Activin regulates βA-subunit and activin receptor messenger ribonucleic acid and cellular proliferation in activin-responsive testicular tumor cells

Endocrinology

Volumn 139, Issue 3, 1998, Pages 1147-1155

  Di Simone, Nicoletta ^a   Hall, H Alexander ^a   Welt, Corrine ^a   Schneyer, Alan L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; ACTIVIN RECEPTOR; INHIBIN; FOLLISTATIN; GLYCOPROTEIN; GROWTH FACTOR RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL PROLIFERATION; DOWN REGULATION; EMBRYO DEVELOPMENT; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TESTIS TUMOR; TUMOR CELL CULTURE; TUMOR DIFFERENTIATION; ANIMAL; CELL CULTURE; CELL DIVISION; GENETICS; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECRETION;

ACTIVIN RECEPTORS; ACTIVINS; ANIMALS; CELL DIVISION; FOLLISTATIN; GLYCOPROTEINS; INHIBINS; MALE; MICE; RECEPTORS, GROWTH FACTOR; RNA, MESSENGER; TESTICULAR NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 85047677687     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.3.5800     Document Type: Article

References (54)

1. Ying SY 1988 Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone. Endocr Rev 9:267-293
2. Vale W, Rivier C, Hsueh A, et al 1988 Chemical and biological characterization of the inhibin family of protein hormones. Recent Prog Horm Res 44:1-34
3. DeKretser DM, Robertson DM 1989 The isolation and physiology of inhibin and related proteins. Biol Reprod 40:33-47
4. Mather JP, Woodruff TK, Krummen LA 1992 Paracrine regulation of reproductive function by inhibin and activin. Proc Soc Exp Biol Med 201:1-15
5. Chen CL 1993 Inhibin and activin as paracrine/autocrine factors. Endocrinology 132:4-5 (Editorial Comment)
6. Roberts V, Meunier H, Sawchenko PE, Vale W 1989 Differential production and regulation of inhibin subunits in rat testicular cell types. Endocrinology 125:2350-2359
7. Morris PL, Vale W, Cappel S, Bardin CW 1988 Inhibin production by primary Sertoli cell-enriched cultures: regulation by follicle-stimulating hormone, androgens, and epidermal growth factor. Endocrinology 122:717-725
8. Bicsak TA, Vale W, Vaughan J, Tucker EM, Cappel S, Hsueh AJW 1987 Hormonal regulation of inhibin production by cultured Sertoli cells. Mol Cell Endocrinol 49:211-217
9. Grootenhuis AJ, Timmerman MA, Hordijk PL, De Jong FH 1990 Inhibin in immature rat Sertoli cell conditioned medium: A 32 kDa alpha/beta-B dimer. Mol Cell Endocrinol 70:109-116
10. van Dissel-Emiliani FM, Grootenhuis AJ, De Jong FH, de Rooij DG 1989 Inhibin reduces spermatogonial numbers in testes of adult mice and Chinese hamsters. Endocrinology 125:1899-1903
11. Hsueh AJW, Dahl KD, Vaughan J, et al 1987 Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis. Proc Natl Acad Sci USA 84:5082-5086
12. Grootenhuis AJ, Steenbergen J, Timmerman MA, Dorsman ANRD, Schaaper WMM 1989 Inhibin and activin-like activity in fluids from male and female gonads: different molecular weight forms and bioactivity to immunoactivity ratios. J Endocrinol 122:293-301
13. Bhasin S, Krummen LA, Swerdloff RS, et al 1989 Stage dependent expression of inhibin α and β-B subunits during the cycle of the rat seminiferous epithelium. Endocrinology 124:987-991
14. Mather JP, Attie KM, Woodruff TK, Rice GC, Phillips DM 1990 Activin stimulates spermatogonial proliferation in germ-Sertoli cell cocultures from immature rat testis. Endocrinology 127:3206-3214
15. Mather JP, Roberts PE, Krummen LA 1993 Follistatin modulates activin activity in a cell-and tissue-specific manner. Endocrinology 132:2732-2734
16. Roberts VJ, Barth SL 1994 Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid-and late-gestation rat embryogenesis. Endocrinology 134:914-923
17. Roberts VJ, Sawchenko PE, Vale W 1991 Expression of inhibin/activin subunit messenger ribonucleic acids during rat embryogenesis. Endocrinology 128:3122-3129
18. Kaipia A, Penttila T-L, Shimasaki S, Ling N, Parvinen M, Toppari J 1992 Expression of inhibin β-A and β-B, follistatin and activin-A receptor mRNAs in the rat seminiferous epithelium. Endocrinology 131:2703-2710
19. Kaipia A, Parvinen M, Toppari J 1993 Localization of activin receptor (ActR-IIB2) mRNA in the rat seminiferous epithelium [see comments]. Endocrinology 132:477-479
20. Cameron VA, Nishimura N, Mathews LS, Lewis KA, Sawchenko PE, Vale WW 1994 Hybridization histochemical localization of activin receptor subtypes in rat brain, pituitary, ovary, and testis. Endocrinology 134:799-808
21. Nakamura T, Takio K, Eto Y, Shibai H, Titani K, Sugino H 1990 Activin-binding protein from rat ovary is follistatin. Science 247:836-838
22. DePaolo LV, Bicsak TA, Erickson GF, Shimasaki S, Ling N 1991 Follistatin and activin: a potential intrinsic regulatory system within diverse tissues. Proc Soc Exp Med 198:500-512
23. Schneyer AL, O'Neil DA, Crowley WF 1992 Activin-binding proteins in human serum and follicular fluids. J Clin Endocrinol Metab 74:1320-1324
24. Schneyer AL, Hall HA, Lambert-Messerlian GM, Wang QF, Sluss PM, Crowley WF 1996 Follistatin-activin complexes in human serum and follicular fluid differ immunologically and biochemically. Endocrinology 137:240-247
25. Khoury RH, Wang QF, Crowley WF, Hall JE, Schneyer AL, Toth T, Midgley AR, Sluss PM 1995 Serum follistatin levels in women: evidence against an endocrine function of ovarian follistatin. J Clin Endocrinol Metab 80:1361-1368
26. Krummen LA, Woodruff TK, DeGuzman G, et al 1993 Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids. Endocrinology 132:431-443
27. Kogawa K, Nakamura T, Sugino K, Takio K, Titani K, Sugino H 1991 Activin-binding protein is present in pituitary. Endocrinology 128:1434-1440
28. Schneyer A, Rzucidlo DA, Sluss PM, Crowley Jr WF 1994 Characterization of unique binding kinetics of follistatin and activin or inhibin in serum. Endocrinology 135:667-674
29. Mathews LS 1995 Activin receptors and cellular signaling by the receptor serine kinase family. Endocr Rev 15:310-341
30. Massague J 1996 TGF-β signaling: receptors, transducers, and Mad proteins. Cell 85:947-950
31. Matzuk MM, Finegold MJ, Su JJ, Hsueh AJW, Bradley A 1992 α-Inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360:313-319
32. Shikone T, Matzuk MM, Perlas E, et al 1994 Characterization of gonadal sex cord-stromal tumor cell lines from inhibin α and p53-deficient mice: the role of activin as an autocrine growth factor. Mol Endocrinol 8:983-995
33. Groome N, Lawrence M 1991 Preparation of monoclonal antibodies to the β-A subunit of ovarian inhibin using a synthetic peptide immunogen. Hybridoma 10:309-316
34. Knight PG, Muttukrishna S, Groome NP 1996 Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-A concentrations in serum and follicular fluid. J Endocrinol 148:267-279
35. Lambert-Messerlian GM, Hall JE, Sluss PM, Taylor AE, Martin KM, Groome NP, Crowley WF, Schneyer AL 1994 Relatively low levels of dimeric inhibin circulate in men and women with polycystic ovarian syndrome using a specific two-site enzyme-linked immunosorbent assay. J Clin Endocrinol Metab 79:45-50
36. Chomzynski P, Sacchi N 1987 Single step method of RNA isolation by acid guadinium thiocyanate phenol-chloroform extraction. Anal Biochem 162:156-159
37. Bernstein JR, Crowley Jr WF, Schneyer AL 1990 An improved method of purifying inhibin radioligand for radioimmunoassay. Biol Reprod 43:492-496
38. Tsuchida K, Vaughan JM, Wiater E, Gaddy-Kurten D, Vale WW 1995 Inactivation of activin-dependent transcription by kinase-deficient activin receptors. Endocrinology 136:5493-5503
39. Willis SA, Zimmerman CM, Li L, Mathews LS 1996 Formation and activation by phosphorylation of activin receptor complexes. Mol Endocrinol 10:367-379
40. Wang QF, Tilly KI, Tilly JL, et al 1997 Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line LNCaP. Endocrinology 137:5476-5483
41. Trudeau VL, Matzuk MM, Hache RJG, Renaud LP 1994 Overexpression of activin-βA subunit mRNA is associated with decreased activin type II receptor mRNA levels in the testes of α-inhibin deficient mice. Biochem Biophys Res Commun 203:105-112
42. Matzuk MM, Finegold MJ, Mather JP, Krummen L, Lu L, Bradley A 1994 Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice. Proc Natl Acad Sci USA 91:8817-8821
43. Sumitomo S, Inouye S, Liu X, Ling N, Shimasaki S 1995 The heparin binding site of follistatin is involved in its interaction with activin. Biochem Biophys Res Commun 208:1-9
44. Kotajima A, Miyamoto Y, Tsuruo M, Kosaka M, Saito S 1995 Effects of activin A on deoxyribonucleic acid synthesis, iodine metabolism, and cyclic adenosine monophosphate accumulation in porcine thyroid cells. Endocrinology 136:1214-1218
45. Battergay EJ, Raines EW, Seifert RA, Bowen-Pope DF, Ross R 1990 TGF-β induces bimetal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 63:515-524
46. Hakovirta H, Kaipia A, Soder O, Parvinen M 1993 Effects of activin-A, inhibin-A, and transforming growth factor-β1 on stage-specific deoxyribonucleic acid synthesis during rat seminiferous epithelial cycle. Endocrinology 133:1664-1668
47. Attisano L, Wrana JL, Cheifetx S, Massague J 1992 Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/ threonine kinase receptors. Cell 68:97-108
48. Feng ZM, Madigan MB, Chen CL 1993 Expression of type II activin receptor genes in the male and female reproductive tissues of the rat. Endocrinology 132:2593-2600
49. Mason AJ, Schwall R, Renz M, Rhee LM, Nikolics K, Seeburg PH 1986 Human inhibin and activin: structure and recombinant expression in mammalian cells. In: Burger HG, deKretser DM, Findlay JK, Igarashi M (eds) Inhibin-Non-Steroidal Regulation of Follicle Stimulating Hormone Secretion. Raven Press, New York, pp 77-88
50. Albano RM, Groome N, Smith JC 1993 Activins are expressed in preimplantation mouse embryos and in ES and EC cells and are regulated on their differentiation. Development 117:711-723
51. Albano RM, Arkell R, Beddington RS, Smith JC 1994 Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain. Development 120:803-813
52. Donaldson CJ, Mathews LM, Vale WW 1992 Molecular cloning and binding properties of the human type II activin receptor. Biochem Biophys Res Commun 184:310-316
53. Ten Dijke P, Ichijo H, Franzen P, et al 1993 Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. Oncogene 8:2879-2887
54. Ponte P, Ng SY, Engel J, Gunning P, Kedes L 1984 Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human β-actin cDNA. Nucleic Acids Res 12:1687-1696