Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson's disease?

Acta neuropathologica communications

Volumn 5, Issue 1, 2017, Pages 71-

  Matsumoto, Junichi ^a   Stewart, Tessandra ^a   Sheng, Lifu ^a   Li, Na ^b   Bullock, Kristin ^c   Song, Ning ^a   Shi, Min ^a   Banks, William A ^a,c   Zhang, Jing ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

Author keywords

Alpha synuclein; Blood brain barrier; Extracellular vesicles; Inflammation; Microglia; Parkinson s disease

Indexed keywords

ALPHA SYNUCLEIN; LIPOPOLYSACCHARIDE; SNCA PROTEIN, HUMAN;

ANIMAL; ANIMAL MODEL; BLOOD BRAIN BARRIER; CAPILLARY PERMEABILITY; CELL CULTURE TECHNIQUE; CELL LINE; DISEASE EXACERBATION; ERYTHROCYTE; EXOSOME; MALE; METABOLISM; MICROGLIA; MOUSE; PARKINSON DISEASE; PATHOLOGY; PHYSIOLOGY; TRANSCYTOSIS;

ALPHA-SYNUCLEIN; ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CELL CULTURE TECHNIQUES; CELL LINE; DISEASE PROGRESSION; ERYTHROCYTES; EXTRACELLULAR VESICLES; LIPOPOLYSACCHARIDES; MALE; MICE; MICROGLIA; MODELS, ANIMAL; PARKINSON DISEASE; TRANSCYTOSIS;

EID: 85042660723     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-017-0470-4     Document Type: Article

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