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Volumn 20, Issue 4, 2018, Pages 705-715

Fixed-dose vs free-dose combinations for the management of hypertension—An analysis of 81 958 patients

Author keywords

adherence; angiotensin receptor blocker; angiotensin converting enzyme inhibitor; calcium antagonist; fixed dose combination; hypertension

Indexed keywords

AMLODIPINE PLUS CANDESARTAN; AMLODIPINE PLUS RAMIPRIL; ANTIHYPERTENSIVE AGENT; UNCLASSIFIED DRUG; AMLODIPINE; BENZIMIDAZOLE DERIVATIVE; CANDESARTAN; RAMIPRIL; TETRAZOLE DERIVATIVE;

EID: 85045522090     PISSN: 15246175     EISSN: 17517176     Source Type: Journal    
DOI: 10.1111/jch.13240     Document Type: Article
Times cited : (27)

References (32)
  • 1
    • 85006784962 scopus 로고    scopus 로고
    • Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants
    • NCD-RisC. Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants. Lancet. 2017;389:37-55.
    • (2017) Lancet , vol.389 , pp. 37-55
  • 2
    • 85010262671 scopus 로고    scopus 로고
    • Treatment of hypertensive patients with a fixed-dose combination of bisoprolol and amlodipine: results of a cohort study with more than 10,000 patients
    • Hostalek U, Czarnecka D, Koch EMW. Treatment of hypertensive patients with a fixed-dose combination of bisoprolol and amlodipine: results of a cohort study with more than 10,000 patients. Cardiol Ther. 2015;4:179-190.
    • (2015) Cardiol Ther , vol.4 , pp. 179-190
    • Hostalek, U.1    Czarnecka, D.2    Koch, E.M.W.3
  • 3
    • 84922429742 scopus 로고    scopus 로고
    • Randomized evaluation of a novel, fixed-dose combination of perindopril 3.5 mg/amlodipine 2.5 mg as a first-step treatment in hypertension
    • discussion 662
    • Laurent S, Parati G, Chazova I, et al. Randomized evaluation of a novel, fixed-dose combination of perindopril 3.5 mg/amlodipine 2.5 mg as a first-step treatment in hypertension. J Hypertens. 2015;33:653-661; discussion 662.
    • (2015) J Hypertens , vol.33 , pp. 653-661
    • Laurent, S.1    Parati, G.2    Chazova, I.3
  • 4
    • 84919796055 scopus 로고    scopus 로고
    • Fixed-dose combination of losartan and hydrochlorothiazide significantly improves endothelial function in uncontrolled hypertension by low-dose amlodipine: a randomized study
    • Takase B, Nagata M. Fixed-dose combination of losartan and hydrochlorothiazide significantly improves endothelial function in uncontrolled hypertension by low-dose amlodipine: a randomized study. Anadolu Kardiyol Derg. 2014;14:685-691.
    • (2014) Anadolu Kardiyol Derg , vol.14 , pp. 685-691
    • Takase, B.1    Nagata, M.2
  • 5
    • 84928034948 scopus 로고    scopus 로고
    • Efficacy and safety of fixed-dose losartan/hydrochlorothiazide/amlodipine combination versus losartan/hydrochlorothiazide combination in Japanese patients with essential hypertension
    • Rakugi H, Tsuchihashi T, Shimada K, et al. Efficacy and safety of fixed-dose losartan/hydrochlorothiazide/amlodipine combination versus losartan/hydrochlorothiazide combination in Japanese patients with essential hypertension. Clin Exp Hypertens. 2015;37:260-266.
    • (2015) Clin Exp Hypertens , vol.37 , pp. 260-266
    • Rakugi, H.1    Tsuchihashi, T.2    Shimada, K.3
  • 6
    • 84901181128 scopus 로고    scopus 로고
    • Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD
    • Chrysant SG. Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD. Expert Rev Cardiovasc Ther. 2013;11:1115-1124.
    • (2013) Expert Rev Cardiovasc Ther , vol.11 , pp. 1115-1124
    • Chrysant, S.G.1
  • 7
    • 84880015206 scopus 로고    scopus 로고
    • 2013 ESH/ESC Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens. 2013;31:1281-1357.
    • (2013) J Hypertens , vol.31 , pp. 1281-1357
    • Mancia, G.1    Fagard, R.2    Narkiewicz, K.3
  • 8
    • 85019880651 scopus 로고    scopus 로고
    • Risk factors for nonadherence to antihypertensive treatment
    • Gupta P, Patel P, Štrauch B, et al. Risk factors for nonadherence to antihypertensive treatment. Hypertension. 2017;69:1113-1120.
    • (2017) Hypertension , vol.69 , pp. 1113-1120
    • Gupta, P.1    Patel, P.2    Štrauch, B.3
  • 10
    • 74949125742 scopus 로고    scopus 로고
    • Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis
    • Gupta AK, Arshad S, Poulter NR. Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis. Hypertension. 2010;55:399-407.
    • (2010) Hypertension , vol.55 , pp. 399-407
    • Gupta, A.K.1    Arshad, S.2    Poulter, N.R.3
  • 12
    • 33746943233 scopus 로고    scopus 로고
    • Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures
    • Hess LM, Raebel MA, Conner DA, Malone DC. Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures. Ann Pharmacother. 2006;40:1280-1288.
    • (2006) Ann Pharmacother , vol.40 , pp. 1280-1288
    • Hess, L.M.1    Raebel, M.A.2    Conner, D.A.3    Malone, D.C.4
  • 13
    • 84867213058 scopus 로고    scopus 로고
    • Prevalence of comorbid conditions with aging among patients with diabetes and cardiovascular disease
    • Davis JW, Chung R, Juarez DT. Prevalence of comorbid conditions with aging among patients with diabetes and cardiovascular disease. Hawaii Med J. 2011;70:209-213.
    • (2011) Hawaii Med J , vol.70 , pp. 209-213
    • Davis, J.W.1    Chung, R.2    Juarez, D.T.3
  • 14
    • 77957336037 scopus 로고    scopus 로고
    • Influence of age and health behaviors on stroke risk: lessons from longitudinal studies
    • Kelly-Hayes M. Influence of age and health behaviors on stroke risk: lessons from longitudinal studies. J Am Geriatr Soc. 2010;58:S325-S328.
    • (2010) J Am Geriatr Soc , vol.58 , pp. S325-S328
    • Kelly-Hayes, M.1
  • 15
    • 84922381210 scopus 로고    scopus 로고
    • Heart disease and stroke statistics–2015 update: a report from the American Heart Association
    • Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics–2015 update: a report from the American Heart Association. Circulation. 2015;131:e29-e322.
    • (2015) Circulation , vol.131 , pp. e29-e322
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 16
    • 84892515796 scopus 로고    scopus 로고
    • Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010
    • Feigin VL, Forouzanfar MH, Krishnamurthi R, et al. Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet. 2014;383:245-254.
    • (2014) Lancet , vol.383 , pp. 245-254
    • Feigin, V.L.1    Forouzanfar, M.H.2    Krishnamurthi, R.3
  • 17
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
    • Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002;360:1903-1913.
    • (2002) Lancet , vol.360 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 18
    • 84930625821 scopus 로고    scopus 로고
    • Adherence of doctors to a clinical guideline for hypertension in Bojanala district, North-West Province, South Africa
    • Adedeji AR, Tumbo J, Govender I. Adherence of doctors to a clinical guideline for hypertension in Bojanala district, North-West Province, South Africa. Afr J Prim Health Care Fam Med. 2015;7:1–6.
    • (2015) Afr J Prim Health Care Fam Med , vol.7 , pp. 1-6
    • Adedeji, A.R.1    Tumbo, J.2    Govender, I.3
  • 19
    • 0026615154 scopus 로고
    • Social inequities in cardiovascular disease risk factors in East and West Germany
    • Helmert U, Mielck A, Classen E. Social inequities in cardiovascular disease risk factors in East and West Germany. Soc Sci Med. 1992;35:1283-1292.
    • (1992) Soc Sci Med , vol.35 , pp. 1283-1292
    • Helmert, U.1    Mielck, A.2    Classen, E.3
  • 20
    • 0343036301 scopus 로고    scopus 로고
    • The integration of two health systems: social stratification, work and health in East and West Germany
    • Luschen G, Niemann S, Apelt P. The integration of two health systems: social stratification, work and health in East and West Germany. Soc Sci Med. 1997;44:883-899.
    • (1997) Soc Sci Med , vol.44 , pp. 883-899
    • Luschen, G.1    Niemann, S.2    Apelt, P.3
  • 21
    • 84904270168 scopus 로고    scopus 로고
    • Treatment resistant hypertension – investigation and conservative management
    • Weber F, Anlauf M. Treatment resistant hypertension – investigation and conservative management. Dtsch Arztebl Int. 2014;111:425-431.
    • (2014) Dtsch Arztebl Int , vol.111 , pp. 425-431
    • Weber, F.1    Anlauf, M.2
  • 22
    • 84875223854 scopus 로고    scopus 로고
    • Resistant hypertension? Assessment of adherence by toxicological urine analysis
    • Jung O, Gechter JL, Wunder C, et al. Resistant hypertension? Assessment of adherence by toxicological urine analysis. J Hypertens. 2013;31:766-774.
    • (2013) J Hypertens , vol.31 , pp. 766-774
    • Jung, O.1    Gechter, J.L.2    Wunder, C.3
  • 23
    • 84914128800 scopus 로고    scopus 로고
    • A medication adherence and persistence comparison of hypertensive patients treated with single-, double- and triple-pill combination therapy
    • Xie L, Frech-Tamas F, Marrett E, Baser O. A medication adherence and persistence comparison of hypertensive patients treated with single-, double- and triple-pill combination therapy. Curr Med Res Opin. 2014;30:2415-2422.
    • (2014) Curr Med Res Opin , vol.30 , pp. 2415-2422
    • Xie, L.1    Frech-Tamas, F.2    Marrett, E.3    Baser, O.4
  • 24
    • 84928176162 scopus 로고    scopus 로고
    • Benefits of a fixed-dose combination of bisoprolol and amlodipine in the treatment of hypertension in daily practice: results of more than 4000 patients
    • Czarnecka D, Koch EM, Gottwald-Hostalek U. Benefits of a fixed-dose combination of bisoprolol and amlodipine in the treatment of hypertension in daily practice: results of more than 4000 patients. Curr Med Res Opin. 2015;31:875-881.
    • (2015) Curr Med Res Opin , vol.31 , pp. 875-881
    • Czarnecka, D.1    Koch, E.M.2    Gottwald-Hostalek, U.3
  • 25
    • 85019987565 scopus 로고    scopus 로고
    • Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment
    • Tung YC, Huang YC, Wu LS, Chang CJ, Chu PH. Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment. J Clin Hypertens (Greenwich). 2017;19:983-989.
    • (2017) J Clin Hypertens (Greenwich) , vol.19 , pp. 983-989
    • Tung, Y.C.1    Huang, Y.C.2    Wu, L.S.3    Chang, C.J.4    Chu, P.H.5
  • 26
    • 84865248639 scopus 로고    scopus 로고
    • Optimizing adherence in hypertension: a comparison of outcomes and costs using single tablet regimens vs individual component regimens
    • Belsey JD. Optimizing adherence in hypertension: a comparison of outcomes and costs using single tablet regimens vs individual component regimens. J Med Econ. 2012;15:897-905.
    • (2012) J Med Econ , vol.15 , pp. 897-905
    • Belsey, J.D.1
  • 27
    • 57649135136 scopus 로고    scopus 로고
    • Medication utilization patterns and hypertension-related expenditures among patients who were switched from fixed-dose to free-combination antihypertensive therapy
    • Hess G, Hill J, Lau H, Dastani H, Chaudhari P. Medication utilization patterns and hypertension-related expenditures among patients who were switched from fixed-dose to free-combination antihypertensive therapy. P T. 2008;33:652-666.
    • (2008) P T , vol.33 , pp. 652-666
    • Hess, G.1    Hill, J.2    Lau, H.3    Dastani, H.4    Chaudhari, P.5
  • 28
    • 77955640570 scopus 로고    scopus 로고
    • Evaluation of compliance and health care utilization in patients treated with single pill vs. free combination antihypertensives
    • Yang W, Chang J, Kahler KH, et al. Evaluation of compliance and health care utilization in patients treated with single pill vs. free combination antihypertensives. Curr Med Res Opin. 2010;26:2065-2076.
    • (2010) Curr Med Res Opin , vol.26 , pp. 2065-2076
    • Yang, W.1    Chang, J.2    Kahler, K.H.3
  • 29
    • 84878837718 scopus 로고    scopus 로고
    • Dynamic view on affordability of fixed-dose combination antihypertensive drug therapy
    • Hong SH, Wang J, Tang J. Dynamic view on affordability of fixed-dose combination antihypertensive drug therapy. Am J Hypertens. 2013;26:879-887.
    • (2013) Am J Hypertens , vol.26 , pp. 879-887
    • Hong, S.H.1    Wang, J.2    Tang, J.3
  • 30
    • 84890870566 scopus 로고    scopus 로고
    • Adherence and health care costs with single-pill fixed-dose combinations in hypertension management
    • Hilleman DE. Adherence and health care costs with single-pill fixed-dose combinations in hypertension management. J Manag Care Pharm. 2014;20:93-100.
    • (2014) J Manag Care Pharm , vol.20 , pp. 93-100
    • Hilleman, D.E.1
  • 31
    • 83055176357 scopus 로고    scopus 로고
    • Single-pill vs free-equivalent combination therapies for hypertension: a meta-analysis of health care costs and adherence
    • Sherrill B, Halpern M, Khan S, Zhang J, Panjabi S. Single-pill vs free-equivalent combination therapies for hypertension: a meta-analysis of health care costs and adherence. J Clin Hypertens (Greenwich). 2011;13:898-909.
    • (2011) J Clin Hypertens (Greenwich) , vol.13 , pp. 898-909
    • Sherrill, B.1    Halpern, M.2    Khan, S.3    Zhang, J.4    Panjabi, S.5
  • 32
    • 84921026181 scopus 로고    scopus 로고
    • Clinical outcomes and healthcare costs in hypertensive patients treated with a fixed-dose combination of amlodipine/valsartan
    • Tung Y-C, Lin Y-S, Wu L-S, Chang C-J, Chu P-H. Clinical outcomes and healthcare costs in hypertensive patients treated with a fixed-dose combination of amlodipine/valsartan. J Clin Hypertens (Greenwich). 2015;17:51-58.
    • (2015) J Clin Hypertens (Greenwich) , vol.17 , pp. 51-58
    • Tung, Y.-C.1    Lin, Y.-S.2    Wu, L.-S.3    Chang, C.-J.4    Chu, P.-H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.