메뉴 건너뛰기




Volumn 19, Issue 5, 1998, Pages 363-372

Performance study of perfusion cultures for the production of single- chain urokinase-type plasminogen activator (scu-PA) in a 2.5 l spin-filter bioreactor

Author keywords

[No Author keywords available]

Indexed keywords

UROKINASE;

EID: 85047678943     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00009024     Document Type: Article
Times cited : (10)

References (26)
  • 1
    • 0021632355 scopus 로고
    • Kidney plasminogen activator: A precursor form of human urokinase with high fibrin affinity
    • Kohno, T.; Hopper, P.; Lillquist, J.S.; Suddith, R.L.; Greenlee, R.; Moir, D.T.: Kidney plasminogen activator: a precursor form of human urokinase with high fibrin affinity. Bio/ Technol. 2 (1984) 628-638
    • (1984) Bio/ Technol. , vol.2 , pp. 628-638
    • Kohno, T.1    Hopper, P.2    Lillquist, J.S.3    Suddith, R.L.4    Greenlee, R.5    Moir, D.T.6
  • 2
    • 0027320826 scopus 로고
    • Comparison of the in vitro fibrinolytic activities of low and high molecular weight single-chain urokinase-type plasminogen activator
    • Munk, G.A.W.; Groeneveld, E.; Rijken, D.C.: Comparison of the in vitro fibrinolytic activities of low and high molecular weight single-chain urokinase-type plasminogen activator. Thromb. Haemostas. 70 (1993) 481-485
    • (1993) Thromb. Haemostas. , vol.70 , pp. 481-485
    • Munk, G.A.W.1    Groeneveld, E.2    Rijken, D.C.3
  • 3
    • 0025678648 scopus 로고
    • Chinese hamster ovary cells continuously secrete a cysteine endopeptidase
    • Satoh, M.; Hosoi, S.; Sato, S.: Chinese hamster ovary cells continuously secrete a cysteine endopeptidase. In Vitro 26 (1990) 1101-1104
    • (1990) In Vitro , vol.26 , pp. 1101-1104
    • Satoh, M.1    Hosoi, S.2    Sato, S.3
  • 4
    • 2442550595 scopus 로고
    • Kinetics of prourokinase production by mammalian cells in culture
    • R.E. Spier, and J.B. Griffiths, (eds.). Butterworth, Somerset, UK
    • Hu, W.-S.; Tao, T.Y.; Bohn, M.A.; Ji, G.Y.: Kinetics of prourokinase production by mammalian cells in culture. In: R.E. Spier, and J.B. Griffiths, (eds.), Modern approaches to animal cell technology, pp. 365-380. Butterworth, Somerset, UK. 1987
    • (1987) Modern Approaches to Animal Cell Technology , pp. 365-380
    • Hu, W.-S.1    Tao, T.Y.2    Bohn, M.A.3    Ji, G.Y.4
  • 5
  • 6
    • 11944254486 scopus 로고
    • Spin filter perfusion system for high density cell culture: Production of recombinant urinary type plasminogen activator in CHO cells
    • Avgerinos, G.C.; Drapeau, D.; Socolow, J.S.; Mao, J.; Hsiao, K.; Broeze, R.J.: Spin filter perfusion system for high density cell culture: production of recombinant urinary type plasminogen activator in CHO cells. Bio/Technol. 8 (1990) 54-58
    • (1990) Bio/Technol. , vol.8 , pp. 54-58
    • Avgerinos, G.C.1    Drapeau, D.2    Socolow, J.S.3    Mao, J.4    Hsiao, K.5    Broeze, R.J.6
  • 7
    • 0027134293 scopus 로고
    • Stable production of recombinant prourokinase by human lymphoblastoid Namalwa KJM-1 cells: Host-cell dependency of the expressed-protein stability
    • Satoh, M.; Hosoi, S.; Miyaji, H.; Itoh, S.; Sato, S.: Stable production of recombinant prourokinase by human lymphoblastoid Namalwa KJM-1 cells: Host-cell dependency of the expressed-protein stability. Cytotechnol. 13 (1993) 79-88
    • (1993) Cytotechnol. , vol.13 , pp. 79-88
    • Satoh, M.1    Hosoi, S.2    Miyaji, H.3    Itoh, S.4    Sato, S.5
  • 8
    • 0028961625 scopus 로고
    • Production of recombinant proteins in Chinese Hamster Ovary Cells using a protein-free cell culture medium
    • Zang, M.; Trautmann, H.; Gandor, C.; Messi, F.; Asselbergs, F.; Leist, C.; Fiechter, A.; Reiser, J.: Production of recombinant proteins in Chinese Hamster Ovary Cells using a protein-free cell culture medium. Bio/Technol. 13 (1995) 389-392
    • (1995) Bio/Technol. , vol.13 , pp. 389-392
    • Zang, M.1    Trautmann, H.2    Gandor, C.3    Messi, F.4    Asselbergs, F.5    Leist, C.6    Fiechter, A.7    Reiser, J.8
  • 9
    • 0020973798 scopus 로고
    • Large-scale production of mammalian cells and their products: Engineering principles and barriers to scale-up
    • Glacken, M.W.; Fleischaker, R.J.; Sinskey, A.J.: Large-scale production of mammalian cells and their products: engineering principles and barriers to scale-up. Ann. N.Y. Acad. Sci. 413 (1983) 355-372
    • (1983) Ann. N.Y. Acad. Sci. , vol.413 , pp. 355-372
    • Glacken, M.W.1    Fleischaker, R.J.2    Sinskey, A.J.3
  • 10
    • 0027463528 scopus 로고
    • Cell-cell adhesion and aggregation: Influence on the growth behavior of CHO cells
    • Renner, W.A.; Jordan, M.; Eppenberger, H.M.; Leist, C.: Cell-cell adhesion and aggregation: influence on the growth behavior of CHO cells. Biotechnol. Bioeng. 41 (1993) 188-193
    • (1993) Biotechnol. Bioeng. , vol.41 , pp. 188-193
    • Renner, W.A.1    Jordan, M.2    Eppenberger, H.M.3    Leist, C.4
  • 11
    • 9544224252 scopus 로고    scopus 로고
    • Production of tissue plasminogen activator in two and three dimensionally growing cultures of Bowes melanoma cells
    • Brenner, J.; Hülser, D.F.: Production of tissue plasminogen activator in two and three dimensionally growing cultures of Bowes melanoma cells. Biotechnol. Bioeng. 51 (1996) 422-433
    • (1996) Biotechnol. Bioeng. , vol.51 , pp. 422-433
    • Brenner, J.1    Hülser, D.F.2
  • 12
    • 0346076455 scopus 로고
    • Large scale culture of hybridoma and mammalian cells in fluidized bed bioreactors
    • M. Moo-Young (ed.). Elsevier, New York
    • Dean, R.C. Jr.; Karkare, S.B.; Ray, N.G.; Runstadler, P.W.; Vankatasubramanian, J.: Large scale culture of hybridoma and mammalian cells in fluidized bed bioreactors. pp. 125-142. In: M. Moo-Young (ed.), Immobilized enzymes and cells. Elsevier, New York. 1988
    • (1988) Immobilized Enzymes and Cells , pp. 125-142
    • Dean Jr., R.C.1    Karkare, S.B.2    Ray, N.G.3    Runstadler, P.W.4    Vankatasubramanian, J.5
  • 15
    • 0030571271 scopus 로고    scopus 로고
    • Two-dimensional versus three dimensional culture systems: Effects on growth and productivity of BHK cells
    • Alves, P.M.; Moreira, J.L.; Rodrigues, J.M.; Aunins, J.G.; Carrondo, M.J.T.: Two-dimensional versus three dimensional culture systems: effects on growth and productivity of BHK cells. Biotechnol. Bioeng. 52 (1996) 429-432
    • (1996) Biotechnol. Bioeng. , vol.52 , pp. 429-432
    • Alves, P.M.1    Moreira, J.L.2    Rodrigues, J.M.3    Aunins, J.G.4    Carrondo, M.J.T.5
  • 16
    • 0029198092 scopus 로고
    • The optimization of serum-free media for the production of the scu-PA by the addition of algal extracts
    • Kim, H.G.; Sung, K.D.; Ham, M.S.; Chung, K.H.; Chung, K.H.; Lee, H.Y.: The optimization of serum-free media for the production of the scu-PA by the addition of algal extracts. Cytotechnol. 17 (1995) 165-172
    • (1995) Cytotechnol. , vol.17 , pp. 165-172
    • Kim, H.G.1    Sung, K.D.2    Ham, M.S.3    Chung, K.H.4    Chung, K.H.5    Lee, H.Y.6
  • 17
    • 0028121775 scopus 로고
    • High-density culture of mammalian cells with dynamic perfusion based on on-line oxygen uptake rate measurements
    • Kyung, Y.-S.; Peshwa, M.V.; Gryte, D.M.; Hu, W.-S.: High-density culture of mammalian cells with dynamic perfusion based on on-line oxygen uptake rate measurements. Cytotechnol. 14 (1994) 183-190
    • (1994) Cytotechnol. , vol.14 , pp. 183-190
    • Kyung, Y.-S.1    Peshwa, M.V.2    Gryte, D.M.3    Hu, W.-S.4
  • 18
    • 0028979470 scopus 로고
    • On-line gas analysis in animal cell cultivation: I. Control of dissolved oxygen and pH
    • Oeggerli, A.; Eyer, K.; Heinzle, E.: On-line gas analysis in animal cell cultivation: I. Control of dissolved oxygen and pH. Biotechnol. Bioeng. 45 (1995a) 42-53
    • (1995) Biotechnol. Bioeng. , vol.45 , pp. 42-53
    • Oeggerli, A.1    Eyer, K.2    Heinzle, E.3
  • 19
    • 0029635979 scopus 로고
    • On-line gas analysis in animal cell cultivation: II. Methods for oxygen uptake rate estimation and its application to controlled feeding of glutamine
    • Oeggerli, A.; Eyer, K.; Heinzle, E.: On-line gas analysis in animal cell cultivation: II. Methods for oxygen uptake rate estimation and its application to controlled feeding of glutamine. Biotechnol. Bioeng. 45 (1995b) 54-62
    • (1995) Biotechnol. Bioeng. , vol.45 , pp. 54-62
    • Oeggerli, A.1    Eyer, K.2    Heinzle, E.3
  • 20
    • 0030038110 scopus 로고    scopus 로고
    • Control of long-term perfusion Chinese hamster ovary cell culture by glucose auxostat
    • Konstantinov, K.B.; Tsai, Y.-S.; Moles, D.; Matanguihan, R.: Control of long-term perfusion Chinese hamster ovary cell culture by glucose auxostat. Biotechnol. Prog. 12 (1996) 100-129
    • (1996) Biotechnol. Prog. , vol.12 , pp. 100-129
    • Konstantinov, K.B.1    Tsai, Y.-S.2    Moles, D.3    Matanguihan, R.4
  • 21
    • 0029839957 scopus 로고    scopus 로고
    • On-line measurement of oxygen uptake in cell culture using the dynamic method
    • Singh, V.: On-line measurement of oxygen uptake in cell culture using the dynamic method. Biotechnol. Bioeng. 52 (1996) 443-448
    • (1996) Biotechnol. Bioeng. , vol.52 , pp. 443-448
    • Singh, V.1
  • 22
    • 0342547017 scopus 로고    scopus 로고
    • Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor
    • Ozturk, S.S.; Thrift, J.C.; Blackie, J.D.; Naveh, D.: Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor. Biotechnol. Bioeng. 53 (1997) 372-378
    • (1997) Biotechnol. Bioeng. , vol.53 , pp. 372-378
    • Ozturk, S.S.1    Thrift, J.C.2    Blackie, J.D.3    Naveh, D.4
  • 23
    • 0022387786 scopus 로고
    • Proteolytic cleavage of single-chain pro-urokinase induces conformational change which follows activation of the zymogen and reduction of its high affinity for fibrin
    • Kasai, S.; Arimura, H.; Nishida, M.; Suyama, T.: Proteolytic cleavage of single-chain pro-urokinase induces conformational change which follows activation of the zymogen and reduction of its high affinity for fibrin. J. Biol. Chem. 260 (1985) 12377-12381
    • (1985) J. Biol. Chem. , vol.260 , pp. 12377-12381
    • Kasai, S.1    Arimura, H.2    Nishida, M.3    Suyama, T.4
  • 24
    • 0001127374 scopus 로고
    • Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity
    • Urlaub, G.; Chasin, L.A.: Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc. Natl. Acad. Sci. 77 (1980) 4216-4220
    • (1980) Proc. Natl. Acad. Sci. , vol.77 , pp. 4216-4220
    • Urlaub, G.1    Chasin, L.A.2
  • 25
    • 0020400592 scopus 로고
    • Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA gene
    • Kaufman, R.J.; Sharp, P.A.: Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA gene. J. Mol. Biol. 159 (1982) 610-621
    • (1982) J. Mol. Biol. , vol.159 , pp. 610-621
    • Kaufman, R.J.1    Sharp, P.A.2
  • 26
    • 1842297541 scopus 로고    scopus 로고
    • The effect of dissolved oxygen on the metabolic profile of a murine hybridoma grown in serum-free medium in continuous culture
    • Jan, D.C.H.; Petch, D.A.; Huzel, N.; Butler, M.: The effect of dissolved oxygen on the metabolic profile of a murine hybridoma grown in serum-free medium in continuous culture. Biotechnol. Bioeng. 54 (1997) 153-164
    • (1997) Biotechnol. Bioeng. , vol.54 , pp. 153-164
    • Jan, D.C.H.1    Petch, D.A.2    Huzel, N.3    Butler, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.