Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery

JAMA - Journal of the American Medical Association

Volumn 319, Issue 4, 2018, Pages 365-374

  Friedman, Daniel J ^a,b   Piccini, Jonathan P ^a,b   Wang, Tongrong ^a   Zheng, Jiayin ^a   Malaisrie, S Chris ^c   Holmes, David R ^d   Suri, Rakesh M ^e   Mack, Michael J ^f   Badhwar, Vinay ^g   Jacobs, Jeffrey P ^h   Gaca, Jeffrey G ^a   Chow, Shein Chung ^a   Peterson, Eric D ^a,b   Brennan, J Matthew ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d MAYO CLINIC   (United States)

^e LERNER RESEARCH INSTITUTE   (United States)

^f Baylor University   (United States)

^g WEST VIRGINIA UNIVERSITY   (United States)

^h Hopkins All Children s Heart Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALL CAUSE MORTALITY; AORTIC VALVE REPAIR; ARTICLE; ATRIAL FIBRILLATION; BRAIN HEMORRHAGE; CHA2DS2-VASC SCORE; CLINICAL EFFECTIVENESS; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; FEMALE; HEART SURGERY; HOSPITAL DISCHARGE; HOSPITAL READMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE SURGERY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; THROMBOEMBOLISM; TREATMENT INDICATION; TREATMENT OUTCOME; TREATMENT RESPONSE; AORTIC VALVE; COMPARATIVE STUDY; FOLLOW UP; HEART ATRIUM APPENDAGE; KAPLAN MEIER METHOD; MITRAL VALVE; PROPORTIONAL HAZARDS MODEL; SEPTAL OCCLUDER; STATISTICS AND NUMERICAL DATA; SURGERY;

AGED; AORTIC VALVE; ATRIAL APPENDAGE; ATRIAL FIBRILLATION; CARDIAC SURGICAL PROCEDURES; CORONARY ARTERY BYPASS; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; MITRAL VALVE; PATIENT READMISSION; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; SEPTAL OCCLUDER DEVICE; THROMBOEMBOLISM;

EID: 85041063445     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2017.20125     Document Type: Article

References (27)

1. Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285 (18):2370-2375.
2. Kannel WB, Wolf PA, Benjamin EJ, Levy D. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates. Am J Cardiol. 1998;82(8A):2N-9N.
3. Blackshear JL, Odell JA. Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. Ann Thorac Surg. 1996;61(2):755-759.
4. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007;146(12):857-867.
5. Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014;383(9921):955-962.
6. Hsu JC, Maddox TM, Kennedy KF, et al. Oral anticoagulant therapy prescription in patients with atrial fibrillation across the spectrum of stroke risk: insights from the NCDR PINNACLE Registry. JAMA Cardiol. 2016;1(1):55-62.
7. Holmes DR Jr, Doshi SK, Kar S, et al. Left atrial appendage closure as an alternative to warfarin for stroke prevention in atrial fibrillation: a patient-level meta-analysis. J Am Coll Cardiol. 2015;65(24):2614-2623.
8. Holmes DR, Reddy VY, Turi ZG, et al; PROTECT AF Investigators. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet. 2009;374(9689):534-542.
9. Holmes DR Jr, Kar S, Price MJ, et al. Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J Am Coll Cardiol. 2014;64(1):1-12.
10. Katz ES, Tsiamtsiouris T, Applebaum RM, Schwartzbard A, Tunick PA, Kronzon I. Surgical left atrial appendage ligation is frequently incomplete: a transesophageal echocardiograhic study. J Am Coll Cardiol. 2000;36(2):468-471.
11. January CT, Wann LS, Alpert JS, et al; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014; 64(21):e1-e76.
12. Kirchhof P, Benussi S, Kotecha D, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. 2016;37(38):2893-2962.
13. Jacobs JP, Shahian DM, He X, et al. Penetration, completeness, and representativeness of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. Ann Thorac Surg. 2016;101(1):33-41.
14. Jacobs JP, Edwards FH, Shahian DM, et al. Successful linking of the Society of Thoracic Surgeons adult cardiac surgery database to Centers for Medicare and Medicaid Services Medicare data. Ann Thorac Surg. 2010;90(4):1150-1156.
15. Bennett-Guerrero E, Zhao Y, O’Brien SM, et al. Variation in use of blood transfusion in coronary artery bypass graft surgery. JAMA. 2010;304(14): 1568-1575.
16. Society of Thoracic Surgeons. Adult cardiac surgery data collection. http://www.sts.org/sts-national-database/database-managers/adult -cardiac-surgery-database/data-collection. Accessed February 13, 2017.
17. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D; Modification of Diet in Renal Disease Study Group. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med. 1999; 130(6):461-470.
18. Brennan JM, Edwards FH, Zhao Y, et al; DEcIDE AVR Research Team. Early anticoagulation of bioprosthetic aortic valves in older patients: results from the Society of Thoracic Surgeons Adult Cardiac Surgery National Database. J Am Coll Cardiol. 2012;60(11):971-977.
19. Prasad V, Jena AB. Prespecified falsification end points: can they validate true observational associations? JAMA. 2013;309(3):241-242.
20. Dharmarajan K, Hsieh AF, Lin Z, et al. Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia. JAMA. 2013; 309(4):355-363.
21. Ottenbacher KJ, Karmarkar A, Graham JE, et al. Thirty-day hospital readmission following discharge from postacute rehabilitation in fee-for-service Medicare patients. JAMA. 2014;311(6):604-614.
22. Harder VS, Stuart EA, Anthony JC. Propensity score techniques and the assessment of measured covariate balance to test causal associations in psychological research. Psychol Methods. 2010;15 (3):234-249.
23. Tsai YC, Phan K, Munkholm-Larsen S, Tian DH, La Meir M, Yan TD. Surgical left atrial appendage occlusion during cardiac surgery for patients with atrial fibrillation: a meta-analysis. Eur J Cardiothorac Surg. 2015;47(5):847-854.
24. Zapolanski A, Johnson CK, Dardashti O, et al. Epicardial surgical ligation of the left atrial appendage is safe, reproducible, and effective by transesophageal echocardiographic follow-up. Innovations (Phila). 2013;8(5):371-375.
25. Melduni RM, Schaff HV, Lee HC, et al. Impact of left atrial appendage closure during cardiac surgery on the occurrence of early postoperative atrial fibrillation, stroke, and mortality: a propensity score-matched analysis of 10,633 patients. Circulation. 2017;135(4):366-378.
26. Park-Hansen J. The Left Atrial Appendage Closure by Surgery Study. Presented at: ESC Congress 2017; August 28, 2017; Barcelona, Spain.
27. Whitlock R, Healey J, Vincent J, et al. Rationale and design of the Left Atrial Appendage Occlusion Study (LAAOS) III. Ann Cardiothorac Surg. 2014;3(1): 45-54.