Burden of severe RSV disease among immunocompromised children and adults: A 10 year retrospective study

BMC Infectious Diseases

Volumn 18, Issue 1, 2018, Pages

  Chatzis, Olga ^a   Darbre, Stephanie ^b   Pasquier, Jérôme ^c   Meylan, Pascal ^d   Manuel, Oriol ^b   Aubert, John David ^b   Beck Popovic, Maja ^b   Masouridi Levrat, Stavroula ^e   Ansari, Marc ^a   Kaiser, Laurent ^a,e   Posfay Barbe, Klara M ^a   Asner, Sandra A ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

^e GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PALIVIZUMAB; RIBAVIRIN;

ADULT; AGED; ARTICLE; BACTEREMIA; BACTERIAL PNEUMONIA; CHILD; CLINICAL OUTCOME; COHORT ANALYSIS; DISEASE BURDEN; DISEASE SEVERITY; FEMALE; HEMATOPOIETIC STEM CELL; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; IMMUNOCOMPROMISED PATIENT; INTENSIVE CARE UNIT; LENGTH OF STAY; LOWER RESPIRATORY TRACT INFECTION; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORTALITY RATE; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RETROSPECTIVE STUDY; RISK FACTOR; SOLID MALIGNANT NEOPLASM; VASCULITIS; ADOLESCENT; CLINICAL TRIAL; INFANT; MULTICENTER STUDY; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTION; STATISTICAL MODEL; VIROLOGY; VIRUS PNEUMONIA; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; COINFECTION; FEMALE; HOSPITALIZATION; HUMANS; IMMUNOCOMPROMISED HOST; INFANT; LOGISTIC MODELS; MALE; PNEUMONIA, VIRAL; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 85043376034     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-018-3002-3     Document Type: Article

References (33)

1. Resch B, Manzoni P, Lanari M. Severe respiratory syncytial virus (RSV) infection in infants with neuromuscular diseases and immune deficiency syndromes. Paediatr Respir Rev. 2009;10(3):148-53.
2. Hall CB, et al. Respiratory syncytial viral infection in children with compromised immune function. N Engl J Med. 1986;315(2):77-81.
3. Hall CB. Respiratory syncytial virus and parainfluenza virus. N Engl J Med. 2001;344(25):1917-28.
4. Falsey AR, et al. Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med. 2005;352(17):1749-59.
5. Hall CB, Long CE, Schnabel KC. Respiratory syncytial virus infections in previously healthy working adults. Clin Infect Dis. 2001;33(6):792-6.
6. Volling C, et al. Respiratory syncytial virus infection-associated hospitalization in adults: a retrospective cohort study. BMC Infect Dis. 2014;14:665.
7. Lanari M, et al. Respiratory syncytial virus infections in infants affected by primary immunodeficiency. J Immunol Res. 2014;2014:850831.
8. Aebi CEA. Consensus concernant la prévention des infections par le virus respiratoire syncitial (VRS) avec l'anticorps humanisé monoclonal palivizumab (Synagis). Paediatrica. 2004;15(6):17-9.
9. Khanna N, et al. Respiratory syncytial virus infection in patients with hematological diseases: single-center study and review of the literature. Clin Infect Dis. 2008;46(3):402-12.
10. Ljungman P, et al. Respiratory virus infections after stem cell transplantation: a prospective study from the infectious diseases working Party of the European Group for blood and marrow transplantation. Bone Marrow Transplant. 2001;28(5):479-84.
11. Kim YJ, et al. Respiratory syncytial virus in hematopoietic cell transplant recipients: factors determining progression to lower respiratory tract disease. J Infect Dis. 2014;209(8):1195-204.
12. Shah DP, et al. Immunodeficiency scoring index to predict poor outcomes in hematopoietic cell transplant recipients with RSV infections. Blood. 2014;123(21):3263-8.
13. Jonckheere S, et al. Multicenter evaluation of BD Veritor system and RSV K-SeT for rapid detection of respiratory syncytial virus in a diagnostic laboratory setting. Diagn Microbiol Infect Dis. 2015;83(1):37-40.
14. Franz A, et al. Correlation of viral load of respiratory pathogens and co-infections with disease severity in children hospitalized for lower respiratory tract infection. J Clin Virol. 2010;48(4):239-45.
15. Regamey N, et al. Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study. Pediatr Infect Dis J. 2008;27(2):100-5.
16. Salez N, et al. Prospective and retrospective evaluation of the Cepheid Xpert(R) flu/RSV XC assay for rapid detection of influenza a, influenza B, and respiratory syncytial virus. Diagn Microbiol Infect Dis. 2015;81(4):256-8.
17. Mermel LA, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009, 49(1):1-45.
18. Martin ET, et al. Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children. Influenza Other Respir Viruses. 2012;6(1):71-7.
19. Kamigaki T, et al. Estimates of influenza and respiratory syncytial virus incidences with fraction modeling approach in Baguio City, the Philippines, 2012-2014. Influenza Other Respir Viruses. 2017;11(4):311-8.
20. Emukule GO, et al. Estimating influenza and respiratory syncytial virus-associated mortality in western Kenya using health and demographic surveillance system data, 2007-2013. PLoS One. 2017;12(7):e0180890.
21. Duppenthaler A, et al. Low incidence of respiratory syncytial virus hospitalisations in haemodynamically significant congenital heart disease. Arch Dis Child. 2004;89(10):961-5.
22. Pastula ST, et al. Hospitalizations for Respiratory Syncytial Virus Among Adults in the United States, 1997-2012. Open Forum Infect Dis. 2017;4(1):ofw270.
23. Modjarrad K, et al. WHO consultation on respiratory syncytial virus vaccine development report from a World Health Organization meeting held on 23-24 march 2015. Vaccine. 2016;34(2):190-7.
24. Hament JM, et al. Direct binding of respiratory syncytial virus to pneumococci: a phenomenon that enhances both pneumococcal adherence to human epithelial cells and pneumococcal invasiveness in a murine model. Pediatr Res. 2005;58(6):1198-203.
25. Boeckh M, et al. Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients. Clin Infect Dis. 2007;44(2):245-9.
26. Asner SA, et al. Is virus coinfection a predictor of severity in children with viral respiratory infections? Clin Microbiol Infect. 2015;21(3):264 e1-6.
27. Top FH Jr, Connor EM, Carlin DA. Prophylaxis against respiratory syncytial virus in premature infants. IMpact-RSV Study Group. Lancet. 2000;355(9208):1014.
28. Asner SA, et al. Clinical disease severity of respiratory viral co-infection versus single viral infection: a systematic review and meta-analysis. PLoS One. 2014;9(6):e99392.
29. Asner S, et al. Risk factors and outcomes for respiratory syncytial virus-related infections in immunocompromised children. Pediatr Infect Dis J. 2013;32(10):1073-6.
30. Navas L, et al. Improved outcome of respiratory syncytial virus infection in a high-risk hospitalized population of Canadian children. Pediatric Investigators Collaborative Network on Infections in Canada. J Pediatr. 1992;121(3):348-54.
31. Chu HY, et al. Clinical outcomes in outpatient respiratory syncytial virus infection in immunocompromised children. Influenza Other Respir Viruses. 2016;10(3):205-10.
32. Santos RP, et al. The use of intravenous palivizumab for treatment of persistent RSV infection in children with leukemia. Pediatrics. 2012;130(6):e1695-9.
33. Shachor-Meyouhas Y, et al. Detection, control, and management of a respiratory syncytial virus outbreak in a pediatric hematology-oncology department. J Pediatr Hematol Oncol. 2013;35(2-5 years2):124-8.