Adenosine A1 receptors mediate hypoxia-induced inhibition of electrically evoked transmitter release from rat striatal slices

European Journal of Pharmacology

Volumn 329, Issue 2-3, 1997, Pages 107-113

  Jin, Shaoyu ^a   Fredholm, Bertil B ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adenosine A1; Hypoxia; Purine; Receptor; Striatum; Transmitter release; Xanthine

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ACETYLCHOLINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; CHOLINE; DOPAMINE; HYPOXANTHINE; INOSINE; RADIOISOTOPE; 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; ADENOSINE RECEPTOR; XANTHINE DERIVATIVE;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; ELECTROSTIMULATION; HYPOXIA; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN HYPOXIA; DRUG ANTAGONISM; METABOLISM; PH; SPRAGUE DAWLEY RAT;

ACETYLCHOLINE; ADENOSINE; ANIMALS; CORPUS STRIATUM; DOPAMINE; ELECTRIC STIMULATION; HYDROGEN-ION CONCENTRATION; HYPOXIA, BRAIN; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1; XANTHINES;

EID: 85047678934     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)89172-8     Document Type: Article

References (8)

1. Benveniste, H., Drejer, J., Schousboe, A., Diemer, N.H., 1984. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43, 1369-1374.
2. Brannan, T., Weinberger, J., Knott, P., Taff, I., Kaufmann, H., Togasaki, D., Nieves-Rosa, J., Maker, H., 1987. Direct evidence of acute, massive striatal dopamine release in gerbils with unilateral strokes. Stroke 18, 108-110.
3. 14C]acetylcholine release from rat cortex. J. Pharmacol. Exp. Ther. 277, 193-197.
4. Duffy, T.E., Nelson, S.R., Lowry, O.H., 1972. Cerebral carbohydrate metabolism during acute hypoxia and recovery. J. Neurochem. 19, 959-977.
5. Fowler, J.C., 1990. Adenosine antagonists alter the synaptic response to in vitro ischemia in the rat hippocampus. Brain Res. 509, 331-334.
6. Fowler, J.C., 1993. Purine release and inhibition of synaptic transmission during hypoxia and hypoglycemia in rat hippocampal slices. Neurosci. Lett. 157, 83-86.
7. 3H]-acetylcholine release from rat hippocampus. J. Neurochem. 54, 1386-1390.
8. Fredholm, B.B., 1996. Adenosine and neuroprotection. In: Green, A.R., Cross, A.J. (Eds.), Neuroprotective Agents and Cerebral Ischemia. Academic Press, London, pp. 259-280.