Responses of the rabbit epicardial coronary artery to acetylcholine and adrenoceptor agonists

Cardiovascular Research

Volumn 25, Issue 3, 1991, Pages 256-262

  Corr, Laura ^a,b   Burnstock, Geoffrey ^a,b   Poole Wilson, Philip ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Acetylcholine; Adrenoceptors; Coronary arteries; Endothelium; Rabbit; Smooth muscle

Indexed keywords

ACETYLCHOLINE; ISOPRENALINE; NORADRENALIN; PHENOXYBENZAMINE; PHENTOLAMINE; POTASSIUM CHLORIDE; PROPRANOLOL; SALBUTAMOL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASCULAR ENDOTHELIUM; VASODILATATION;

ACETYLCHOLINE; ADRENERGIC AGONISTS; ANIMAL; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; IN VITRO; MUSCLE, SMOOTH, VASCULAR; RABBITS; RECEPTORS, ADRENERGIC; SUPPORT, NON-U.S. GOV'T; VASOCONSTRICTION; VASODILATION;

EID: 85047680553     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1093/cvr/25.3.256     Document Type: Review

References (40)

1. Feigl EO. Coronary physiology. Physiol Rev 1983;63:1–205.
2. Young MA, Knight DR, Vatner SF. Autonomic control of large coronary arteries and resistance vessels. Prog Cardiovasc Dis 1987;30:211–34.
3. Furchgott RF, Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373–6.
4. De Mey JG, Vanhoutte PM. Role of the intima in cholinergic and purinergic relaxation of isolated canine femoral arteries. J Physiol (Lond) 1981;316:346–55.
5. Furchgott RM. The requirement for endothelial cells in the relaxation of arteries by acetylcholine and some other vasodilators. Trends Pharmacol Sci 1981;2:173–6.
6. Angus JA, Cocks TM. Role of endothelium in vascular responses to norepinephrine, serotonin and acetylcholine. Bibl Cardiol 1984;38:43–52.
7. Graser T, Leisner H, Tiedt N. Absence of role of endothelium in the response of isolated porcine coronary arteries to acetylcholine. Cardiovasc Res 1986;20:299–302.
8. Nagata Y, Araki H, Tomoike H, Nakamura M. Vasoconstrictor agents correlatively alter diameter and tension development in isolated pig coronary arteries. Basic Res Cardiol 1985;80:210–7.
9. Miller RC, Cornish EJ, Goldie RG. Responses of sheep and kitten isolated coronary arteries to some vasoactive agents. Pharmacol Res Commun 1984;16:667–77.
10. Kalsner S. The effects of periarterial nerve activation on coronary vessel tone in an isolated and perfused slab of beef ventricle. Can J Physiol Pharmacol 1979;57:291–7.
11. Wali FA. Effects of local anaesthetics on responses of human saphenous vein and bovine coronary artery to neurotransmitters, acetylcholine, noradrenaline and 5-hydroxytryptamine. Gen Pharmacol 1986;17:405–11.
12. de la Lande IS, Harvey JA, Holt S. Response of the rabbit coronary arteries to autonomic agents. Blood Vessels 1974;11:319–37.
13. Saeed M, Schmidli J, Metz M, Bing RJ. Perfused rabbit heart: endothelium-derived relaxing factor in coronary arteries. J Cardiovasc Pharmacol 1986;8:257–61.
14. Taira N, Satoh K, Maruyama M, Yamashita S. Sustained coronary constriction and its antagonism by calcium-blocking agents in monkeys and baboons. Circ Res 1983;52:40–6.
15. Toda N, Okamura T, Shimizu I, Tatsuno Y. Postmortem functional changes in coronary and cerebral arteries from humans and monkeys. Cardiovasc Res 1985;19:707–13.
16. Bossaller C, Habib GB, Tamamoto H, Williams C, Wells S, Henry PD. Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5′-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta. J Clin Invest 1987;79:170–4.
17. Forstermann U, Mugge A, Frolich JC. Endothelium-dependent relaxation of human epicardial coronary arteries: frequent lack of effect of acetylcholine. Eur J Pharmacol 1986;128:277–81.
18. Forstermann U, Mugge A, Alheid U, Haverich A, Frolich JC. Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries. Circ Res 1988;62:185–90.
19. Thom S, Hughes A, Martin G, Sever P. Endothelium-dependent relaxation in isolated human arteries and veins. Clin Sci 1987;73:547–52.
20. Ross G. Adrenergic responses of the coronary vessels. Circ Res 1976;39:461–5.
21. Rubanyi G, Vanhoutte PM. Endothelium-removal decreases relaxations of canine coronary arteries caused by beta-adrenergic agonists and adenosine. J Cardiovasc Pharmacol 1985;7:139–44.
22. Cohen RA, Zitnay KM, Weisbrod RM, Tesfamariam B. Influence of the endothelium on tone and the response of isolated pig coronary artery to norepinephrine. J Pharmacol Exp Ther 1988;244:550–5.
23. Cocks TM, Angus JA. Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin. Nature 1983;305:627–30.
24. Angus JA, Cocks TM, Satoh K. The alpha adrenoceptors on endothelial cells. Fed Proc 1986;45:2355–9.
25. Angus JA, Cocks TM, Satoh K. Alpha 2-adrenoceptors and endothelium-dependent relaxation in canine large arteries. Br J Pharmacol 1986;88:767–77.
26. Bevan JA, Osher JV. A direct method for recording tension changes in the wall of small blood vessels in vitro. Agents Actions 1972;2:257–60.
27. Nakayama K, Fleckenstein A, Byon YK, Fleckenstein-Grun G. Fundamental physiology of coronary vascular smooth musculature from extramural stem arteries of pigs and rabbits. Eur J Cardiol 1978;8:319–35.
28. Han C, Abel PW. Neuropeptide Y potentiates contraction and inhibits relaxation of rabbit coronary arteries. J Cardiovasc Pharmacol 1987;9:675–81.
29. Ann HS, Ku DD. Magnesium inhibits basal release of endothelium-derived relaxing factor in canine coronary arteries. Eur J Pharmacol 1986;130:353–5.
30. Sakai KJ. Coronary vasoconstriction by locally administered acetylcholine, carbachol and bethanecol in isolated, donor-perfused rat hearts. Br J Pharmacol 1980;68:625–32.
31. Van Winkle DM, Romson JL, Feigl EO. Cholinergic coronary vasodilation in dogs and baboons (abstract). FASEB J 1988;2:A495.
32. Kalsner S. Cholinergic mechanisms in human coronary artery preparations: implications of species differences. J Physiol (Lond) 1985;358:509–26.
33. Sakai K, Akima M, Shiraki Y, Hoshino E. Effects of a new anti-anginal agent, nicorandil, on the cardiovascular system of the miniature pig: with special reference to coronary vasospasm. J Pharmacol Exp Ther 1983;227:220–8.
34. Werns SW, Walton JA, Hsia HH, Nabel EG, Sanz ML, Pitt B. Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease. Circulation 1989;79:287–91.
35. Fish RD, Nabel EG, Selwyn AP, et al. Responses of coronary arteries of cardiac transplant patients to acetylcholine. J Clin Invest 1988;81:21–31.
36. Takaoka K, Yasue H, Horio Y. Possible role of coronary spasm in acute myocardial infarction precipitated by hyperventilation. Br Heart J 1988;59:256–8.
37. 2 subtypes by radioligand binding. Br J Pharmacol 1983;79:409–14.
38. Nakane T, Tsujimoto G, Hashimoto K, Chiba S. Beta adrenoceptors in the canine large coronary arteries: beta-1 adrenoceptors predominate in vasodilation. J Pharmacol Exp Ther 1988;245:936–43.
39. Macdonald PS, Dubbin PN, Dusting GJ. Beta-adrenoceptors on endothelial cells do not influence release of relaxing factor in dog coronary arteries. Clin Exp Pharmacol Physiol 1987;14:525–34.
40. White RE, Jolly SR, Carrier GO. Enhanced relaxation response of canine coronary artery to isoproterenol and salbutamol after removal of endothelial cells. Gen Pharmacol 1986;17:497–9.