Effect of combination therapy containing a high-dose carbapenem on mortality in patients with carbapenem-resistant Klebsiella pneumoniae bloodstream infection

International Journal of Antimicrobial Agents

Volumn 51, Issue 2, 2018, Pages 244-248

  Giannella, Maddalena ^a   Trecarichi, Enrico Maria ^b   Giacobbe, Daniele Roberto ^c   De Rosa, Francesco Giuseppe ^d   Bassetti, Matteo ^e   Bartoloni, Alessandro ^f   Bartoletti, Michele ^a   Losito, Angela Raffaella ^b   del Bono, Valerio ^c   Corcione, Silvia ^d   Tedeschi, Sara ^a   Raffaelli, Francesca ^b   Saffioti, Carolina ^c   Spanu, Teresa ^b   Rossolini, Gian Maria ^g   Marchese, Anna ^c   Ambretti, Simone ^a   Cauda, Roberto ^b   Viscoli, Claudio ^c   Lewis, Russell Edward ^a   Viale, Pierluigi ^a   Tumbarello, Mario ^b   more..

^a UNIVERSITY OF BOLOGNA   (Italy)

^b FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

^e S Maria Hospital   (Italy)

^f UNIVERSITY OF FLORENCE   (Italy)

^g CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Bloodstream infection; Carbapenem; Combination therapy; CR KP

Indexed keywords

CARBAPENEM; COLISTIN; MEROPENEM; CARBAPENEM DERIVATIVE; GENTAMICIN; MINOCYCLINE; TIGECYCLINE;

ADULT; AGED; ANTIBIOTIC RESISTANCE; APACHE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; BLOODSTREAM INFECTION; CARBAPENEM-RESISTANT ENTEROBACTERIACEAE; CHARLSON COMORBIDITY INDEX; CHRONIC KIDNEY FAILURE; CLINICAL OUTCOME; COHORT ANALYSIS; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG MEGADOSE; DRUG USE; FEMALE; HOSPITAL ADMISSION; HUMAN; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MULTICENTER STUDY; NONHUMAN; OBSERVATIONAL STUDY; POST HOC ANALYSIS; PRIORITY JOURNAL; SEPTIC SHOCK; SURGICAL WARD; TEACHING HOSPITAL; ANALOGS AND DERIVATIVES; BACTEREMIA; CLASSIFICATION; CLINICAL TRIAL; COMBINATION DRUG THERAPY; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; MICROBIOLOGY; MIDDLE AGED; PHYSIOLOGY; PROPENSITY SCORE; TERTIARY CARE CENTER; TREATMENT OUTCOME;

AGED; BACTEREMIA; CARBAPENEM-RESISTANT ENTEROBACTERIACEAE; CARBAPENEMS; COLISTIN; DRUG RESISTANCE, BACTERIAL; DRUG THERAPY, COMBINATION; FEMALE; GENTAMICINS; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; MINOCYCLINE; PROPENSITY SCORE; TERTIARY CARE CENTERS; TREATMENT OUTCOME;

EID: 85040603189     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2017.08.019     Document Type: Article

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