Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: A substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial

Canadian Journal of Kidney Health and Disease

Volumn 5, Issue , 2018, Pages

  Garg, Amit X ^a   Shehata, Nadine ^b   McGuinness, Shay ^c   Whitlock, Richard ^d   Fergusson, Dean ^e   Wald, Ron ^f   Parikh, Chirag ^g   Bagshaw, Sean M ^h   Khanykin, Boris ⁱ   Gregory, Alex ^j   Syed, Summer ^k   Hare, Gregory M T ^f   Cuerden, Meaghan S ^a   Thorpe, Kevin E ^b,l   Hall, Judith ^f   Verma, Subodh ^f   Roshanov, Pavel S ^k   Sontrop, Jessica M ^a   Mazer, C David ^f  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Cardiothoracic and Vascular Intensive Care Unit   (New Zealand)

^d MCMASTER UNIVERSITY   (Canada)

^e OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^f ST MICHAEL'S HOSPITAL   (Canada)

^g YALE UNIVERSITY   (United States)

^h UNIVERSITY OF ALBERTA   (Canada)

ⁱ Rigshospitalet   (Denmark)

^j UNIVERSITY OF CALGARY   (Canada)

^k MCMASTER UNIVERSITY   (Canada)

^l ST MICHAEL'S HOSPITAL   (Canada)

more..

Author keywords

Acute kidney injury; Anemia; Cardiac surgery; Cardiopulmonary bypass; Transfusion

Indexed keywords

ACUTE KIDNEY FAILURE; ADULT; ANEMIA; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL PROTOCOL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ERYTHROCYTE TRANSFUSION; ESTIMATED GLOMERULAR FILTRATION RATE; EUROSCORE; HEART SURGERY; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTOCOL COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; RISK;

EID: 85041617821     PISSN: None     EISSN: 20543581     Source Type: Journal    
DOI: 10.1177/2054358117749532     Document Type: Article

References (38)

1. Chiavetta JA, Herst R, Freedman J, Axcell TJ, Wall AJ, van Rooy SC. A survey of red cell use in 45 hospitals in central Ontario, Canada. Transfusion. 1996;36:699-706.
2. Josephson CD, Glynn SA, Kleinman SH, Blajchman MA; State-of-the Science Symposium Transfusion Medicine Committee. A multidisciplinary “think tank”: the top 10 clinical trial opportunities in transfusion medicine from the National Heart, Lung, and Blood Institute-sponsored 2009 state-of-the-science symposium. Transfusion. 2011;51:828-841.
3. Reeves BC, Murphy GJ. Increased mortality, morbidity, and cost associated with red blood cell transfusion after cardiac surgery. Curr Opin Cardiol. 2008;23:607-612.
4. Carson JL, Carless PA, Hebert PC, et al. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2012;CD002042.
5. Karkouti K, Beattie WS, Wijeysundera DN, et al. Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in adult cardiac surgery. J Thorac Cardiovasc Surg. 2005;129:391-400.
6. Carson JL, Stanworth SJ, Roubinian N, et al. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2016;10:CD002042.
7. Murphy GJ, Pike K, Rogers CA, et al. Liberal or restrictive transfusion after cardiac surgery. N Engl J Med. 2015;372 997-1008.
8. Curley GF, Shehata N, Mazer CD, Hare GM, Friedrich JO. Transfusion triggers for guiding RBC transfusion for cardiovascular surgery: a systematic review and meta-analysis. Crit Care Med. 2014;42:2611-2624.
9. Hajjar LA, Vincent J-L, Galas FRBG, et al. Transfusion requirements after cardiac surgery. JAMA. 2010;304:1559-1567.
10. Shehata N, Mazer CD, Thorpe KE. Blood transfusion and cardiac surgery. JAMA. 2011;305:357-358.
11. Thiele RH, Isbell JM, Rosner MH. AKI associated with cardiac surgery. Clin J Am Soc Nephrol. 2015;10:500-514.
12. Kiers HD, van den Boogaard M, Schoenmakers MCJ, van der Hoeven JG, van Swieten HA, Heemskerk S, Pickkers P. Comparison and clinical suitability of eight prediction models for cardiac surgery-related acute kidney injury. Nephrol Dial Transplant. 2013;28:345-351.
13. Rosner MH, Okusa MD. Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol. 2006;1:19-32.
14. Ricci Z, Cruz D, Ronco C. The RIFLE criteria and mortality in acute kidney injury: a systematic review. Kidney Int. 2008;73:538-546.
15. Dasta JF, Kane-Gill SL, Durtschi AJ, Pathak DS, Kellum JA. Costs and outcomes of acute kidney injury (AKI) following cardiac surgery. Nephrol Dial Transplant. 2008;23:1970-1974.
16. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16:3365-3370.
17. Ishani A, Nelson D, Clothier B, et al. The magnitude of acute serum creatinine increase after cardiac surgery and the risk of chronic kidney disease, progression of kidney disease, and death. Arch Intern Med. 2011;171:226-233.
18. ClinicalTrials.gov. Transfusion Requirements in Cardiac Surgery III (TRICS-III) (NCT02042898).https://clinicaltrials.gov/ct2/show/NCT02042898. Accessed December 7, 2017.
19. Garg AX, Devereaux PJ, Yusuf S, et al. Kidney function after off-pump or on-pump coronary artery bypass graft surgery: a randomized clinical trial. JAMA. 2014;311:2191-2198.
20. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2:1-138.
21. Parikh CR, Coca SG, Thiessen-Philbrook H, et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery. J Am Soc Nephrol. 2011;22:1748-1757.
22. Jones B, Jarvis P, Lewis JA, Ebbutt AF. Trials to assess equivalence: the importance of rigorous methods. BMJ. 1996;313: 36-39.
23. Kaul S, Diamond GA. Good enough: a primer on the analysis and interpretation of noninferiority trials. Ann Intern Med. 2006;145:62-69.
24. Little RJ, D’Agostino R, Cohen ML, et al. The prevention and treatment of missing data in clinical trials. N Engl J Med. 2012;367:1355-1360.
25. Carpenter JR, Kenward MG. Missing data in randomised controlled trials—a practical guide. 2007. https://pdfs.semanticscholar.org/e9c4/6359114e7eb6fd17d3ff93fec7ce54479ef5. pdf. Accessed February 7, 2017.
26. Garg AX, Kurz A, Sessler DI, et al. Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial. JAMA. 2014;312:2254-2264.
27. Wijeysundera DN, Karkouti K, Dupuis J-Y, et al. Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery. JAMA. 2007;297:1801-1809.
28. Palomba H, de Castro I, Neto ALC, Lage S, Yu L. Acute kidney injury prediction following elective cardiac surgery: AKICS Score. Kidney Int. 2007;72:624-631.
29. Hsu CY, Ordoñez JD, Chertow GM, Fan D, McCulloch CE, Go AS. The risk of acute renal failure in patients with chronic kidney disease. Kidney Int. 2008;74:101-107.
30. Chawla LS, Kimmel PL. Acute kidney injury and chronic kidney disease: an integrated clinical syndrome. Kidney Int. 2012;82:516-524.
31. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296-1305.
32. Tonelli M, Wiebe N, Culleton B, et al. Chronic kidney disease and mortality risk: a systematic review. J Am Soc Nephrol. 2006;17:2034-2047.
33. Thakar CV, Arrigain S, Worley S, Yared JP, Paganini EP. A clinical score to predict acute renal failure after cardiac surgery. J Am Soc Nephrol. 2005;16:162-168.
34. Kolli H, Rajagopalam S, Patel N, et al. Mild acute kidney injury is associated with increased mortality after cardiac surgery in patients with eGFR < 60 mL/min/1.73 m(2). Ren Fail. 2010;32:1066-1072.
35. Alkhunaizi AM, Shah SSA, Wesslen US, Al Sadah ZA, Antony A. Acute kidney injury after cardiac surgery in eastern Saudi Arabia. East Mediterr Health J. 2011;17:495-500.
36. Austin PC. Absolute risk reductions, relative risks, relative risk reductions, and numbers needed to treat can be obtained from a logistic regression model. J Clin Epidemiol. 2010;63:2-6.
37. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P; Acute Dialysis Quality Initiative Workgroup. Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8: R204-R112.
38. Mehta RL, Kellum JA, Shah SV, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11:31.