Association between Non-Iron-Deficient Anemia and Insomnia Symptoms in Community-Dwelling Older Adults: The Baltimore Longitudinal Study of Aging

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 73, Issue 3, 2018, Pages 380-385

  Chen Edinboro, Lenis P ^a   Murray Kolb, Laura E ^b   Simonsick, Eleanor M ^c   Ferrucci, Luigi ^c   Allen, Richard ^d   Payne, Martha E ^e   Spira, Adam P ^f,g  

^a UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f JOHNS HOPKINS UNIVERSITY   (United States)

^g JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

hemoglobin; iron; sleep

Indexed keywords

AGED; ANEMIA; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; INDEPENDENT LIVING; INSOMNIA; LONGITUDINAL STUDY; MALE; MARYLAND; PREVALENCE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANEMIA; BALTIMORE; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INDEPENDENT LIVING; LONGITUDINAL STUDIES; MALE; PREVALENCE; SLEEP INITIATION AND MAINTENANCE DISORDERS;

EID: 85041346128     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glw332     Document Type: Article

References (39)

1. Culleton BF, Manns BJ, Zhang J, Tonelli M, Klarenbach S, Hemmelgarn BR. Impact of anemia on hospitalization and mortality in older adults. Blood. 2006;107:3841-3846.
2. Deal JA, Carlson MC, Xue QL, Fried LP, Chaves PH. Anemia and 9-year domain-specific cognitive decline in community-dwelling older women: the Women's Health and Aging Study II. J Am Geriatr Soc. 2009;57:1604-1611.
3. Ancoli-Israel S, Cooke JR. Prevalence and comorbidity of insomnia and effect on functioning in elderly populations. J Am Geriatr Soc. 2005;53:S264-S271.
4. Baglioni C, Battagliese G, Feige B, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011;135:10-19.
5. Spira AP, Chen-Edinboro LP, Wu MN, Yaffe K. Impact of sleep on the risk of cognitive decline and dementia. Curr Opin Psychiatry. 2014;27:478-483.
6. Kordas K, Siegel EH, Olney DK, Katz J, Tielsch JM, Chwaya HM, et al. Maternal reports of sleep in 6-18 month-old infants from Nepal and Zanzibar: association with iron deficiency anemia and stunting. Early Hum Dev. 2008;84:389-398.
7. Peirano P, Algarin C, Garrido M, Algarin D, Lozoff B. Iron-deficiency anemia is associated with altered characteristics of sleep spindles in NREM sleep in infancy. Neurochem Res. 2007;32:1665-1672.
8. Kordas K, Siegel EH, Olney DK, et al. The effects of iron and/or zinc supplementation on maternal reports of sleep in infants from Nepal and Zanzibar. J Dev Behav Pediatr. 2009;30:131-139.
9. Peirano PD, Algarin CR, Chamorro RA, et al. Sleep alterations and iron deficiency anemia in infancy. Sleep Med. 2010;11:637-642.
10. Peirano PD, Algarin CR, Garrido MI, Lozoff B. Iron deficiency anemia in infancy is associated with altered temporal organization of sleep states in childhood. Pediatr Res. 2007;62:715-719.
11. Morin CM. Insomnia: Psychological Assessment and Management. New York, NY: Guilford Press; 1993:67.
12. Bixler EO, Vgontzas AN, Lin HM, Vela-Bueno A, Kales A. Insomnia in central Pennsylvania. J Psychosom Res. 2002;53:589-592.
13. Jackowska M, Kumari M, Steptoe A. Sleep and biomarkers in the English Longitudinal Study of Ageing: associations with C-reactive protein, fibrinogen, dehydroepiandrosterone sulfate and hemoglobin. Psychoneuroendocrinology. 2013;38:1484-1493.
14. Kim W-H, Kim B-S, Kim S-K, et al. Prevalence of insomnia and associated factors in a community sample of elderly individuals in South Korea. Int Psychogeriatr. 2013;25:1729-1737.
15. National Institute on Aging. About BLSA. Baltimore Longitudinal Study of Aging website. https://www.blsa.nih.gov/about/. Accessed July 14, 2016.
16. Cook JD, Lipschitz DA, Miles LE, Finch CA. Serum ferritin as a measure of iron stores in normal subjects. Am J Clin Nutr. 1974;27:681-687.
17. Gibson RS. Assessment of iron status. In: Gibson RS, ed. Principles of Nutritional Assessment. 2nd ed. Oxford: Oxford University Press; 2005:443-476.
18. WHO. Serum Ferritin Concentrations for the Assessment of Iron Status and Iron Deficiency in Populations. Vitamin and Mineral Nutrition Information System. Geneva, Switzerland: World Health Organization; 2011:1-5.
19. Lennartsson J, Bengtsson C, Hallberg L, Lundgren BK, Tibblin E. Serum iron and transferrin saturation in women with special reference to women with low transferrin saturation. The population study of women in Goteborg 1968-1969. Scand J Haematol. 1979;23:182-196.
20. Gibson RS. Assessment of folate and vitamin B12 status. In: Gibson RS, ed. Principles of Nutritional Assessment. 2nd ed. Oxford: Oxford University Press; 2005:595-640.
21. Fleming DJ, Jacques PF, Tucker KL, et al. Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores. Am J Clin Nutr. 2001;73:638-646.
22. Dallman PR, Siimes MA, Stekel A. Iron deficiency in infancy and childhood. Am J Clin Nutr. 1980;33:86-118.
23. Lynch S. Annex 1: Indicators of the iron status of populations: red blood cell parameters. In: WHO, CDC, eds. Assessing the Iron Status of Populations: Including Literature Reviews: Report of a Joint World Health Organization/Centers for Disease Control and Prevention Technical Consultation on the Assessment of Iron Status at the Population Level. 2nd ed. Geneva, Switzerland: World Health Organization; 2007.
24. Nestel P; International Nutritional Anemia Consultative Group. Adjusting Hemoglobin Values in Program Surveys. Washington, DC: ILSI Human Nutrition Institute; 2002.
25. WHO. Nutritional Anaemias: Report of a WHO Scientific Group. Geneva, Switzerland: World Health Organization; 1968.
26. Levine DW, Lewis MA, Bowen DJ, et al. Reliability and validity of Women's Health Initiative Insomnia Rating Scale. Psychol Assess. 2003;15:137-148.
27. Allen RP, Burchell BJ, MacDonald B, Hening WA, Earley CJ. Validation of the self-completed Cambridge-Hopkins questionnaire (CH-RLSq) for ascertainment of restless legs syndrome (RLS) in a population survey. Sleep Med. 2009;10:1097-1100.
28. Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385-401.
29. Onder G, Penninx BW, Cesari M, et al. Anemia is associated with depression in older adults: results from the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2005;60:1168-1172.
30. StataCorp. Stata Statistical Software: Release 12. 12.1 ed. College Station, TX: StataCorp LP; 2011.
31. Beghe C, Wilson A, Ershler WB. Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature. The American Journal of Medicine. 2004;116(suppl 7A):3S-10S.
32. Thomas KS, Motivala S, Olmstead R, Irwin MR. Sleep depth and fatigue: role of cellular inflammatory activation. Brain Behav Immun. 2011;25:53-58.
33. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.
34. Egerton T, Chastin SF, Stensvold D, Helbostad JL. Fatigue may contribute to reduced physical activity among older people: an observational study. J Gerontol A Biol Sci Med Sci. 2016;71:670-676.
35. King AC, Oman RF, Brassington GS, Bliwise DL, Haskell WL. Moderateintensity exercise and self-rated quality of sleep in older adults. a randomized controlled trial. JAMA. 1997;277:32-37.
36. Zee PC, Attarian H, Videnovic A. Circadian rhythm abnormalities. Continuum. 2013;19:132-147.
37. Gottesman RF, Sojkova J, Beason-Held LL, et al. Patterns of regional cerebral blood flow associated with low hemoglobin in the Baltimore Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci. 2012;67:963-969.
38. Spira AP, Gonzalez CE, Venkatraman VK, et al. Sleep duration and subsequent cortical thinning in cognitively normal older adults. Sleep. 2016;39:1121-1128.
39. Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;104:2263-2268.