cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels

Circulation

Volumn 136, Issue 24, 2017, Pages 2337-2355

  Frankenreiter, Sandra ^a   Bednarczyk, Piotr ^a   Kniess, Angelina ^a   Bork, Nadja I ^a   Straubinger, Julia ^a   Koprowski, Piotr ^a   Wrzosek, Antoni ^a   Mohr, Eva ^a   Logan, Angela ^a   Murphy, Michael P ^a   Gawaz, Meinrad ^a   Krieg, Thomas ^a   Szewczyk, Adam ^a   Nikolaev, Viacheslav O ^a   Ruth, Peter ^a   Lukowski, Robert ^a  

^a Department of Medicine   (Germany)

Author keywords

cyclic guanosine 3',5' monophosphate; ischemic postconditioning; ischemic preconditioning; mitochondria; myocardial infarction; nitric oxide sensitive guanylyl cyclase; voltage and Ca2+ activated potassium channel BK

Indexed keywords

BENZOIC ACID DERIVATIVE; CARDIOTONIC AGENT; CINACIGUAT; CYCLIC AMP DEPENDENT PROTEIN KINASE 1; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NITRIC OXIDE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIOCIGUAT;

129 MOUSE; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; DISEASE MODEL; GENETICS; HEART INFARCTION; HUMAN; ISCHEMIC PRECONDITIONING; KNOCKOUT MOUSE; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REPERFUSION INJURY;

ANIMALS; BENZOATES; CARDIOTONIC AGENTS; CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE I; DISEASE MODELS, ANIMAL; HUMANS; ISCHEMIC PRECONDITIONING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; NITRIC OXIDE; PYRAZOLES; PYRIMIDINES; REPERFUSION INJURY;

EID: 85039043126     PISSN: None     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.117.028723     Document Type: Article

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