Treatment with D-β-hydroxybutyrate protects heart from ischemia/reperfusion injury in mice

European Journal of Pharmacology

Volumn 829, Issue , 2018, Pages 121-128

  Yu, Yongsheng ^a   Yu, Yunhua ^b   Zhang, Yuefan ^c   Zhang, Zhigang ^b   An, Weishuai ^a   Zhao, Xianxian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Autophagic flux; D hydroxybutyrate; Ischemia reperfusion; Mitochondrial function; Oxidative stress

Indexed keywords

3 HYDROXYBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; CREATINE KINASE; LACTATE DEHYDROGENASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN LC3 I; MYOSIN LIGHT CHAIN LC3 II; REACTIVE OXYGEN METABOLITE; SEQUESTOSOME 1; TROPONIN I; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CARDIAC MUSCLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG BLOOD LEVEL; ENDOPLASMIC RETICULUM STRESS; HEART FUNCTION; HEART MITOCHONDRION; HEART PROTECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; MOUSE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL PROTECTION; DRUG EFFECT; HEART; METABOLISM; MITOCHONDRION; NECROSIS; PATHOLOGY; PATHOPHYSIOLOGY;

3-HYDROXYBUTYRIC ACID; ANIMALS; APOPTOSIS; CYTOPROTECTION; ENDOPLASMIC RETICULUM STRESS; HEART; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 85046036132     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2018.04.019     Document Type: Article

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