Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, placebo-controlled study

Journal of Dairy Science

Volumn 101, Issue 6, 2018, Pages 4830-4841

  Gomi, A ^a   Yamaji, K ^a   Watanabe, O ^b   Yoshioka, M ^b   Miyazaki, K ^a   Iwama, Y ^c   Urita, Y ^d  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

^b Faculty of Research and Development   (Japan)

^c Nihonbashi Cardiology Clinic   (Japan)

^d TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

functional dyspepsia; gastrointestinal symptom; healthy adult; probiotics

Indexed keywords

PROBIOTIC AGENT;

ADULT; ANALYSIS; ANIMAL; BIFIDOBACTERIUM BIFIDUM; CONTROLLED STUDY; DIET THERAPY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; FERMENTATION; FERMENTED MILK PRODUCT; GASTROINTESTINAL DISEASE; HUMAN; JAPAN; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; MILK; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; STOMACH EMPTYING; YOUNG ADULT;

ADULT; ANIMALS; BIFIDOBACTERIUM BIFIDUM; CULTURED MILK PRODUCTS; DOUBLE-BLIND METHOD; FEMALE; FERMENTATION; GASTRIC EMPTYING; GASTROINTESTINAL DISEASES; HUMANS; JAPAN; MALE; MIDDLE AGED; MILK; PROBIOTICS; PROSPECTIVE STUDIES; QUALITY OF LIFE; YOUNG ADULT;

EID: 85044257291     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2017-13803     Document Type: Article

References (22)

1. FAO/WHO, Joint FAO/WHO Working Group: Guidelines for the Evaluation of Probiotics in Food. London, ON, Canada http://www.who.int/foodsafety/fs_management/en/probiotic_guidelines.pdf, 2002. (Accessed 2 March 2018)
2. Fukuhara, S., Suzukamo, Y., Manual of SF-36v2; Japanese version. 2004, Institute for Health Outcomes & Process Evaluation Research, Kyoto, Japan (in Japanese).
3. Gomi, A., Harima-Mizusawa, N., Shibahara-Sone, H., Kano, M., Miyazaki, K., Ishikawa, F., Effect of Bifidobacterium bifidum BF-1 on gastric protection and mucin production in an acute gastric injury rat model. J. Dairy Sci. 96 (2013), 832–837 23200466.
4. Gomi, A., Iino, T., Nonaka, C., Miyazaki, K., Ishikawa, F., Health benefits of fermented milk containing Bifidobacterium bifidum YIT 10347 on gastric symptoms in adults. J. Dairy Sci. 98 (2015), 2277–2283 25648808.
5. Heuchert, J.P., McNair, D.M., Profile of Mood States. second edition, 2012, Multi-Health Systems, North Tonawanda, NY (POMS 2®).
6. Hongo, M., Fukuhara, T., Green, J., QOL in digestive region. Diagn. Treat. 87 (1999), 731–736 (in Japanese).
7. Kusano, M., [Questionnaires for GERD, QUEST and F scale]. Nihon Rinsho 65 (2007), 846–851 (in Japanese) 17511223.
8. Kusano, M., Hosaka, H., Kawada, A., Kuribayashi, S., Shimoyama, Y., Kawamura, O., Moki, F., Development and evaluation of a modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease to distinguish functional dyspepsia from non-erosive reflux disease. J. Gastroenterol. Hepatol. 27 (2012), 1187–1191 22414314.
9. Kusano, M., Shimoyama, Y., Sugimoto, S., Kawamura, O., Maeda, M., Minashi, K., Kuribayashi, S., Higuchi, T., Zai, H., Ino, K., Horikoshi, T., Sugiyama, T., Toki, M., Ohwada, T., Mori, M., Development and evaluation of FSSG: Frequency scale for the symptoms of GERD. J. Gastroenterol. 39 (2004), 888–891 15565409.
10. Kusunoki, H., Kusaka, M., Kido, S., Yamauchi, R., Fujimura, Y., Watanabe, Y., Kobori, M., Miwa, H., Tomita, T., Kin, Y., Hori, K., Tano, N., Sugimoto, K., Nakamura, Y., Fujimoto, K., Oza, N., Matsunobu, A., Ono, N., Fuyuno, S., Kinoshita, Y., Adachi, K., Yuki, M., Fujisawa, T., Haruma, K., Comparison of the effects of omeprazole and famotidine in treatment of upper abdominal symptoms in patients with reflux esophagitis. J. Gastroenterol. 44 (2009), 261–270 19280112.
11. Manabe, N., Haruma, K., Kamada, T., Kusunoki, H., Inoue, K., Murao, T., Imamura, H., Matsumoto, H., Tarumi, K., Shiotani, A., Hata, J., Changes of upper gastrointestinal symptoms and endoscopic findings in Japan over 25 years. Intern. Med. 50 (2011), 1357–1363 21720053.
12. McNair, D.M., Lorr, M., Droppleman, L.F., Profile of Mood States. 1971, Educational and Industrial Testing Service, San Diego, CA.
13. Miki, K., Urita, Y., Ishikawa, F., Iino, T., Shibahara-Sone, H., Akahoshi, R., Mizusawa, S., Nose, A., Nozaki, D., Hirano, K., Nonaka, C., Yokokura, T., Effect of Bifidobacterium bifidum fermented milk on Helicobacter pylori and serum pepsinogen levels in humans. J. Dairy Sci. 90 (2007), 2630–2640 17517703.
14. Sanaka, M., Urita, Y., Yamamoto, T., Shirai, T., Kimura, S., Aoyagi, H., Kuyama, Y., Right recumbent position on gastric emptying of water evidenced by (13)C breath testing. World J. Gastroenterol. 19 (2013), 362–365 23372358.
15. Shibahara-Sone, H., Gomi, A., Iino, T., Kano, M., Nonaka, C., Watanabe, O., Miyazaki, K., Ohkusa, T., Living cells of probiotic Bifidobacterium bifidum YIT 10347 detected on gastric mucosa in humans. Benef. Microbes 7 (2016), 319–326 26925600.
16. Shirasawa, Y., Shibahara-Sone, H., Iino, T., Ishikawa, F., Bifidobacterium bifidum BF-1 suppresses Helicobacter pylori-induced genes in human epithelial cells. J. Dairy Sci. 93 (2010), 4526–4534 20854986.
17. Stanghellini, V., Three-month prevalence rates of gastrointestinal symptoms and the influence of demographic factors: Results from the Domestic/International Gastroenterology Surveillance Study (DIGEST). Scand. J. Gastroenterol. Suppl. 231 (1999), 20–28 10565620.
18. Stanghellini, V., Rome IV—Gastroduodenal disorders. Gastroenterology 150 (2016), 1380–1392 10.1053/j.gastro.2016.02.011 27144626.
19. Svedlund, J., Sjodin, I., Dotevall, G., GSRS—A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig. Dis. Sci. 33 (1988), 129–134 3123181.
20. Tominaga, K., Kato, M., Takeda, H., Shimoyama, Y., Umegaki, E., Iwakiri, R., Furuta, K., Sakurai, K., Odaka, T., Kusunoki, H., Nagahara, A., Iwakiri, K., Furuta, T., Murakami, K., Miwa, H., Kinoshita, Y., Haruma, K., Takahashi, S., Watanabe, S., Higuchi, K., Kusano, M., Fujimoto, K., Arakawa, T., Pride, G., Study Group, A randomized, placebo-controlled, double-blind clinical trial of rikkunshito for patients with non-erosive reflux disease refractory to proton-pump inhibitor: The G-PRIDE study. J. Gastroenterol. 49 (2014), 1392–1405.
21. Urita, Y., Goto, M., Watanabe, T., Matsuzaki, M., Gomi, A., Kano, M., Miyazaki, K., Kaneko, H., Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal disorders. Biosci. Microbiota Food Health 34 (2015), 37–44 25918671.
22. Yokoyama, K., Araki, S., Kawakami, N., Tkakeshita, T., [Production of the Japanese edition of Profile of Mood States (POMS): Assessment of reliability and validity.]. Nihon Koshu Eisei Zasshi 37 (1990), 913–918 (in Japanese). 2132363.