Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: Inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process

AAPS PharmSci

Volumn 3, Issue 3, 2001, Pages

  Otsuka, Makoto ^a   Sato, Mitsuyo ^a   Matsuda, Yoshihisa ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Compression; Dissolution; Tableting; Trypsin preparation

Indexed keywords

CELLULOSE; HYDROXYPROPYLCELLULOSE; LACTOSE; LUBRICATING AGENT; MICROCRYSTALLINE CELLULOSE; TRYPSIN;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG FORMULATION; DRUG GRANULATION; DRUG MIXTURE; DRUG POTENCY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; ENZYME INHIBITION; FRICTION; INTERMETHOD COMPARISON; LUBRICATION; POWDER; PRESSURE MEASUREMENT; STATISTICAL ANALYSIS; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET HARDNESS; TABLET MACHINE; TABLET POROSITY; WATER ABSORPTION;

EID: 85046914088     PISSN: 15221059     EISSN: None     Source Type: Journal    
DOI: 10.1208/ps030320     Document Type: Article

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