Scientific Opinion on the substantiation of a health claim related to vitamin D and risk of falling pursuant to Article 14 of Regulation (EC) No 1924/2006

EFSA Journal

Volumn 9, Issue 9, 2011, Pages

[No Author Info available]

Author keywords

bone fractures; calcium; falls; health claim; risk of falling; Vitamin D

Indexed keywords

EID: 85045447789     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2011.2382     Document Type: Article

References (26)

1. Annweiler C, Schott AM, Berrut G, Fantino B and Beauchet O, 2009. Vitamin D-related changes in physical performance: a systematic review. The journal of nutrition, health & aging, 13, 893–898.
2. Bischoff HA, Stähelin HB, Dick W, Akos R, Knecht M, Salis C, Nebiker M, Theiler R, Pfeifer M, Begerow B, Lew RA, and Conzelmann M, 2003. Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. Journal of Bone and Mineral Research, 18, 343–351.
3. Bischoff-Ferrari; HA, Dawson-Hughes; B, Willett WC, Staehelin HB, Bazemore MG, Zee RY and Wong JB, 2004. Effect of Vitamin D on falls: a meta-analysis. The Journal of the American Medical Association, 291, 1999–2006.
4. Bischoff-Ferrari; HA, Orav EJ and Dawson-Hughes; B, 2006. Effect of cholecalciferol plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trial. Archives of Internal Medicine, 166, 424–430.
5. Bischoff-Ferrari; HA, Dawson-Hughes; B, Staehelin HB, Orav JE, Stuck AE, Theiler R, Wong JB, Egli A, Kiel DP and Henschkowski J, 2009. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. British Medical Journal, 339, b3692.
6. Broe KE, Chen TC, Weinberg J, Bischoff-Ferrari; HA, Holick MF and Kiel DP, 2007. A higher dose of vitamin D reduces the risk of falls in nursing home residents: a randomized, multiple dose study. Journal of the American Geriatrics Society, 55, 234–239.
7. 3 chewing tablets and reduction of the risk of osteoporotic fractures by reducing bone loss. The EFSA Journal, 1180, 1–13.
8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), 2010a. Scientific Opinion in relation to the authorisation procedure for health claims on calcium and vitamin D and the reduction of the risk of osteoporotic fractures by reducing bone loss pursuant to Article 14 of Regulation (EC) No 1924/2006. EFSA Journal, 8(5):1609, 10 pp.
9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), 2010b. Scientific Opinion on the substantiation of health claims related to vitamin D and normal function of the immune system and inflammatory response (ID 154, 159), maintenance of normal muscle function (ID 155) and maintenance of normal cardiovascular function (ID 159) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal, 8(2):1468, 17 pp.
10. Faulkner KA, Cauley JA, Zmuda JM, Landsittel DP, Newman AB, Studenski SA, Redfern MS, Ensrud KE, Fink HA, Lane NE and Nevitt MC, 2006. Higher 1,25-dihydroxyvitamin D3 concentrations associated with lower fall rates in older community-dwelling women. Osteoporosis International, 17, 1318–1328.
11. Flicker L, Mead K, MacInnis RJ, Nowson C, Scherer S, Stein MS, Thomasx J, Hopper JL and Wark JD, 2003. Serum vitamin D and falls in older women in residential care in Australia. Journal of the American Geriatrics Society, 51, 1533–1538.
12. Flicker L, MacInnis RJ, Stein MS, Scherer SC, Mead KE, Nowson CA, Thomas J, Lowndes C, Hopper JL and Wark JD, 2005. Should older people in residential care receive vitamin D to prevent falls? Results of a randomized trial. Journal of the American Geriatrics Society, 53, 1881–1888.
13. Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG and Rowe BH, 2009. Interventions for preventing falls in older people living in the community. Cochrane Database of Systematic Reviews, 15, CD007146.
14. Graafmans WC, Ooms ME, Hofstee HA, Bezemer PD, Bouter LM and Lipps P, 1996. Falls in the Elderly: A prospective study of risk factors and risk profiles. American Journal of Epidemiology, 143, 1129–1136.
15. Horlings C, Van Engelen B, Allum J and Bloem B, 2008. A weak balance: the contribution of muscle weakness to postural instability and falls. Neurology, 4, 504–515.
16. IoM (Institute of Medicine), 2010. Dietary Reference Intakes for Calcium and Vitamin D. Ross AC, Taylor CL, Yaktine AL and Del Valle HB. The National Academies Press, Washington, D.C.
17. Jackson C, Gaugris S, Sen SS and Hosking D, 2007. The effect of cholecalciferol (vitamin D3) on the risk of fall and fracture: a meta-analysis. QJM: Monthly Journal of the Association of Physicians, 100, 185–192.
18. Latham NK, Anderson CS and Reid IR, 2003. Effects of vitamin D supplementation on strength, physical performance, and falls in older persons: a systematic review. Journal of the American Geriatrics Society, 51, 1219–1226.
19. Lloyd BD, Williamson DA, Singh NA, Hansen RD, Diamond TH, Finnegan TP, Allen BJ, Grady JN, Stavrinos TM, Smith EUR, Diwqan AD and Fiatorone Singh MA, 2009. Recurrent and injurious falls in the year following hip fracture: a prospective study of incidence and risk factors from the sarcopenia and hip fracture study. Journal of Gerontology, 64A, 599–609.
20. Pfeifer M, Begerow B, Minne HW, Abrams C, Nachtigall D and Hansen C, 2000. Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyroidsm in elderly women. Journal of Bone and Mineral Research, 15, 1113–1118.
21. Pfeifer M, Begerow B, Minne HW, Suppan K, Fahrleitner-Pammer; A and Dobnig H, 2009. Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals. Osteoporosis International, 20, 315–322.
22. Pramyothin P, Techasurungkul S, Lin J, Wang H, Shah A, Ross PD, Puapong R and Wasnich RD, 2009. Vitamin D status and falls, frailty, and fractures among postmenopausal Japanese women living in Hawaii. Osteoporosis International, 20, 1955–1962.
23. Prince RL, Austin N, Devine A, Dick IM, Bruce D and Zhu K, 2008. Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women. Archives of Internal Medicine, 168, 103–108.
24. Skelton D and Todd C, 2004, online. What are the main risk factors for falls amongst older people and what are the most effective interventions to prevent these falls. WHO, Europe, Health Evidence Network Report. Available from: www.euro.who.int/docuemnt/E82552.pdf.
25. Snijder MB, van Schoor NM, Pluijm SM, van Dam RM, Visser M and Lips P, 2006. Vitamin D status in relation to one-year risk of recurrent falling in older men and women. Journal of Clinical Endocrinology & Metabolism, 91, 2980–2985.
26. Tinetti M, Speechley M and Ginter S, 1988. Risk factors for falls among elderly persons living in the community. The New England Journal of Medicine, 319, 1701–1707.