Editorial: Targeted gene disruption in endocrine research - The case of glucagon-like peptide-1 and neuroendocrine function

Endocrinology

Volumn 141, Issue 2, 2000, Pages 473-475

  Seeley, R J ^a   Woods, S C ^a   D'Alessio, D ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; ESTRADIOL; GLUCAGON LIKE PEPTIDE 1; INSULIN; LUTEINIZING HORMONE; PREPROGLUCAGON; PROGESTERONE; TESTOSTERONE; THYROXINE; GLUCAGON; GLUCAGON LIKE PEPTIDE RECEPTOR; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE RECEPTOR; PEPTIDE FRAGMENT; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; CONTROLLED STUDY; EDITORIAL; FOOD INTAKE; GENE DISRUPTION; GENE TARGETING; GENETIC MANIPULATION; GLUCOSE HOMEOSTASIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INSULIN RELEASE; KNOCKOUT MOUSE; MOLECULAR CLONING; MOUSE; NEUROENDOCRINOLOGY; NEUROTRANSMISSION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REPRODUCTION; THALAMUS MIDLINE NUCLEUS; ANIMAL; GENE DELETION; GENETICS; MOUSE MUTANT; NEUROSECRETION; NOTE; PHYSIOLOGY;

ANIMALS; GENE DELETION; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; MICE; MICE, KNOCKOUT; NEUROSECRETORY SYSTEMS; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; RECEPTORS, GLUCAGON;

EID: 85047681645     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.2.7372     Document Type: Editorial

References (21)

1. Neuroendocrine function in mice with complete disruption of glucagon-like peptide-1 receptor signaling
2. Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem
3. Hamster preproglucagon contains the sequence of glucagon and two related peptides
4. Glucagon-like peptide-1 7-36: A physiological incretin in man
5. Tissue-specific expression of the human receptor for glucagon-like peptide 1: Brain, heart and pancreatic forms have the same deduced amino acid sequences
6. Expression cloning of the pancreatic b-cell receptor for the gluco-incretin hormone glucagon-like peptide 1
7. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
8. Glucagon-like peptide-1 is a physiological incretin in rat
9. Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide
10. Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons
11. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
12. A role for glucagon-like peptide-1 in the central regulation of feeding
13. Central administration of GLP-1-(7-36) amide inhibits food and water retake in rats
14. Glucagon-like peptide-1 and satiety?
15. Central infusion of GLP-1-(7-36) amide receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem
16. Effects of aging and a high fat diet on body weight and glucose tolerance in glucagon-like peptide-1 -/- mice
17. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
18. Central administration of glucagon-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat
19. Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line
20. Glucagon-like peptide-1 (GLP-1) releases thyrotropin (TSH): Characterization of binding sites for GLP-1 on alpha-TSH cells
21. Life without neuropeptide Y