Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition

eLife

Volumn 4, Issue , 2015, Pages

  Kondo, Yasushi ^a   Oubridge, Chris ^a   van Roon, Anne Marie M ^a   Nagai, Kiyoshi ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

5 splice site; biophysics; crystallography; human; pre mRNA splicing; spliceosome; structural biology; U1 snRNP

Indexed keywords

PEPTIDE; PROTEIN BINDING; RNA SPLICING; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA; U1 SMALL NUCLEAR RNA;

CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; RNA SPLICING; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PEPTIDES; PROTEIN BINDING; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; RNA SPLICE SITES; RNA, SMALL NUCLEAR;

EID: 85045755098     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.04986     Document Type: Article

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