A new family of sequence-specific DNA-cleaving agents directed by triple-helical structures: Benzopyridoindole-EDTA conjugates

Chemistry - A European Journal

Volumn 6, Issue 9, 2000, Pages 1559-1563

  Marchand, Christophe ^a   Nguyen, Chi Hung ^b   Ward, Brian ^c   Sun, Jian Sheng ^a   Bisagni, Emile ^b   Garestier, Thérèse ^a   Hélène, Claude ^a  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b INSTITUT CURIE   (France)

^c Sigma Chemical Company   (United States)

Author keywords

DNA cleavage; EDTA; Oligonucleotides; Triple helix

Indexed keywords

BENZO[E]PYRIDOINDOLE; BENZO[G]PYRIDOINDOLE; CARBOLINE DERIVATIVE; DNA; DOUBLE STRANDED DNA; EDETIC ACID; INDOLE DERIVATIVE; IRON; OLIGODEOXYRIBONUCLEOTIDE; OXYGEN; REDUCING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CONJUGATION; DNA BINDING; DNA CLEAVAGE; DNA STRAND BREAKAGE; DRUG EFFECT; GENE EXPRESSION REGULATION; MOLECULAR RECOGNITION; PLASMID; STRUCTURE ACTIVITY RELATION; TRIPLE HELIX;

DNA; EDETIC ACID; GENE EXPRESSION REGULATION; INDOLES; IRON; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; PLASMIDS;

EID: 85046527842     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3765(20000502)6:9<1559::AID-CHEM1559>3.3.CO;2-Q     Document Type: Article

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