Delivery of antibiotics to the eye using a positively charged polysaccharide as vehicle

AAPS PharmSci

Volumn 3, Issue 4, 2001, Pages

  Felt, O ^a   Baeyens, V ^b,c   Buri, P ^a,b   Gurny, R ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Campus Universitaire   (France)

^c TRB Chemedica   (Switzerland)

Author keywords

Antibiotic; Chitosan; Hydrogel; Ophthalmic application; Pharmacokinetics

Indexed keywords

ANTIBIOTIC AGENT; CHITOSAN; OFLOXACIN; POLYSACCHARIDE; TOBRAMYCIN; ANTIINFECTIVE AGENT; BIOPOLYMER; CHITIN; DRUG DERIVATIVE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORNEA; DEACETYLATION; DISSOCIATION CONSTANT; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; HUMAN; LACRIMAL FLUID; LIPOPHILICITY; MALE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; NONHUMAN; RABBIT; ANIMAL; BIOAVAILABILITY; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG DOSAGE FORM; EYE; METABOLISM; METHODOLOGY; SOLUBILITY; SOLUTION AND SOLUBILITY; TIME; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL AVAILABILITY; BIOPOLYMERS; CHITIN; CHITOSAN; DOSAGE FORMS; DRUG DELIVERY SYSTEMS; EYE; MALE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; OFLOXACIN; RABBITS; SOLUBILITY; SOLUTIONS; TEARS; TIME FACTORS; TOBRAMYCIN; TREATMENT OUTCOME;

EID: 85046915157     PISSN: 15221059     EISSN: None     Source Type: Journal    
DOI: 10.1208/ps030434     Document Type: Article

References (11)

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