRUG; VASOPRESSIN; VASOPRESSIN ANTAGONIST; VASOPRESSIN DERIVATIVE; VASOPRESSIN V1 RECEPTOR; VASOPRESSIN V1A RECEPTOR; ARGIPRESSIN; TRITIUM; VASOPRESSIN RECEPTOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL COMMUNICATION; CONTROLLED STUDY; EMBRYO; GENETIC CONSERVATION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; RADIOASSAY; SECOND MESSENGER; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; RAT; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; ARGININE VASOPRESSIN; BINDING SITES; CELL LINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; RADIOLIGAND ASSAY; RATS; RECEPTORS, VASOPRESSIN; SECOND MESSENGER SYSTEMS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRITIUM; VASOPRESSINS;

EID: 85047682821     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.16.3.0795     Document Type: Article

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