Adverse prognosis associated with asymmetric myocardial thickening in aortic stenosis

European Heart Journal Cardiovascular Imaging

Volumn 19, Issue 3, 2018, Pages 347-356

  Kwiecinski, Jacek ^a,b   Chin, Calvin W L ^a,c   Everett, Russell J ^a   White, Audrey C ^a   Semple, Scott ^a,d   Yeung, Emily ^a   Jenkins, William J ^a   Shah, Anoop S V ^a   Koo, Maria ^a   Mirsadraee, Saeed ^a   Lang, Chim C ^e   Mills, Nicholas ^a   Prasad, Sanjay K ^f   Jansen, Maurits A ^a   Japp, Alan G ^a   Newby, David E ^a   Dweck, Marc R ^a,g  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^c DEPARTMENT OF CARDIOLOGY   (Singapore)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF DUNDEE   (United Kingdom)

^f ROYAL BROMPTON HOSPITAL   (United Kingdom)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

aortic stenosis; asymmetric wall thickening; echocardiography; hypertrophy; magnetic resonance; troponin

Indexed keywords

GADOBUTROL; GADOLINIUM; TROPONIN I;

AGED; AORTIC STENOSIS; ARTERIAL WALL THICKENING; ARTICLE; CARDIAC MUSCLE; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL OUTCOME; COHORT ANALYSIS; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FEMALE; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; ADAPTATION; AORTIC VALVE STENOSIS; CARDIOMEGALY; CASE CONTROL STUDY; CINE MAGNETIC RESONANCE IMAGING; CONFIDENCE INTERVAL; DIAGNOSTIC IMAGING; MIDDLE AGED; MORTALITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; REFERENCE VALUE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE; TRANSCATHETER AORTIC VALVE IMPLANTATION; TREATMENT OUTCOME;

ADAPTATION, PHYSIOLOGICAL; AGED; AORTIC VALVE STENOSIS; CARDIOMEGALY; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; ECHOCARDIOGRAPHY; FEMALE; GADOLINIUM; HUMANS; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MYOCARDIUM; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; REFERENCE VALUES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE; TRANSCATHETER AORTIC VALVE REPLACEMENT; TREATMENT OUTCOME;

EID: 85042593594     PISSN: 20472404     EISSN: 20472412     Source Type: Journal    
DOI: 10.1093/ehjci/jex052     Document Type: Article

References (15)

1. Carabello BA. Introduction to aortic stenosis. Circ Res 2013; 113: 179-85.
2. Dweck MR, Boon NA, Newby DE. Calcific aortic stenosis a disease of the valve and the myocardium. J Am Coll Cardiol 2012; 60: 1854-63.
3. Chin CWL, Vassiliou V, Jenkins WSA, Prasad SK, Newby DE, Dweck MR. Markers of left ventricular decompensation in aortic stenosis. Expert Rev Cardiovasc Ther 2014; 12: 901-12.
4. Maron BJ. Hypertrophic cardiomyopathy-a systematic review. JAMA 2002; 287: 1308-20.
5. Tuseth N, Cramariuc D, Rieck AE, Wachtell K, Gerdts E. Asymmetric septal hypertrophy-a marker of hypertension in aortic stenosis (a SEAS substudy). Blood Press 2010; 19: 140-4.
6. Dweck MR, Joshi S, Murigu T, Gulati A, Alpendurada F, Jabbour A et al. Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2012; 14. http://jcmr-online. biomedcentral. com/about.
7. Panza JA, Maron BJ. Valvular aortic stenosis and asymmetric septal hypertrophy-diagnostic considerations and clinical and therapeutic implications. Eur Heart J 1988; 9: 71-6.
8. Maron BJ, Clark CE, Henry WL, Fukuda T, Edwards JE, Mathews EC et al. Prevalence and characteristics of disproportionate ventricular septal thickening in patients with acquired or congenital heart diseases-echocardiographic and morphological findings. Circulation 1977; 55: 489-96.
9. Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2006; 8: 417-26.
10. Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP et al. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. Eur J Echocardiogr 2009; 10: 1-25.
11. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2015; 16: 233-71.
12. Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in human left-ventricle. J Clin Invest 1975; 56: 56-64.
13. Heng MK, Janz RF, Jobin J. Estimation of regional stress in the left-ventricular septum and free wall-as echocardiographic study suggesting a mechanism for asymmetric septal hypertrophy. Am Heart J 1985; 110: 84-90.
14. Hess OM, Schneider J, Turina M, Carroll JD, Rothlin M, Krayenbuehl HP. Asymmetric septal hypertrophy in patients with aortic stenosis-an adaptive mechanism or a coexistence of hypertophic cardiomyopathy. J Am Coll Cardiol 1983; 1: 783-9.
15. Chin CWL, Shah ASV, McAllister DA, Cowell SJ, Alam S, Langrish JP et al. Highsensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis. Eur Heart J 2014; 35: 2312-21.