Mismatch amplification mutation assay (MAMA): Application to the c-H-ras gene

Genome Research

Volumn 2, Issue 1, 1992, Pages 14-20

  Cha, Rita S ^a   Zarbl, Helmut ^a   Keohavong, Phouthone ^b   Thilly, William G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL; ARTICLE; CODON; FISCHER 344 RAT; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ONCOGENE RAS; POLYMERASE CHAIN REACTION; RAT; SENSITIVITY AND SPECIFICITY;

ALLELES; ANIMALS; BASE SEQUENCE; CODON; DNA MUTATIONAL ANALYSIS; GENES, RAS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED F344; SENSITIVITY AND SPECIFICITY;

EID: 85045497108     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.2.1.14     Document Type: Article

References (16)

1. Newton, C.R., A. Graham, L.E. Heptinstall, S.J. Powell, C. Summers, N. Kaisheker, J.C. Smith, and A.F. Markham. 1989. Analysis of any point mutation in DNA. The amplification refractory mutation system. Nucleic Acids Res 17: 2503-2516.
2. Nichols, W.C., J.J. Liepnieks, V.A. McKusick, and M.D. Benson. 1989. Direct sequencing of the gene for Maryland/ German familial amyloidotic polyneuropathy type II and genotyping by allele-specific enzymatic amplification. Genomics 5: 535-540.
3. Okayama, H., D.T. Curiel, M.L. Brantly, M.D. Holmes, and R.G. Crystal. 1989. Rapid, nonradioactive detection of mutations in the human genome by allele-specific amplification. J. Lab. Clin. Med. 114: 105-113.
4. Wu, D.Y., L. Ugozzoli, B.K. Pal, and R.B. Wallace. 1989. Allele-specific enzymatic amplification of β-globin genomic DNA for diagnosis of sickle cell anemia. Proc. Natl. Acad. Sci. 86: 2757-2760.
5. Ehlen, T. and L.Dubeau. 1989. Detection of ras point mutations by polymerase chain reaction using mutation-specific, inosine-containing oligonucleotide primers. Biochem. Biophys. Res. Commun. 160: 441-447.
6. Kan, Y.W. and A.M. Dozy. 1978. Antenatal diagnosis of sickle-cell anemia by DNA analysis of amniotic-fluid cells. Lancet: 910-912.
7. Verlaan-dc Vries, M., M.E. Bogaard, H. van de Elst, J.H. van Bloom, A.J. van der Eb, and J.L. Bos. 1986. A dot-blot screening procedure for mutated ras oncogenes using synthetic oligonucleotides. Gene 50: 313-320.
8. Sarkar, G., J. Cassady, C. Bottema, and S. Sommer. 1990. Characterization of polymerase chain reaction amplification of specific alleles. Anal Biochem. 186: 64-68.
9. Saiki, R.K., D.H. Gelfand, S. Stoffel, S.J. Scharf, R. Higuchi, G.T. Horn, K.B. Mullis, and H.A. Erlich. 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239: 487-491.
10. Kahn, S.M., W. Jiang, T.A. Culbertson, B. Weinstein, G.M. Williams, N. Tomita, and Z. Ronai. 1991. Rapid and sensitive nonradioactive detection of mutant K-ras genes via "enriched" PCR amplification. Oncogene 6: 1079-1083.
11. Kumar, R. and M. Barbacid. 1988. Oncogene detection at the single cell level. Oncogene 3: 647-651.
12. Kwok, S., D.E. Kellogg, N. McKinney, D. Spasic, L. Goda, and J.J. Sninsky. 1990. Effects of primer-template mismatches on the polymerase chain reaction: Human immunodeficiency virus type 1 model studies. Nucleic Acids Res. 18: 999-1005.
13. Kleppe, K., E. Ohtsuka, R. Kleppe, I. Molineux, and H.G. Khorana. 1971. Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases. J. Mol. Biol. 56: 341-361.
14. Saiki, R.K., S. Scharf, F. Faloona, K.B. Mullis, G.T. Horn, H.A. Erlich, and A. Arnheim. 1985. Enzymatic amplification of β-globin sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230: 1350-1354.
15. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular cloning: A laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
16. Fischer, S.G. and L.S. Lerman. 1983. DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: Correspondence with melting theory. Proc. Natl. Acad. Sci. 80: 1579-1583.