Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

The Lancet

Volumn 391, Issue 10123, 2018, Pages 850-859

  Bath, Philip M ^a,b   Woodhouse, Lisa J ^a   Appleton, Jason P ^a,b   Beridze, Maia ^c   Christensen, Hanne ^d   Dineen, Robert A ^a   Duley, Lelia ^a   England, Timothy J ^a   Flaherty, Katie ^a   Havard, Diane ^a   Heptinstall, Stan ^a   James, Marilyn ^a   Krishnan, Kailash ^a,b   Markus, Hugh S ^e   Montgomery, Alan A ^a   Pocock, Stuart J ^f   Randall, Marc ^g   Ranta, Annemarei ^h   Robinson, Thompson G ⁱ   Scutt, Polly ^a   Venables, Graham S ^j   Sprigg, Nikola ^a,b   Christensen, L M ^k   Bentsen, L ^k   Krarup Hansen, C ^k   Thomsen, T T ^k   Kruuse, C ^k   Jensen, H H ^k   Hansen, S S ^k   Petrovic, V ^k   Beridze, N ^k   Kakabadze, N ^k   Kherkheulidze, T ^k   Kakabadze, D ^k   Toidze, I ^k   Lobjanidze, N ^k   Akiashvili, N ^k   Tevdoradze, A ^k   Khizanishvili, N ^k   Tsanava, T ^k   Taylor, R ^k   Iniesta, I ^k   Kok, J ^k   Duignan, J ^k   Funnell, M ^k   Cariga, P ^k   Rodriguez, M ^k   Watson, I J ^k   Tennant, S ^k   Macleod, M ^k   Furnace, J ^k   Gow, H ^k   Irvine, J ^k   Joyson, A ^k   Nelson, S ^k   Taylor, V ^k   Smith, M ^k   Bellfield, R ^k   Hairsine, B ^k   Davies, R ^k   Dodd, A ^k   Corrigan, J ^k   Doherty, M ^k   Ahmed, A ^k   Denniss, C ^k   Johnson Holland, S ^k   Kay, K A ^k   Palau, R Icart ^k   Auld, G ^k   Daboo, P ^k   Erande, R ^k   Grimwood, G ^k   Hove, D ^k   Howaniec, L ^k   Redjep, O ^k   Rangasamay, R ^k   Butt, G ^k   Sandler, D ^k   Reddan, J ^k   Stafford, S ^k   McIlmoyle, J ^k   Maguire, S ^k   Murphy, P ^k   Chambers, J ^k   Guthrie, L ^k   Osborn, M ^k   Steele, A ^k   Burn, M ^k   Benford, A ^k   Misra, A ^k   Hilton, D ^k   O'Brien, E ^k   Amis, E ^k   Finlay, S ^k   Mitchell, J ^k   Geraghty, O ^k   Harvey, K ^k   Hazel, B ^k   Mashate, S ^k   Wilding, P ^k   Sajid, M ^k   Ball, M ^k   Gascoyne, R ^k   Sivakumar, R ^k   Wright, A ^k   Chatterjee, K ^k   Booth, S ^k   Eccleson, H ^k   Kelly, C ^k   Leason, S ^k   Perkins, C ^k   Bruce, D ^k   Brown, E ^k   Clayton, S ^k   Garside, M ^k   Rogers, G ^k   Lawrence, E ^k   Mahmood, S ^k   Watchurst, C ^k   Chadha, D ^k   Glover, L ^k   Holford, L ^k   Smith, K ^k   Walstow, D ^k   Williams, R ^k   O'Shea, L ^k   Goodsell, J ^k   Athulathmudali, C ^k   Barbon, E ^k   Namushi, R ^k   Jacob, P ^k   Johnson, L ^k   Morse, D ^k   McGhee, C ^k   Speirs, O ^k   Atkinson, S ^k   Peacocke, A ^k   Langhorne, P ^k   Graham, R ^k   Wright, F ^k   McAlpine, C ^k   Ravindrane, A ^k   Bajoriene, M ^k   Matter, L ^k   Windebank, S ^k   Giallombardo, E ^k   Dellafera, D ^k   Eglinton, C ^k   Wilson, J ^k   Broughton, D ^k   Chapman, K ^k   Dixon, L ^k   Zaidi, M ^k   Ayes, K ^k   Kessell, J ^k   Manawadu, D ^k   Adegbaju, O ^k   Aeron Thomas, J ^k   Anderson, K ^k   Brigden, A ^k   Cattermole, E ^k   Good, J ^k   Hassan, S ^k   Khoromana, E ^k   Lee Carbon, L ^k   Marks, K ^k   Mckenzie, E ^k   Sikondari, N ^k   Cooper, M ^k   Whysall, K ^k   Wynter, I ^k   Bamford, J ^k   Hassan, A ^k   Wanklyn, P ^k   Kambafwile, M ^k   Makawa, L ^k   Waugh, D ^k   Veraque, E ^k   Soliman, M G G ^k   Arif, S ^k   Brown, R ^k   Butler, S ^k   Hewitt, C ^k   Hindle, J ^k   Pusalkar, A ^k   Beadle, H ^k   Chan, K ^k   Siddiqui, M ^k   Dangri, P ^k   Buddha, S ^k   Asokanathan, A ^k   Mistri, A ^k   Eveson, D ^k   Musarrat, K ^k   Manning, L ^k   Anand, S ^k   Christian, P ^k   Khan, S ^k   Patel, C ^k   Sein, M ^k   Banns, J ^k   Gibson, E ^k   Gordon, T ^k   Gruenbeck, Y ^k   Wong, S ^k   Datta, P ^k   Bateman, G ^k   Jackson, L ^k   Needle, A ^k   Duodu, Y ^k   Oliver, R ^k   Padilla Harris, C ^k   Barber, M ^k   Esson, D ^k   Brodie, F ^k   McInnes, C ^k   Fotherby, K ^k   Butler, D ^k   Morgan, D ^k   Preece, K ^k   Willberry, A ^k   Dent, M ^k   Hammonds, F ^k   Hunt, J ^k   Vernon, C ^k   O'Kane, D ^k   Faola, F ^k   Lai, P ^k   O'Callaghan, J ^k   Smith, C ^k   Price, C ^k   Lakey, R ^k   Riddell, V ^k   Smith, A ^k   Storey, G ^k   Munshi, S ^k   Buck, A ^k   Clarke, J ^k   Gilzeane, N ^k   Godfrey, M ^k   Keshvara, R ^k   Richardson, C ^k   Roffe, J ^k   Ryan, L ^k   Shelton, F ^k   Sunman, W ^k   Tittle, A ^k   Tomlinson, J ^k   Whittamore, K ^k   Wilkes, G ^k   Owusu Agyei, P ^k   Temple, N ^k   Mangion, D ^k   Hardwick, A ^k   Netherton, K ^k   Nor, A Mohd ^k   Hyams, B ^k   Norman, S ^k   Persad, N ^k   Ragab, S ^k   Dickson, C ^k   Dube, J ^k   Jinks, E ^k   Knops, K ^k   Wadams, B ^k   Ali, K ^k   Gaylard, J ^k   Spurling, G ^k   Sztriha, L ^k   Ajao, T ^k   Alao, M ^k   Chan, F K ^k   Webster, P ^k   Howard, P ^k   Dobson, T J ^k   Hyatt, L ^k   Sims, D ^k   Cunningham, J ^k   Esisi, B ^k   Cassidy, T ^k   Bokhari, M ^k   McClelland, B ^k   Mokoena, B ^k   Gunathilagan, G ^k   Jones, S ^k   Reader, M ^k   Thomas, G ^k   Tilby, S ^k   Findlay, P ^k   Barrett, F ^k   Leslie, F ^k   Ross, S ^k   Shread, I ^k   Okwera, J ^k   Howe, J ^k   Harrington, F ^k   Courtauld, G ^k   Schofield, C ^k   Donnelly, R ^k   Maddula, M ^k   Scott, J ^k   Beavan, J ^k   Muhidden, K ^k   Memon, I ^k   Clarke, M ^k   Hedstrom, A ^k   Mills, L ^k   Hemsley, A ^k   Bowring, A ^k   Boxall, L ^k   Kingwell, H ^k   Keenan, S ^k   Roughan, C ^k   Manoj, A ^k   Cox, P ^k   Fletcher, G ^k   Lopez, P ^k   Emsley, H ^k   Gregary, B ^k   McLoughlin, A ^k   Raj, S ^k   Roffe, C ^k   Abano, N ^k   Barry, A ^k   Butler, A ^k   Carpio, R ^k   Castro, K ^k   Finney, K ^k   Gomm, S ^k   Hiden, J ^k   Grocott, J ^k   Lyjko, S ^k   Maguire, H ^k   Remegoso, A ^k   Sanyal, R ^k   Stevens, S ^k   Natarajan, I ^k   Chembala, J ^k   Muddegowda, G ^k   Warusevitane, A ^k   Blight, A ^k   Balazikova, O ^k   Lawlor, C ^k   Shaw, L ^k   Button, D ^k   Howcroft, D ^k   Lucas, S ^k   Madigan, B ^k   McCann, S ^k   Dixit, A ^k   Barkat, A ^k   Davis, J ^k   Fawcett, M ^k   Finlay, L ^k   Guy, H ^k   Hays, C ^k   Hogg, V ^k   Horsley, E ^k   Hubbuck, C ^k   Pringle, C ^k   Stevenson, C ^k   Storey, K ^k   Thompson, T ^k   Woodward, S ^k   Banerjee, A ^k   Allcock, C ^k   Merotra, S ^k   Douglass, C ^k   Campbell, E ^k   Jarapa, R ^k   Johnes, M ^k   Keaveney, C ^k   Marsden, T ^k   Naing, Z ^k   Perez, J ^k   Shaw, K ^k   Black, T ^k   Anthony, A ^k   Clarke, C ^k   Paterson, J ^k   Deighton, K ^k   Temlett, E ^k   Blank, C ^k   Doyle, C ^k   Duty, S ^k   Gill, K ^k   Harkness, K ^k   Kamara, C ^k   Richards, E ^k   Elfandi, K ^k   Guyler, P ^k   Harman, P ^k   Khuoge, C ^k   Kunhunny, S ^k   Tysoe, S ^k   Moynihan, B ^k   Adedoyin, T ^k   Chopra, N ^k   Dayal, N ^k   Ghatala, R ^k   Jeyaraj, N ^k   Jones, I ^k   Kennedy, F ^k   Kerin, L ^k   Khanom, N ^k   Lewis, S ^k   Maheswaran, S ^k   Montague, L ^k   Niemierko, M ^k   O'Reilly, J ^k   Trippier, S ^k   Watson, F ^k   Wilkinson, P ^k   Young, E ^k   Dizayee, K ^k   Cochrane, H ^k   O'Connell, J ^k   Mokoena, L ^k   Osborne, E ^k   Nair, A ^k   Greig, J ^k   Jenkins, C ^k   Powell, J ^k   Price, F ^k   Chowdhury, M ^k   Brixey, S ^k   Hunt, L ^k   Rands, N ^k   Rose, G ^k   Stoddart, S ^k   Srinivasan, M ^k   Motherwell, N ^k   Shekhar, R ^k   Fuller, T ^k   Lankester, A ^k   Lingwood, P ^k   Rankin, C ^k   Webb, H ^k   Jupp, B ^k   Bell, J ^k   Hann, G ^k   Longland, B ^k   Ovington, C ^k   Bhaskaran, B ^k   Ayres, G ^k   Bailey, C ^k   Bearne, H ^k   Buxton, J ^k   Fitzell, P ^k   Hilaire, C ^k   Kelly, D ^k   Szabo, S ^k   Tomlin, D ^k   Gamble, E ^k   Charles, B ^k   Kumar, R ^k   Fluskey, T ^k   Mellor, Z ^k   Peters, J ^k   Sutton, V ^k   Kenton, A ^k   Martin, I ^k   Nyabadza, S ^k   Ghosh, S ^k   Henry, M ^k   Kumar, B ^k   Ambulo, C ^k   Crawford, S ^k   Nozedar, T ^k   Platton, M ^k   Cvoro, V ^k   Couser, M ^k   McCormick, K ^k   Wilkinson, D ^k   Javaid, K ^k   Hurdowar, S ^k   Attygalle, T ^k   Sundayi, S ^k   Orugun, O ^k   Crowther, H ^k   Jolly, R ^k   Poultney, U ^k   Azim, A ^k   Krasinska Chavez, M ^k   White, J ^k   Sengupta, N ^k   Margalef, J ^k   Metiu, M G ^k   Meenakshisundaram, S ^k   Dealing, S ^k   Hargroves, D ^k   Beranova, E ^k   Cowie, L ^k   Rudenko, H ^k   Thomson, A ^k   Verrion, A ^k   Rashed, K ^k   Board, S ^k   Buckley, C ^k   Hayward, D ^k   Jenkins, K ^k   Keeling, E ^k   Rowland Axe, R ^k   Vickers, C ^k   Wood, D ^k   Lehman, A ^k   Patel, M ^k   Russell, H ^k   Rehman, H ^k   Forrest, D ^k   Farren, P ^k   more..

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^c Hospital of War Veterans   (Georgia)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^g LEEDS GENERAL INFIRMARY   (United Kingdom)

^h UNIVERSITY OF OTAGO   (New Zealand)

ⁱ UNIVERSITY OF LEICESTER   (United Kingdom)

^j ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^k NONE

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; DIPYRIDAMOLE; ANTITHROMBOCYTIC AGENT; TICLOPIDINE;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; COMBINATION DRUG THERAPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG FATALITY; DRUG SAFETY; DRUG USE; EPIDURAL HEMATOMA; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MULTICENTER STUDY; NASOGASTRIC DRUG ADMINISTRATION; OPEN STUDY; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SUBDURAL HEMATOMA; SUPERIORITY TRIAL; TRANSIENT ISCHEMIC ATTACK; ACUTE DISEASE; ANALOGS AND DERIVATIVES; CEREBROVASCULAR ACCIDENT; CHEMICALLY INDUCED; CLINICAL TRIAL; COMPARATIVE STUDY; DENMARK; FIBRINOLYTIC THERAPY; ISCHEMIA; METHODOLOGY; MIDDLE AGED; NEW ZEALAND; PATHOLOGY; PROCEDURES; RECURRENT DISEASE; RISK ASSESSMENT; STANDARDS; TREATMENT OUTCOME; UNITED KINGDOM;

ACUTE DISEASE; AGED; ASPIRIN; BRAIN ISCHEMIA; DENMARK; DIPYRIDAMOLE; DRUG THERAPY, COMBINATION; FEMALE; GEORGIA; HEMORRHAGE; HUMANS; ISCHEMIA; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; NEW ZEALAND; PLATELET AGGREGATION INHIBITORS; PROSPECTIVE STUDIES; RECURRENCE; RESEARCH DESIGN; RISK ASSESSMENT; STROKE; THROMBOLYTIC THERAPY; TICLOPIDINE; TREATMENT OUTCOME; UNITED KINGDOM;

EID: 85038846371     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(17)32849-0     Document Type: Article

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