Optimal control of batch processes involving simultaneous enzymatic and microbial reactions

Bioprocess Engineering

Volumn 14, Issue 6, 1996, Pages 323-329

  Asenjo, J A ^a   Sun, W H ^b   Spencer, J L ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; ENZYME KINETICS; FERMENTATION; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL;

EID: 85047679523     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00369477     Document Type: Article

References (14)

1. Asenjo, J.A.; Sun, W-H.; Spencer, J.L.: Optimization of batch processes involving simultaneous enzymatic and microbial reactions. Biotech. Bioeng. 37 (1991) 1087-1094
2. Constantinides, A.; Spencer, J.L.; Gaden, E.L.: Optimization of batch fermentation processes: Development of models for batch penicillin fermentations. Biotech. Bioeng. 12 (1970) 803-830
3. Cazzador, L.: On the optimal control of fed-batch reactors with substrate-inhibited kinetics. Biotech. Bioeng. 31 (1988) 670-674
4. San, K.Y.; Stephanopoulos, G.: A note on the optimality criteria maximum biomass production in a fed-batch fermentor. Biotech. Bioeng. 26 (1984) 1261-1264
5. San, K.Y.; Stephanopoulos, G.: Optimization of fed-batch penicillin fermentation: A case of singular optimal control. Biotech. Bioeng. 28 (1986) 72-78
6. Cuthrell, J.E.; Biegler, L.T.: Simultaneous optimization and solution methods for batch reactor control profiles. Comp. Chem. Engg. 13(1/2) (1989) 49-62
7. Lim, H.C.; Tayeb, Y.J.; Modak, J.M.; Bonte, P.: Computational algorithms for optimal feed rates for a class of fed-batch fermentations: Numerical results for penicillin and cell mass production. Biotech. Bioeng. 28 (1986) 1408-1420
8. Kurtanjek Z.: Optimal nonsingular control of fed-batch fermentation. Biotech. Bioeng. 37 (1991) 814-823
9. Luus, J.: Optimization of fed-batch fermentors by iterative dynamic programming. Communication to the Editor, Biotech. Bioeng. 41 (1993) 599-602
10. Lee, J.; Ramirez, W.F.: Optimal fed-batch control of induced foreign protein production by recombinant bacteria. AIChE J. 40 (1994) 899-907
11. Denn, M.: Optimization by variational methods. New York: McGraw-Hill 1969
12. Lewis, F.L.: Optimal Control. New York: John Wiley and Sons 1986
13. Bryson, A.E.; Ho, Y-C.: Applied Optimal Control. New York: Hemisphere Publishing 1986
14. Sun, W-H.: Optimization of batch simultaneous enzymatic and microbial reaction processes. Doctoral dissertation, Columbia University, 1989