Serum Free Light Chains in CVID—a Marker for Differential Diagnosis

Journal of Clinical Immunology

Volumn 38, Issue 2, 2018, Pages 163-165

  Hanitsch, Leif G ^a   Sotzny, Franziska ^a   Volk, Hans Dieter ^a   Scheibenbogen, Carmen ^a   Wittke, Kirsten ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LAMBDA LIGHT CHAIN; UNCLASSIFIED DRUG; VACCINE; IMMUNOGLOBULIN LIGHT CHAIN;

AUTOIMMUNE DISEASE; AUTOIMMUNE HEMOLYTIC ANEMIA; B LYMPHOCYTE; B LYMPHOCYTE SUBPOPULATION; BRONCHIECTASIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; COMMON VARIABLE IMMUNODEFICIENCY; DIFFERENTIAL DIAGNOSIS; DRUG RESPONSE; ENTEROPATHY; GRANULOMATOSIS; HUMAN; HUMORAL IMMUNE DEFICIENCY; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN DEFICIENCY; IMMUNOPHENOTYPING; LETTER; LYMPHADENOPATHY; MAJOR CLINICAL STUDY; MEMORY CELL; MULTIPLE MYELOMA; PHENOTYPE; PLASMA CELL DYSCRASIA; PNEUMONIA; PREDICTIVE VALUE; PRIORITY JOURNAL; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SPLENOMEGALY; SUBSTITUTION THERAPY; BLOOD;

COMMON VARIABLE IMMUNODEFICIENCY; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; SENSITIVITY AND SPECIFICITY;

EID: 85040696597     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-018-0478-y     Document Type: Letter

References (5)

1. Cunningham-Rundles C. The many faces of common variable immunodeficiency. Hematology Am Soc Hematol Educ Program. 2012;2012:301–5. https://doi.org/10.1182/asheducation-2012.1.301.
2. Compagno N, Cinetto F, Boscaro E, Semenzato G, Agostini C. Serum free light chains in the differential diagnosis and prognosis of primary and secondary hypogammaglobulinemia. J Allergy Clin Immunol. 2015;135(4):1075–7 e6. https://doi.org/10.1016/j.jaci.2014.10.003.
3. Sanchez-Ramon S, Radigan L, Yu JE, Bard S, Cunningham-Rundles C. Memory B cells in common variable immunodeficiency: clinical associations and sex differences. Clin Immunol. 2008;128(3):314–21. https://doi.org/10.1016/j.clim.2008.02.013.
4. Carsetti R, Rosado MM, Donnanno S, Guazzi V, Soresina A, Meini A, et al. The loss of IgM memory B cells correlates with clinical disease in common variable immunodeficiency. J Allergy Clin Immunol. 2005;115(2):412–7. https://doi.org/10.1016/j.jaci.2004.10.048.
5. Schussler E, Beasley MB, Maglione PJ. Lung disease in primary antibody deficiencies. J Allergy Clin Immunol Pract. 2016;4(6):1039–52. https://doi.org/10.1016/j.jaip.2016.08.005.