Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains

eLife

Volumn 4, Issue , 2015, Pages

  Bushman, Diane M ^a   Kaeser, Gwendolyn E ^a   Siddoway, Benjamin ^a   Westra, Jurgen W ^a   Rivera, Richard R ^a   Rehen, Stevens K ^a   Yung, Yun C ^a   Chun, Jerold ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

AD; amyloid precursor protein; CNV; human; neuroscience; somatic mosaicism

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DNA; PEPTIDE NUCLEIC ACID;

ALZHEIMER DISEASE; BRAIN CORTEX; CELL NUCLEUS; DOWN SYNDROME; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DOSAGE; GENE LOCUS; GENETICS; GENOME; HUMAN; METABOLISM; MOSAICISM; NERVE CELL; PATHOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; CELL NUCLEUS; CEREBRAL CORTEX; DNA; DOWN SYNDROME; FLOW CYTOMETRY; GENE AMPLIFICATION; GENE DOSAGE; GENETIC LOCI; GENOME; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MOSAICISM; NEURONS; PEPTIDE NUCLEIC ACIDS;

EID: 85047211100     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.05116     Document Type: Article

References (0)