Learning from a trial stopped by a data and safety monitoring board

New England Journal of Medicine

Volumn 378, Issue 21, 2018, Pages 2031-2032

  Harrington, David ^a   Drazen, Jeffrey M ^b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL DECISION MAKING; CLINICAL EFFECTIVENESS; CLINICAL TRIAL (TOPIC); DEATH; DISEASE EXACERBATION; EDITORIAL; EXTRACORPOREAL OXYGENATION; HEALTH CARE ORGANIZATION; HEALTH CARE PLANNING; HIGH RISK POPULATION; HUMAN; HYPOXEMIA; MORTALITY RISK; PATIENT SAFETY; PRIORITY JOURNAL; RESPIRATORY DISTRESS SYNDROME; TREATMENT OUTCOME; PROFESSIONAL STANDARD;

CLINICAL TRIALS DATA MONITORING COMMITTEES; HUMANS;

EID: 85047375911     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1805123     Document Type: Editorial

References (3)

1. DeMets DL, Ellenberg SS. Data monitoring committees - expect the unexpected. N Engl J Med 2016; 375: 1365-71.
2. Combes A, Hajage D, Capellier G, et al. Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med 2018; 378: 1965-75.
3. Pocock SJ, Stone GW. The primary outcome fails - what next? N Engl J Med 2016; 375: 861-70.