Ischaemic preconditioning: From mechanisms to exploitation

Cardiovascular Research

Volumn 26, Issue 8, 1992, Pages 734-739

  Walker, David M ^a   Yellon, Derek M ^a  

^a UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Ischaemic preconditioning; Myocardial protection; Reperfusion

Indexed keywords

HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMAL; CORONARY DISEASE; DOGS; HUMAN; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION; MYOCARDIUM; SUPPORT, NON-U.S. GOV'T;

EID: 85047680234     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1093/cvr/26.8.734     Document Type: Article

References (80)

1. Maxwell MP, Hearse DJ, Yellon DM Species variation in the coronary collateral circulation during regional myocardial ischaemia: a critical determinant of the rate of evolution and extent of myocardial infarction. Cardiovasc Res 1987, 21: 737-46.
2. Schaper J, Schaper W Time course of myocardial necrosis. Cardiovasc Drugs Ther 1988, 2: 17-25.
3. Jennings RB, Hawkins UK, Lowe JK, Hill ML, Klotman S, Reimer KA Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog Am J Pathol 1978; 92:203-16.
4. Neely JR, Orotyohann LV. Role of glycolytic products in damage to the ischemic myocardium: dissociation of adenosine triphosphate levels and recovery of reperfused ischemic hearts Circ Res 1984, 55:816-24.
5. Reimer KA, Murry CE, Yamasawa I, Hill MI., Jennings RB Four brief periods of ischemia cause no cumulative ATP loss or necrosis Am J Physiol 1986 251(Heart Circ Physiol 20): H1306-15.
6. Geft IL, Fishbein MC, Ninomiya K, et al. Intermittent brief periods of ischemia have a cumulative effect and may cause myocardial necrosis. Circulation 1982:66:1150-3.
7. Murry CK, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium Circulation 1986, 74:1124-36
8. Murry CK, Richard VJ, Jennings RB, Reimer KA. Myocardial protection is lost before contractile function recovers from ischemic preconditioning Am J Physiol 1991 260(Heart Circ Physiol 29):H796-804.
9. Li GC, Vasquez BS, Gallagher KP, Lucchesi BR. Myocardial protection with preconditioning. Circulation 1990;82:609-19.
10. Cohen MV, Liu GS, Downey JM Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits Circulation 1991, 84:341-9.
11. Li Y, Kloner RA Cardioprotective effects of ischaemic "preconditioning" are not mediated by prostanoids. Cardiovasc Res 1992;26:226-31
12. Alkhulaifi AM, Browne E, Yellon DM. Ischaemic preconditioning limits infarct si/e in the rat heart (abstract). J Mol Cell Cardiol 1992;24(suppl I):S93.
13. Schon RJ, Rohmann S, Braun ER, Schaper W Ischemic preconditioning reduces infarct size in swine myocardium. Circ Res 1990.66:1133-42
14. Van Winkle DM, Thornton J, Downey JM. Cardioprotection from ischemic preconditioning is lost following prolonged reperfusion in rabbits (abstract). Circulation 1991;84(suppl II):432.
15. Schwarz ER, Mohn M, Sack S, Arras M. Duration of infarct size limiting effect of ischemic preconditioning in the pig (abstract) Circulation 1991, 84(suppl II):432
16. Nao BS, McClanahan TB, Groh MA. Schott RJ. Gallagher KP. The time limit of effective ischemic preconditioning in dogs (abstract). Circulation 1990;82(suppl III):271
17. Shiki K, Hearse DJ. Preconditioning of ischemic myocardium: reperfusion induced arrhythmias. Am J Physiol 1987;253(Heart Circ Physiol 22):H1470-6.
18. Hagar JM, Hale SL, Kloner RA. Effect of preconditioning ischemia on reperfusion arrhythmias after coronary artery occlusion and reperfusion in the rat. Circ Res 1991;68:61-8.
19. Osada M, Sato T, Komori S, Tamura K. Protective effect of preconditioning on reperfusion induced ventricular arrhythmias of isolated rat hearts. Cardiovasc Res 1991;25:441-4.
20. Vegh A, Szekeres L, Parratt JR. Protective effects of preconditioning of the ischaemic myocardium involve cyclo-oxygenase products. Cardiovasc Res 1990;24:1020-3.
21. Manning AS, Hearse DJ. Reperfusion induced arrhythmias: mechanisms and prevention. J Mol Cell Cardiol 1984;16: 497-518.
22. Barakat O, Van Wylen DGL, Mentzer RM, Lasley RD. Ischemic preconditioning improves postischemic recovery of function but shortens time to onset of ischemic contracture in isolated rat hearts (abstract). Circulation 1991;84(suppl II):433.
23. Vegh A, Szekeres L, Parratt JR. Transient ischaemia induced by rapid cardiac pacing results in myocardial preconditioning. Cardiovasc Res 1991;25:1051-3.
24. Marber MS, Walker DM, Yellon DM, Walker JM. Rapid atrial pacing fails to precondition the rabbit heart (abstract). J Mol Cell Cardiol 1992;24(suppl I):S92.
25. Shizukuda Y, Mallet RT, Lee S-C, Downey HF. Hypoxic preconditioning of ischaemic canine myocardium. Cardiovasc Res 1992;26:534-42.
26. Tani M, Asakura Y, Ebihara Y, Nakamura Y. Effect of preconditioning with anoxic perfusion on sarcoplasmic reticulum calcium uptake in reperfused rat hearts (abstract). Circulation 1991;84(suppl II):433.
27. Murry CE, Richard VJ, Reimer KA, Jennings RB. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ Res 1990;66:913-31.
28. Stahl LD, Weiss HR, Becker LC. Myocardial oxygen consumption, oxygen supply/demand heterogeneity and microvascular patency in regionally stunned myocardium. Circulation 1988;77:865-72.
29. Miura T, Goto M, Urabe K, Endoh A, Shimamoto K, Iimura O. Does myocardial stunning contribute to infarct size limitation by ischemic preconditioning? Circulation 1991;84:2504-12.
30. Jennings RB, Murry CE, Reimer KA. Energy metabolism in preconditioned and control myocardium: effect of total ischaemia. J Mol Cell Cardiol 1991;23:1449-58.
31. Rohmann S, Schott RJ, Halting J, Schaper W. Ischemic preconditioning is not a function of stunned myocardium (abstract). J Mol Cell Cardiol 1991;23(suppl V):S71.
32. Rouslin W, Pullman ME. Protonic inhibition of the mitochondrial adenosine 5’-triphosphatase in ischemic cardiac muscle. Reversible binding of the ATPase inhibitor protein to the mitochondrial ATPase during ischemia. J Mol Cell Cardiol 1987;19:661-8.
33. Jennings RB, Reimer KA, Steenbergen C. Effect of inhibition of the mitochondrial ATPase on net myocardial ATP in total ischemia. J Mol Cell Cardiol 1991;23:1383-95.
34. Yellon DM, Downey JM. Current research views on myocardial reperfusion and reperfusion injury. Cardioscience 1990;1:89-98.
35. Bolli R. Mechanism of myocardial stunning. Circulation 1990;82:723-38.
36. Murry CE, Richard VJ, Jennings RB, Reimer KA. Preconditioning with ischaemia: is the protective effect mediated by free radical induced myocardial stunning? (abstract) Circulation 1988; 78(suppl II):77.
37. Iwamoto T, Miura T, Adachi T, et al. Myocardial infarct size-limiting effect of ischemic preconditioning was not attenuated by oxygen free radical scavengers in the rabbit. Circulation 1991; 83:1015-22.
38. Yellon DM, Latchman DS. Stress proteins and myocardial protection. J Mol Cell Cardiol 1992;24:113-24.
39. Lindquist S, Craig EA. The heat shock proteins Annu Rev Genet 1986;22:631-7.
40. Currie RW, Ross BM, Davis TA. Heat shock response is associated with enhanced post ischaemic ventricular recovery. Circ Res 1988;63:543-9.
41. Pasini E, Cargoni A, Ferrari R, Marber MS, Latchman DS, Yellon DM. Heat stress and oxidative damage following ischaemia and reperfusion in the isolated rat heart (abstract). Eur Heart J 1991;12S:P1568.
42. Yellon DM, Pasini E, Ferrari R, Downey JM, Latchman DS. Whole body heat stress protects the isolated perfused rabbit heart (abstract). Circulation 1990;82(suppl III):463.
43. Walker DM. Kucukoglu S, Pasini E, Marber MS, Latchman DS, Yellon DM. The effect of heat stress on infarct size in blood versus buffer perfused rabbit hearts (abstract). J Mol Cell Cardiol 1992;24(suppl I):S118.
44. Donnelly TJ, Sievers RE, Vissent FU, Welch WJ, Wolfe CL. Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion? Circulation 1992;85:769-78.
45. Schott RJ, Nao B, Strieter R, et al. Heat shock does not precondition canine myocardium (abstract). Circulation 1990; 82(suppl III):464.
46. Yellon DM, Pasini E, Cargnoni A, Marber MS, Latchman DS, Ferrari R. The protective role of heat stress in the ischaemic and reperfused rabbit myocardium. J Mol Cell Cardiol 1992 (in press).
47. Thornton J, Striplin S, Liu GS, et al. Inhibition of protein synthesis does not block myocardial protection afforded by preconditioning. Am J Physiol 1990;259(Heart Circ Physiol 28): H1822-5.
48. Iliodromitis E, Kucukoglu S, Marber MS, Walker JM, Yellon DM. Preconditioning protects rabbit heart independent of stress protein synthesis (abstract). Eur Heart J 1991;12S:P720.
49. Heads RJ, Patel VC, Latchman DS, Yellon DM. Ischaemic preconditioning causes rapid elevation of 65kDa stress protein in rabbit heart (abstract). J Mol Cell Cardiol 1992;24(suppl I):S94.
50. Parratt JR, Coker SJ, Wainwright CL. Eicosanoids and susceptability to ventricular arrhythmias during myocardial ischaemia and reperfusion. J Mol Cell Cardiol 1987;19:55-6.
51. Vegh A, Szekeres L, Parratt JR. Does nitric oxide play a role in ischaemic preconditioning? (abstract) J Mol Cell Cardiol 1991; 23(suppl V):S72.
52. Patel V, Woolfson RG, Singh KJ, Neild GH, Yellon DM. Ischaemic preconditioning is not prevented by inhibition of endothelium-derived nitric oxide. J Mol Cell Cardiol 1992;24(suppl I):S152.
53. Stiles GL, Adenosine receptors: physiological regulation and biochemical mechanisms. News Physiol Sci 1991;6:161-4.
54. Wyatt DA, Edmunds MC, Rubio R, Berne RM, Lasley RD, Mentzer RM. Adenosine stimulates glycolytic flux in isolated perfused rat hearts by Al-adenosine receptors. Am J Phvsiol 1989;257(Heart Circ Physiol 26):H1952-7.
55. Liu GS, Thornton J, Van Winkle DM, Stanley AWH, Olsson RA, Downey JM. Protection against infarction afforded by preconditioning is mediated by Al adenosine receptors in rabbit heart. Circulation 1991;84:350-6.
56. Thornton J, Liu GS, Olsson RA, Downey JM. Intravenous pretreatment with Al-selective adenosine analogues protects the heart against infarction. Circulation 1992;85:659-65.
57. Van Winkle DM, Davis RF. Ischemic preconditioning of myocardium: Effect of the adenosine agonist phenylisopropyl adenosine (PIA) (abstract). Circulation 1991;84(suppl II):305.
58. Tsuchida A, Miura T, Iimura O. Role of adenosine receptor activation in infarct size limitation by preconditioning in the heart (abstract). Circulation 1991;84(suppl II):191.
59. Thornton J, Downey JM. G, proteins are involved in preconditioning’s protective effect (abstract). Circulation 1991; 84(suppl II): 192.
60. Lasley RD, Barakat O, Van Wylen DGL, Mentzer RM. Pertussis toxin inhibits adenosine mediated preservation of post-ischaemic myocardial function (abstract). Circulation 1991;84(suppl II): 307.
61. Jennings RB, Murry CE, Reimer KA Myocardial effects of brief periods of ischemia followed by reperfusion. In: Kelleremann, JJ Braunwald E, eds. Silent myocardial ischaemia: a critical appraisal (Advances in Cardiology, vol 37). Basel: Karger, 1990:7-31.
62. Opie LH. Hypothesis: glycolytic rates control cell viability in ischaemia. J Appl Cardiol 1988;3:407-14.
63. Weiss J, Hiltbrand B. Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit heart. J Clin Invest 1985;75:436-47.
64. Fralix TA, Murphy E, Steenbergen C, London RE. Role of glycolysis in preconditioning (abstract). Circulation 1991;84(suppl II): 192.
65. + channels in cardiac muscle. Nature 1983;305:147-8.
66. Grover GJ, McCullough JR, Henry DE, Conder ML, Sleph PG. The anti-ischemic effects of the potassium channel activators pinacidil and cromakalim and the reversal of these effects with the potassium channel blocker glyburide. J Pharmacol Exp Ther 1989;251:98-110.
67. + channels protect the myocardium against ischemia/reperfusion damage. Circ Res 1991;69:571-81.
68. Mitani A, Kinoshita K, Fukamachi K, et al. Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts. Am J Physiol 1991;261(Heart Circ Physiol 30):H1864-71.
69. Grover GJ, Dwonczyk S, Parham CS, Sleph PG. The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated rat hearts and anesthetized dogs. Cardiovasc Drugs Ther 1990;15:465-74.
70. Nichols CG, Lederer WJ. Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. Am J Physiol 1991;261(Heart Circ Physiol 30):H1675-86.
71. + channel activity in intact and permeabilized rat ventricular myocytes. J Physiol (Lond) 1990;423:91-110.
72. Nichols, CG, Ripoll C, Lederer WJ. Katp channel modulation of the guinea-pig ventricular action potential and contraction. Circ Res 1991;68:280-7.
73. + channels to Al receptors by G proteins in rat ventricular myocytes Am J Physiol 1990;259(Heart Circ Physiol 28):H820-6.
74. Auchampach JA, Grover GJ, Gross GJ. The ischemia selective ATP-sensitive K+ channel antagonist, sodium 5-hydroxydecanoate, blocks myocardial preconditioning in dogs (abstract). Circulation 1991;84(suppl II):432.
75. Gross GJ, Auchampach JA. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res 1992;70:223-33.
76. + channels does not prevent preconditioning in rabbit heart (abstract). Circulation 1991;84(suppl IV):432.
77. Chi L, Uprichard ACG, Lucchesi BR. Profibrillatory actions of pinacidil in a conscious canine model of sudden coronary death. J Cardiovasc Pharmacol 1990;15:452-64.
78. Wolleben CD, Sanguinetti MC, Siegl PKS. Influence of ATP-sensitive potassium chanel modulators on ischaemia induced fibrillation in isolated rat hearts. J Mol Cell Cardiol 1989; 21: 783-8.
79. Muller DWM, Topol EJ, Califï RM, et al and the T.A.M.I. Study Group. Relationship between antecedent angina pectoris and short-term prognosis after thrombolytic therapy for acute myocardial infarction. Am Heart J 1990;119:224-31.
80. Deutsch E, Berger M, Kussmaul WG, Hirshfeld JW, Herrmann HC, Laskey WK. Adaptation to ischemia during percutaneous transluminal coronary angioplasty: clinical hemodynamic and metabolic features. Circulation 1990;82:2044-51.